DMD Noab BioDiscoveries - Shaping Drug Discovery

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September 1986; 14 (5)   [Index by Author]       Other Issues:  
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To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Articles:

IA de Lannoy and KS Pang
Presence of a diffusional barrier on metabolite kinetics: enalaprilat as a generated versus preformed metabolite
Drug Metab Dispos 1986 14: 513-520. [Abstract]  

GB Quistad, LE Staiger, and DA Schooley
The role of carnitine in the conjugation of acidic xenobiotics
Drug Metab Dispos 1986 14: 521-525. [Abstract] [PDF]  

LA Shipley, PI Eacho, DJ Sweeny, and M Weiner
Inhibition of glucuronidation and sulfation by dibutyryl cyclic AMP in isolated rat hepatocytes
Drug Metab Dispos 1986 14: 526-531. [Abstract] [PDF]  

WG Taylor
Metabolism of N,N-diethyl-meta-toluamide by rat liver microsomes
Drug Metab Dispos 1986 14: 532-539. [Abstract] [PDF]  

CT Gombar, K Straub, P Levandoski, L Gutzait, J Swagzdis, C Garvie, G Joseph, BD Potts, and BA Mico
Pharmacokinetics, metabolism, and disposition of 6-chloro-2,3,4,5- tetrahydro-3-methyl-1H-3-benzazepine (SK&F 86466) in rats and dogs
Drug Metab Dispos 1986 14: 540-548. [Abstract] [PDF]  

LB LaCagnin, HD Colby, and JP O'Donnell
The oxidative metabolism of hydralazine by rat liver microsomes
Drug Metab Dispos 1986 14: 549-554. [Abstract] [PDF]  

LI Harrison, D Schuppan, SR Rohlfing, AR Hansen, JF Gerster, CS Hansen, ML Funk, and RE Ober
Disposition of radiolabeled flumequine in rat and dog
Drug Metab Dispos 1986 14: 555-558. [Abstract] [PDF]  

K Nagata, DJ Liberato, JR Gillette, and HA Sasame
An unusual metabolite of testosterone. 17 beta-Hydroxy-4,6- androstadiene-3-one
Drug Metab Dispos 1986 14: 559-565. [Abstract] [PDF]  

DW Hein, WG Kirlin, F Ogolla, A Trinidad, LK Thompson, and RJ Ferguson
The role of acetylator genotype on hepatic and extrahepatic acetylation, deacetylation, and sulfation of 2-aminofluorene, 2- acetylaminofluorene, and N-hydroxy-2-acetylaminofluorene in the inbred hamster
Drug Metab Dispos 1986 14: 566-573. [Abstract] [PDF]  

WF Pool, AA Houdi, LA Damani, WJ Layton, and PA Crooks
Isolation and characterization of N-methyl-N'-oxonicotinium ion, a new urinary metabolite of R-(+)-nicotine in the guinea pig
Drug Metab Dispos 1986 14: 574-579. [Abstract] [PDF]  

NS Yee and L Shargel
Effect of cimetidine or ranitidine pretreatment on hepatic mixed function oxidase activity in the rat
Drug Metab Dispos 1986 14: 580-584. [Abstract] [PDF]  

BH Shapiro, RC Albucher, JN MacLeod, and MS Bitar
Normal levels of hepatic drug-metabolizing enzymes in neonatally induced, growth hormone-deficient adult male and female rats
Drug Metab Dispos 1986 14: 585-589. [Abstract] [PDF]  

SH Chiu, E Sestokas, R Taub, RP Buhs, M Green, R Sestokas, WJ Vandenheuvel, BH Arison, and TA Jacob
Metabolic disposition of ivermectin in tissues of cattle, sheep, and rats
Drug Metab Dispos 1986 14: 590-600. [Abstract] [PDF]  

CE Zoetemelk, IH Oei, B van Meeteren-Walchli, W Onkenhout, A van der Gen, and DD Breimer
Biotransformation of 1,2-dibromopropane in rats into four mercapturic acid derivatives
Drug Metab Dispos 1986 14: 601-607. [Abstract] [PDF]  

W Onkenhout, WM van Loon, W Buijs, A van der Gen, and NP Vermeulen
Biotransformation and quantitative determination of sulfur-containing metabolites of 1,4-dibromobutane in the rat
Drug Metab Dispos 1986 14: 608-612. [Abstract] [PDF]  

C Baarnhielm, A Backman, KJ Hoffmann, and L Weidolf
Biotransformation of felodipine in liver microsomes from rat, dog, and man
Drug Metab Dispos 1986 14: 613-618. [Abstract] [PDF]  

WH Soine, PJ Soine, BW Overton, and LK Garrettson
Product enantioselectivity in the N-glucosylation of amobarbital
Drug Metab Dispos 1986 14: 619-621. [PDF]  

FA Redegeld and J Noordhoek
Active tubular secretion of 1-naphthyl-beta-D-glucuronide in the isolated perfused rat kidney
Drug Metab Dispos 1986 14: 622-624. [PDF]  

T Zysset and C Tlach
Aminopyrine pharmacokinetics in the rat may depend on hepatic blood flow
Drug Metab Dispos 1986 14: 625-626. [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


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