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Drug Metabolism and Disposition Fast Forward
First published on March 5, 2008; DOI: 10.1124/dmd.108.021113

0090-9556/08/3606-981-985$20.00
DMD 36:981-985, 2008

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The Development of Drug Metabolism Research as Expressed in the Publications of ASPET: Part 2, 1959–1983

Patrick J. Murphy

College of Pharmacy and Health Sciences, Butler University, Indianapolis, Indiana

In 25 years, drug metabolism research went from using subcellular particles of undefined content to an understanding of metabolism at the molecular level. The discoveries of cytochrome P450, enzyme induction, reactive intermediates, and genetic polymorphisms were milestones in the field. New publications from the American Society for Pharmacology and Experimental Therapeutics chronicled the discoveries and provided communications to advance the science of drug metabolism.

Address correspondence to: Dr. Patrick J. Murphy, 3589 Brumley Mews, Carmel, IN 46033. E-mail: pjmurphy12{at}aol.com






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