DMD Noab BioDiscoveries - Shaping Drug Discovery

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March 1987; 15 (2)   [Index by Author]       Other Issues:  
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To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Articles:

MG Miller and DJ Jollow
Relationship between sulfotransferase activity and susceptibility to acetaminophen-induced liver necrosis in the hamster
Drug Metab Dispos 1987 15: 143-150. [Abstract] [PDF]  

A Shah and D Jung
Dose-dependent pharmacokinetics of ibuprofen in the rat
Drug Metab Dispos 1987 15: 151-154. [Abstract] [PDF]  

UG Eriksson, RC Brasch, and TN Tozer
Nonenzymatic bioreduction in rat liver and kidney of nitroxyl spin labels, potential contrast agents in magnetic resonance imaging
Drug Metab Dispos 1987 15: 155-160. [Abstract] [PDF]  

JF Newton, KM Straub, RH Dewey, CD Perchonock, TB Leonard, ME McCarthy, JG Gleason, and RD Eckardt
In vitro microsomal metabolism of the leukotriene receptor antagonist, 5-(2-dodecylphenyl)-4,6-dithianonanedioic acid (SK&F 102,081)
Drug Metab Dispos 1987 15: 161-167. [Abstract] [PDF]  

JF Newton, KM Straub, GY Kuo, CD Perchonock, ME McCarthy, JG Gleason, and RK Lynn
In vivo metabolism of the leukotriene receptor antagonist, 5-(2- dodecylphenyl)-4,6-dithianonanedioic acid (SK&F 102,081) in the guinea pig
Drug Metab Dispos 1987 15: 168-176. [Abstract] [PDF]  

JB 3d Watkins and TP Dykstra
Alterations in biliary excretory function by streptozotocin-induced diabetes
Drug Metab Dispos 1987 15: 177-183. [Abstract] [PDF]  

AR Samuels, L Theilmann, YR Stollman, AW Wolkoff, and MM Bhargava
Uptake, metabolism, and secretion of 3'-methyl-N,N-dimethyl-4- aminoazobenzene by isolated perfused rat liver
Drug Metab Dispos 1987 15: 184-188. [Abstract] [PDF]  

SB Rao and HM Mehendale
Uptake and disposition of putrescine, spermidine, and spermine by rabbit lungs
Drug Metab Dispos 1987 15: 189-194. [Abstract] [PDF]  

DM Dulik and C Fenselau
Conversion of melphalan to 4-(glutathionyl)phenylalanine. A novel mechanism for conjugation by glutathione-S-transferases
Drug Metab Dispos 1987 15: 195-199. [Abstract] [PDF]  

M Agosin and GT Ankley
Conversion of N,N-dimethylaniline to N,N-dimethylaniline-N-oxide by a cytosolic flavin-containing enzyme from Trypanosoma cruzi
Drug Metab Dispos 1987 15: 200-203. [Abstract] [PDF]  

M Busby and LJ Lesko
Pharmacokinetic interaction between theophylline and chloramphenicol in rats
Drug Metab Dispos 1987 15: 204-206. [Abstract] [PDF]  

DM McPhillips, JR Kalin, and DL Hill
The pharmacokinetics of all-trans-retinoic acid and N-(2- hydroxyethyl)retinamide in mice as determined with a sensitive and convenient procedure. Solid-phase extraction and reverse-phase high performance liquid chromatography
Drug Metab Dispos 1987 15: 207-211. [Abstract] [PDF]  

JH Lin, LE Los, EH Ulm, and DE Duggan
Urinary excretion kinetics of famotidine in rats
Drug Metab Dispos 1987 15: 212-216. [Abstract] [PDF]  

CA Shively and ES Vesell
In vivo and in vitro biotransformation of theobromine by phenobarbital- and 3-methylcholanthrene-inducible cytochrome P-450 monooxygenases in rat liver. Role of thiol compounds
Drug Metab Dispos 1987 15: 217-224. [Abstract] [PDF]  

DL Schmucker and RK Wang
Effects of aging on the properties of rhesus monkey liver microsomal NADPH-cytochrome c (P-450) reductase
Drug Metab Dispos 1987 15: 225-232. [Abstract] [PDF]  

AS Salhab, J Applewhite, MW Couch, RT Okita, and KT Shiverick
Extraction of omega- and omega-1-hydroxylauric acids with ethyl acetate results in formation of acetoxy products
Drug Metab Dispos 1987 15: 233-236. [Abstract] [PDF]  

ME Campbell, DM Grant, T Inaba, and W Kalow
Biotransformation of caffeine, paraxanthine, theophylline, and theobromine by polycyclic aromatic hydrocarbon-inducible cytochrome(s) P-450 in human liver microsomes
Drug Metab Dispos 1987 15: 237-249. [Abstract] [PDF]  

R Mehvar, F Jamali, MW Watson, and D Skelton
Pharmacokinetics of tetrabenazine and its major metabolite in man and rat. Bioavailability and dose dependency studies
Drug Metab Dispos 1987 15: 250-255. [Abstract] [PDF]  

ME McManus, I Stupans, W Burgess, JA Koenig, PM Hall, and DJ Birkett
Flavin-containing monooxygenase activity in human liver microsomes
Drug Metab Dispos 1987 15: 256-261. [Abstract] [PDF]  

T Kobayashi, H Ando, J Sugihara, and S Harigaya
Metabolism of ethyl 2-(4-chlorophenyl)-5-(2-furyl)-oxazole-4-acetate, a new hypolipidemic agent, in the rat, rabbit, and dog. Glucuronidation of carboxyl group and cleavage of furan ring
Drug Metab Dispos 1987 15: 262-266. [Abstract] [PDF]  

JE Sinsheimer and CJ Freeman
Mitotane (1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane) metabolism in perfusion studies with dog adrenal glands
Drug Metab Dispos 1987 15: 267-269. [PDF]  

JO Peggins, TF McMahon, WP Beierschmitt, and M Weiner
Comparison of hepatic and renal metabolism of acetaminophen in male and female miniature swine
Drug Metab Dispos 1987 15: 270-273. [PDF]  

BA Mico, DA Federowicz, E Burak, and JE Swagzdis
In vivo inhibition of phenacetin oxidation by suicide substrate 1- aminobenzotriazole
Drug Metab Dispos 1987 15: 274-276. [PDF]  

PJ Wedlund, BJ Sweetman, GR Wilkinson, and RA Branch
Pharmacogenetic association between the formation of 4- hydroxymephenytoin and a new metabolite of S-mephenytoin in man
Drug Metab Dispos 1987 15: 277-279. [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


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