DMD Noab BioDiscoveries - Shaping Drug Discovery

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May 1987; 15 (3)   [Index by Author]       Other Issues:  
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To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Articles:

RL Dills, SR Howell, and CD Klaassen
Hepatic UDP-glucose and UDP-glucuronic acid synthesis rates in rats during a reduced energy state
Drug Metab Dispos 1987 15: 281-288. [Abstract] [PDF]  

EG Snyderwine and A Hunter
Metabolism and distribution of 14C- and 35S-labeled carbon disulfide in immature rats of different ages
Drug Metab Dispos 1987 15: 289-294. [Abstract] [PDF]  

LA Reinke, M Nakamura, L Logan, HD Christensen, and JM Carney
In vivo and in vitro 1-methylxanthine metabolism in the rat. Evidence that the dehydrogenase form of xanthine oxidase predominates in intact perfused liver
Drug Metab Dispos 1987 15: 295-299. [Abstract] [PDF]  

LK Keefer, AJ Streeter, LY Leung, WC Perry, HS Hu, and TA Baillie
Pharmacokinetic and deuterium isotope effect studies on the metabolism of formaldehyde and formate to carbon dioxide in rats in vivo
Drug Metab Dispos 1987 15: 300-304. [Abstract] [PDF]  

RC Peffer, DJ Abraham, MA Zemaitis, LK Wong, and JD Alvin
3,4-Dichlorobenzyloxyacetic acid is extensively metabolized to a taurine conjugate in rats
Drug Metab Dispos 1987 15: 305-311. [Abstract] [PDF]  

RJ Chenery, A Ayrton, HG Oldham, P Standring, SJ Norman, T Seddon, and R Kirby
Diazepam metabolism in cultured hepatocytes from rat, rabbit, dog, guinea pig, and man
Drug Metab Dispos 1987 15: 312-317. [Abstract] [PDF]  

DC Mays, SG Hecht, SE Unger, CM Pacula, JM Climie, DE Sharp, and N Gerber
Disposition of 8-methoxypsoralen in the rat. Induction of metabolism in vivo and in vitro and identification of urinary metabolites by thermospray mass spectrometry
Drug Metab Dispos 1987 15: 318-328. [Abstract] [PDF]  

MS Engineer, Sr Bodey GP, RA Newman, and DH Ho
Effects of cisplatin-induced nephrotoxicity on gentamicin pharmacokinetics in rats
Drug Metab Dispos 1987 15: 329-334. [Abstract] [PDF]  

JK Ritter and MR Franklin
Induction and inhibition of rat hepatic drug metabolism by N- substituted imidazole drugs
Drug Metab Dispos 1987 15: 335-343. [Abstract] [PDF]  

I Jansson and JB Schenkman
Influence of cytochrome b5 on the stoichiometry of the different oxidative reactions catalyzed by liver microsomal cytochrome P-450
Drug Metab Dispos 1987 15: 344-348. [Abstract] [PDF]  

HA Sasame, DJ Liberato, and JR Gillette
The formation of glutathione conjugate derived from propranolol
Drug Metab Dispos 1987 15: 349-355. [Abstract] [PDF]  

LE Rikans
The oxidation of acrolein by rat liver aldehyde dehydrogenases. Relation to allyl alcohol hepatotoxicity
Drug Metab Dispos 1987 15: 356-362. [Abstract] [PDF]  

LA Gallenberg and MJ Vodicnik
The disposition and elimination of two sequential doses of 2,4,5,2',4',5'-hexachlorobiphenyl
Drug Metab Dispos 1987 15: 363-366. [Abstract] [PDF]  

YM Ioannou, LT Burka, JM Sanders, MP Moorman, and HB Matthews
Absorption, distribution, metabolism, and excretion of 1,2-dihydro- 2,2,4-trimethylquinoline in the male F344 rat
Drug Metab Dispos 1987 15: 367-373. [Abstract] [PDF]  

M Schafer-Korting
Pharmacokinetics of griseofulvin in blood and skin suction blister fluid of rats
Drug Metab Dispos 1987 15: 374-376. [Abstract] [PDF]  

O Wagner, E Schreier, F Heitz, and G Maurer
Tissue distribution, disposition, and metabolism of cyclosporine in rats
Drug Metab Dispos 1987 15: 377-383. [Abstract] [PDF]  

G Fabre, P Bertault-Peres, I Fabre, P Maurel, S Just, and JP Cano
Metabolism of cyclosporin A. I. Study in freshly isolated rabbit hepatocytes
Drug Metab Dispos 1987 15: 384-390. [Abstract] [PDF]  

P Bertault-Peres, C Bonfils, G Fabre, S Just, JP Cano, and P Maurel
Metabolism of cyclosporin A. II. Implication of the macrolide antibiotic inducible cytochrome P-450 3c from rabbit liver microsomes
Drug Metab Dispos 1987 15: 391-398. [Abstract] [PDF]  

M Hassan and H Ehrsson
Urinary metabolites of busulfan in the rat
Drug Metab Dispos 1987 15: 399-402. [Abstract] [PDF]  

S Edsbacker, P Andersson, C Lindberg, J Paulson, A Ryrfeldt, and A Thalen
Liver metabolism of budesonide in rat, mouse, and man. Comparative aspects
Drug Metab Dispos 1987 15: 403-411. [Abstract] [PDF]  

S Edsbacker, P Andersson, C Lindberg, A Ryrfeldt, and A Thalen
Metabolic acetal splitting of budesonide. A novel inactivation pathway for topical glucocorticoids
Drug Metab Dispos 1987 15: 412-417. [Abstract] [PDF]  

CE Zoetemelk, W van Hove, WL van der Laan, B van Meeteren-Walchli, A van der Gen, and DD Breimer
Glutathione conjugation of 1,2-dibromo-1-phenylethane in rats in vivo
Drug Metab Dispos 1987 15: 418-425. [Abstract] [PDF]  

M Koike, R Norikura, S Futaguchi, T Yamaguchi, K Sugeno, K Iwatani, Y Ikenishi, and Y Nakagawa
N-hydroxymethyl metabolites of 450191-S, a 1H-1,2,4,-triazolyl benzophenone derivative, in dog plasma
Drug Metab Dispos 1987 15: 426-428. [Abstract] [PDF]  

WA Colburn, J Hakimi, and I Bekersky
Plasma concentration profiles of human recombinant interleukin-2 (HrIL- 2) in the rat following administration by various systemic routes
Drug Metab Dispos 1987 15: 429-431. [PDF]  

CK Svensson and LL Liu
Dose- and time-dependent effect of levamisole on the elimination of antipyrine in the rat
Drug Metab Dispos 1987 15: 432-434. [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


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