Articles:

MT Baker and JN Bates

Metabolic activation of the halothane metabolite, [14C]2-chloro-1,1- difluoroethene, in hepatic microsomes
Drug Metab Dispos 1988 16: 169-172. [Abstract] [PDF]  

M Shou and SK Yang

Regioselective and stereoselective metabolisms of pyrene and 1- bromopyrene by rat liver microsomes and effects of enzyme inducers
Drug Metab Dispos 1988 16: 173-183. [Abstract] [PDF]  

WL Nelson, LD Olsen, DB Beitner, and RJ Jr Pallow

Regiochemistry and substrate stereoselectivity of O-demethylation of verapamil in the presence of the microsomal fraction from rat and human liver
Drug Metab Dispos 1988 16: 184-188. [Abstract] [PDF]  

JR Stewart and GL Diamond

In vivo renal tubular secretion and metabolism of the disulfide of 2,3- dimercaptopropane-1-sulfonate
Drug Metab Dispos 1988 16: 189-195. [Abstract] [PDF]  

IH Hall, DJ Reynolds, SD Wyrick, JH Maguire, and RP Shrewsbury

The disposition of the hypolipidemic agent, o-(N- phthalimido)acetophenone, in Sprague-Dawley rats
Drug Metab Dispos 1988 16: 196-200. [Abstract] [PDF]  

KL Fong, CS Crysler, BA Mico, KE Boyle, GA Kopia, L Kopaciewicz, and RK Lynn

Dose-dependent pharmacokinetics of recombinant tissue-type plasminogen activator in anesthetized dogs following intravenous infusion
Drug Metab Dispos 1988 16: 201-206. [Abstract] [PDF]  

RE Talaat and WL Nelson

Regioisomeric aromatic dihydroxylation of propranolol. Use of monohydroxylated intermediates for structural assignments of the metabolites formed in vitro
Drug Metab Dispos 1988 16: 207-211. [Abstract] [PDF]  

RE Talaat and WL Nelson

Regioisomeric aromatic dihydroxylation of propranolol. Synthesis and identification of 4,6- and 4,8-dihydroxypropranolol as metabolites in the rat and in man
Drug Metab Dispos 1988 16: 212-216. [Abstract] [PDF]  

LM Gustavson and WL Nelson

Regioisomeric products of propranolol metabolism. The monomethyl ethers of 3,4-dihydroxypropranolol and of 3,4-dihydroxypropranolol glycol
Drug Metab Dispos 1988 16: 217-221. [Abstract] [PDF]  

WH Wu, BM Henderson, R Lanc, D Garnes, A Yacobi, and BM Silber

Relationship between the pharmacokinetic and pharmacodynamic profile of nilvadipine in the dog
Drug Metab Dispos 1988 16: 222-227. [Abstract] [PDF]  

R Kannan and A Matin-Asgari

Dose-dependent tissue uptake of flecainide during chronic administration in rabbits
Drug Metab Dispos 1988 16: 228-231. [Abstract] [PDF]  

PE Weller, N Narasimhan, JA Buben, and RP Hanzlik

In vitro metabolism and covalent binding among ortho-substituted bromobenzenes of varying hepatotoxicity
Drug Metab Dispos 1988 16: 232-237. [Abstract] [PDF]  

JG Dain and JM Jaffe

Effect of diet and gavage on the absorption and metabolism of fluperlapine in the rat
Drug Metab Dispos 1988 16: 238-242. [Abstract] [PDF]  

DA Wells and GA Digenis

Disposition and metabolism of double-labeled [3H and 14C] N-methyl-2- pyrrolidinone in the rat
Drug Metab Dispos 1988 16: 243-249. [Abstract] [PDF]  

D Di Monte, T Shinka, MS Sandy, N Jr Castagnoli, and MT Smith

Quantitative analysis of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolism in isolated rat hepatocytes
Drug Metab Dispos 1988 16: 250-255. [Abstract] [PDF]  

