DMD Noab BioDiscoveries - Shaping Drug Discovery

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July 1986; 14 (4)   [Index by Author]       Other Issues:  
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To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Articles:

WW Weber
The molecular basis of hereditary acetylation polymorphisms
Drug Metab Dispos 1986 14: 377-381. [PDF]  

HH Andres and WW Weber
N-acetylation pharmacogenetics. Michaelis-Menten constants for arylamine drugs as predictors of their N-acetylation rates in vivo
Drug Metab Dispos 1986 14: 382-385. [Abstract] [PDF]  

A Pathiratne, RL Puyear, and JD Brammer
Activation of 14C-toluene to covalently binding metabolites by rat liver microsomes
Drug Metab Dispos 1986 14: 386-391. [Abstract] [PDF]  

SL Wang, SA Rice, MT Serra, and B Gross
Purification and identification of rat hepatic cytosolic enzymes responsible for defluorination of methoxyflurane and fluoroacetate
Drug Metab Dispos 1986 14: 392-398. [Abstract] [PDF]  

KB Wallace
Aglycosylation and disposition of doxorubicin in isolated rat liver nuclei and microsomes
Drug Metab Dispos 1986 14: 399-404. [Abstract] [PDF]  

RT Schillings and SF Sisenwine
Disposition of (5H-dibenzo [a,d]cyclohepten-5-ylidene)acetic acid in laboratory animals
Drug Metab Dispos 1986 14: 405-412. [Abstract] [PDF]  

CE Modly, M Das, PS Don, CL Marcelo, H Mukhtar, and DR Bickers
Capsaicin as an in vitro inhibitor of benzo(a)pyrene metabolism and its DNA binding in human and murine keratinocytes
Drug Metab Dispos 1986 14: 413-416. [Abstract] [PDF]  

SJ Borghoff and LS Birnbaum
Age-related changes in the metabolism and excretion of allyl isothiocyanate. A model compound for glutathione conjugation
Drug Metab Dispos 1986 14: 417-422. [Abstract] [PDF]  

RA Young and HM Mehendale
In vitro metabolism of amiodarone by rabbit and rat liver and small intestine
Drug Metab Dispos 1986 14: 423-429. [Abstract] [PDF]  

RH Jr Meacham, SF Sisenwine, AL Liu, CJ Kick, I Barinov, and HW Ruelius
Inhibition of ciramadol glucuronidation by benzodiazepines
Drug Metab Dispos 1986 14: 430-436. [Abstract] [PDF]  

PH Beaune, PG Kremers, LS Kaminsky, J De Graeve, A Albert, and FP Guengerich
Comparison of monooxygenase activities and cytochrome P-450 isozyme concentrations in human liver microsomes
Drug Metab Dispos 1986 14: 437-442. [Abstract] [PDF]  

AW Rettenmeier, WP Gordon, KS Prickett, RH Levy, JS Lockard, KE Thummel, and TA Baillie
Metabolic fate of valproic acid in the rhesus monkey. Formation of a toxic metabolite, 2-n-propyl-4-pentenoic acid
Drug Metab Dispos 1986 14: 443-453. [Abstract] [PDF]  

AW Rettenmeier, WP Gordon, KS Prickett, RH Levy, and TA Baillie
Biotransformation and pharmacokinetics in the rhesus monkey of 2-n- propyl-4-pentenoic acid, a toxic metabolite of valproic acid
Drug Metab Dispos 1986 14: 454-464. [Abstract] [PDF]  

SJ Kolis, EJ Postma, TH Williams, and GJ Sasso
Identification of trimoprostil metabolites excreted in rat bile formed by oxidation and taurine conjugation
Drug Metab Dispos 1986 14: 465-470. [Abstract] [PDF]  

AS Salhab, MO James, SL Wang, and KT Shiverick
Positional metabolism of benzo(a)pyrene in rat placenta and maternal liver. Comparison of induction effects
Drug Metab Dispos 1986 14: 471-476. [Abstract] [PDF]  

BM Gerardy, D Kapusta, P Dumont, and JH Poupaert
Synthesis, characterization, and quantitation of para-hydroxymethadone, a metabolite of methadone in the rat
Drug Metab Dispos 1986 14: 477-481. [Abstract] [PDF]  

KA Walker, HE Barber, and GM Hawksworth
Mechanism responsible for altered propranolol disposition in adjuvant- induced arthritis in the rat
Drug Metab Dispos 1986 14: 482-486. [Abstract] [PDF]  

T Kumano, T Yoshioka, and T Uematsu
Comparative effect of chemical structure of chlorinated N-hydroxy-N- acyl-aminobiphenyl ethers and their related compounds on rat liver cytosol-catalyzed transacylation
Drug Metab Dispos 1986 14: 487-493. [Abstract] [PDF]  

V Dimov, K Green, M Bygdeman, and NJ Christensen
Metabolism of 16, 16-dimethyl-trans-delta 2-prostaglandin E1 methyl ester (ONO-802) following intravenous and vaginal administration to pregnant women
Drug Metab Dispos 1986 14: 494-502. [Abstract] [PDF]  

PC Smith and LZ Benet
Characterization of the isomeric esters of zomepirac glucuronide by proton NMR
Drug Metab Dispos 1986 14: 503-505. [PDF]  

WL Nelson and HU Shetty
Stereoselective oxidative metabolism of propranolol in the microsomal fraction from rat and human liver. Use of deuterium labeling and pseudoracemic mixtures
Drug Metab Dispos 1986 14: 506-508. [PDF]  

K Mamada, Y Kasuya, and S Baba
Pharmacokinetic equivalence of deuterium-labeled and unlabeled phenytoin
Drug Metab Dispos 1986 14: 509-511. [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


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