Articles:

DJ Tocco, FA deLuna, AE Duncan, JH Hsieh, and JH Lin

Interspecies differences in stereoselective protein binding and clearance of MK-571
Drug Metab Dispos 1990 18: 388-392. [Abstract] [PDF]  

LA Clejan and AI Cederbaum

Comparison of the interaction of pyrazole and its metabolite 4- hydroxypyrazole with rat liver microsomes
Drug Metab Dispos 1990 18: 393-397. [Abstract] [PDF]  

J Schulze, E Richter, and RM Philpot

Tissue, species, and substrate concentration differences in the position-selective hydroxylation of N-nitrosodibutylamine. Relationship to the distribution of cytochrome P-450 isozymes 2 (IIB) and 5 (IVB)
Drug Metab Dispos 1990 18: 398-402. [Abstract] [PDF]  

R Murata, DB Haughey, and WJ Jusko

Effects of thyroid dysfunction on prednisolone and prednisone interconversion and disposition in the rat
Drug Metab Dispos 1990 18: 403-408. [Abstract] [PDF]  

S Aoyama and K Kamata

Metabolic fate of alclometasone dipropionate in rats, rabbits, and mice. Metabolic products and pathway following subcutaneous administration
Drug Metab Dispos 1990 18: 409-417. [Abstract] [PDF]  

DE Williams, MK Shigenaga, and N Jr Castagnoli

The role of cytochromes P-450 and flavin-containing monooxygenase in the metabolism of (S)-nicotine by rabbit lung
Drug Metab Dispos 1990 18: 418-428. [Abstract] [PDF]  

D Smith, W Aldrich, M Dey, R Enever, R Warner, and R Weierstall

A pharmacokinetic model for isosorbidedinitrate, isosorbide-2- mononitrate, and isosorbide-5-mononitrate
Drug Metab Dispos 1990 18: 429-434. [Abstract] [PDF]  

RK Brazzell, YH Park, CB Wooldridge, B McCue, R Barker, R Couch, and B York

Interspecies comparison of the pharmacokinetics of aldose reductase inhibitors
Drug Metab Dispos 1990 18: 435-440. [Abstract] [PDF]  

JL Ferrero, BA Bopp, KC Marsh, SC Quigley, MJ Johnson, DJ Anderson, JE Lamm, KG Tolman, SW Sanders, and JH Cavanaugh

Metabolism and disposition of clarithromycin in man
Drug Metab Dispos 1990 18: 441-446. [Abstract] [PDF]  

AJ Streeter, RW Nims, PR Sheffels, JA Hrabie, L Ohannesian, YH Heur, BA Mico, and LK Keefer

Deuterium isotope effect on the toxicokinetics of monomethylamine in the rat
Drug Metab Dispos 1990 18: 447-452. [Abstract] [PDF]  

SY Yeh

N-depyridination and N-dedimethylaminoethylation of tripelennamine and pyrilamine in the rat. New metabolic pathways
Drug Metab Dispos 1990 18: 453-461. [Abstract] [PDF]  

Y Kumagai, T Todaka, S Yamano, and S Toki

Stimulation mechanism of guinea pig liver-mediated reduction of naloxone by morphine
Drug Metab Dispos 1990 18: 462-466. [Abstract] [PDF]  

C Pous, JP Giroud, C Damais, D Raichvarg, and L Chauvelot-Moachon

Effect of recombinant human interleukin-1 beta and tumor necrosis factor alpha on liver cytochrome P-450 and serum alpha-1-acid glycoprotein concentrations in the rat
Drug Metab Dispos 1990 18: 467-470. [Abstract] [PDF]  

DR Brocks and F Jamali

The pharmacokinetics of etodolac enantiomers in the rat. Lack of pharmacokinetic interaction between enantiomers
Drug Metab Dispos 1990 18: 471-475. [Abstract] [PDF]  

S Vickers, CA Duncan, KP Vyas, PH Kari, B Arison, SR Prakash, HG Ramjit, SM Pitzenberger, G Stokker, and DE Duggan

In vitro and in vivo biotransformation of simvastatin, an inhibitor of HMG CoA reductase
Drug Metab Dispos 1990 18: 476-483. [Abstract] [PDF]  

JH Lin, FA deLuna, EH Ulm, and DJ Tocco

Species-dependent enantioselective plasma protein binding of MK-571, a potent leukotriene D4 antagonist
Drug Metab Dispos 1990 18: 484-487. [Abstract] [PDF]  

WT Brashear, BR Kuhnert, and R Wei

Structural determination of the conjugated metabolites of ritodrine
Drug Metab Dispos 1990 18: 488-493. [Abstract] [PDF]  

TF McMahon, JJ Diliberto, and LS Birnbaum

Effects of age and dose on disposition and metabolism of salicylic acid in male Fischer 344 rats
Drug Metab Dispos 1990 18: 494-503. [Abstract] [PDF]  

N Kurata, R Kemper, HE Hurst, and WJ Waddell

Inhibition of the metabolism of ethyl carbamate by acetaldehyde
Drug Metab Dispos 1990 18: 504-507. [Abstract] [PDF]  

RS Obach and H van Vunakis

Radioimmunoassay of nicotine-delta 1'(5')-iminium ion, an intermediate formed during the metabolism of nicotine to cotinine [published erratum appears in Drug Metab Dispos Biol Fate Chem 1991 Jan-Feb;19(1):289]
Drug Metab Dispos 1990 18: 508-513. [Abstract] [PDF]  

HN Ghantous, J Fernando, AJ Gandolfi, and K Brendel

Biotransformation of halothane in guinea pig liver slices
Drug Metab Dispos 1990 18: 514-518. [Abstract] [PDF]  

BS Donahue and ET Morgan

Effects of vanadate on hepatic cytochrome P-450 expression in streptozotocin-diabetic rats
Drug Metab Dispos 1990 18: 519-526. [Abstract] [PDF]  

SM Sanins, WJ Adams, DG Kaiser, GW Halstead, and TA Baillie

Studies on the metabolism and chiral inversion of ibuprofen in isolated rat hepatocytes
Drug Metab Dispos 1990 18: 527-533. [Abstract] [PDF]  

PG Forkert, BA Geddes, DW Birch, and TE Massey

Morphologic changes and covalent binding of 1,1-dichloroethylene in Clara and alveolar type II cells isolated from lungs of mice following in vivo administration
Drug Metab Dispos 1990 18: 534-539. [Abstract] [PDF]  

BM Kerr and RH Levy

Unsubstituted amides: new class of potent inhibitors of human microsomal epoxide hydrolase
Drug Metab Dispos 1990 18: 540-542. [PDF]  

DA Staats, DP Lohr, and HD Colby

Effects of carbon tetrachloride administration to guinea pigs on cytochromes P-450 and antioxidant levels in the inner and outer zones of the adrenal cortex
Drug Metab Dispos 1990 18: 543-545. [PDF]  

SY Brown, WA Garland, and EK Fukuda

Isolation and characterization of an unusual glucuronide conjugate of rimantadine
Drug Metab Dispos 1990 18: 546-547. [PDF]  

E Samara, NK Brown, and DJ Harvey

Microsomal metabolism of the 1",1"-dimethylheptyl analogue of cannabidiol: relative percentage of monohydroxy metabolites in four species
Drug Metab Dispos 1990 18: 548-549. [PDF]  

Letters:

J Mordenti

Comment: Pharmaceutics of acetaminophen, vancomycin, and antipyrine on the Hanford miniature swine [letter; comment]
Drug Metab Dispos 1990 18: 387. [PDF]  

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