MJ D'Souza, SH Pollock, and HM Solomon

Cyclosporine-phenytoin interaction
Drug Metab Dispos 1988 16: 256-258. [Abstract] [PDF]  

DI Papac and MR Franklin

N-benzylimidazole, a high magnitude inducer of rat hepatic cytochrome P- 450 exhibiting both polycyclic aromatic hydrocarbon- and phenobarbital- type induction of phase I and phase II drug-metabolizing enzymes
Drug Metab Dispos 1988 16: 259-264. [Abstract] [PDF]  

XX Ding and MJ Coon

Cytochrome P-450-dependent formation of ethylene from N- nitrosoethylamines
Drug Metab Dispos 1988 16: 265-269. [Abstract] [PDF]  

BL Ferraiolo, JA Moore, D Crase, P Gribling, H Wilking, and RA Baughman

Pharmacokinetics and tissue distribution of recombinant human tumor necrosis factor-alpha in mice
Drug Metab Dispos 1988 16: 270-275. [Abstract] [PDF]  

A Pfeifer and HG Neumann

Modulation of trans-4-acetylaminostilbene metabolism in the rat by methylcholanthrene and phenobarbital and its relevance for acute toxicity
Drug Metab Dispos 1988 16: 276-284. [Abstract] [PDF]  

BM Frey, M Sieber, D Mettler, H Ganger, and FJ Frey

Marked interspecies differences between humans and pigs in cyclosporine and prednisolone disposition
Drug Metab Dispos 1988 16: 285-289. [Abstract] [PDF]  

TH Lin, Y Sugiyama, Y Sawada, S Kawasaki, T Iga, and M Hanano

Effect of serum from renal failure and cirrhotic patients on the blood- brain barrier permeability to DL-propranolol in rats
Drug Metab Dispos 1988 16: 290-295. [Abstract] [PDF]  

I Fabre, G Fabre, P Maurel, P Bertault-Peres, and JP Cano

Metabolism of cyclosporin A. III. Interaction of the macrolide antibiotic, erythromycin, using rabbit hepatocytes and microsomal fractions
Drug Metab Dispos 1988 16: 296-301. [Abstract] [PDF]  

A Weil, J Caldwell, and M Strolin-Benedetti

The metabolism and disposition of fenofibrate in rat, guinea pig, and dog
Drug Metab Dispos 1988 16: 302-309. [Abstract] [PDF]  

I de Waziers, M Boisset, and S Atteba

Pre- and postweaning development of drug-metabolizing enzyme activities in small intestine and liver of rats
Drug Metab Dispos 1988 16: 310-315. [Abstract] [PDF]  

Y Braham, G Meunier, and B Meunier

The rat biliary and urinary metabolism of the N6-methylated derivative of elliptinium acetate, and antitumor agent
Drug Metab Dispos 1988 16: 316-321. [Abstract] [PDF]  

ML Hyneck, A Munafo, and LZ Benet

Effect of pH on acyl migration and hydrolysis of tolmetin glucuronide
Drug Metab Dispos 1988 16: 322-324. [PDF]  

H Kim, B Pramanik, A Lapiguera, TM Chan, VM Girijavallabhan, S Symchowicz, and C Lin

Identification of two metabolites of a penem (Sch 34343) in human urine
Drug Metab Dispos 1988 16: 325-327. [PDF]  

H Suzuki, Y Sawada, Y Sugiyama, T Iga, and M Hanano

Efflux of cimetidine from the rat cerebrospinal fluid
Drug Metab Dispos 1988 16: 328-330. [PDF]  

LG Gisclon and KM Giacomini

Inhibition of cimetidine transport by creatinine in luminal membrane vesicles prepared from rabbit kidney
Drug Metab Dispos 1988 16: 331-332. [PDF]  

SJ Glass and RB van Lier

Metabolism of 7-ethoxyresorufin by phenobarbital or Aroclor 1254 pretreated mice [see comments]
Drug Metab Dispos 1988 16: 333-334. [PDF]  

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