Articles:

SM Plakas and MO James

Bioavailability, metabolism, and renal excretion of benzoic acid in the channel catfish (Ictalurus punctatus)
Drug Metab Dispos 1990 18: 552-556. [Abstract] [PDF]  

K Nagata, BM Martin, JR Gillette, and HA Sasame

Isozymes of cytochrome P-450 that metabolize naphthalene in liver and lung of untreated mice
Drug Metab Dispos 1990 18: 557-564. [Abstract] [PDF]  

M Nadai, H Yoshizumi, T Kuzuya, T Hasegawa, I Johno, and S Kitazawa

Effect of diabetes on disposition and renal handling of cefazolin in rats
Drug Metab Dispos 1990 18: 565-570. [Abstract] [PDF]  

E Samara, M Bialer, and DJ Harvey

Identification of urinary metabolites of cannabidiol in the dog
Drug Metab Dispos 1990 18: 571-579. [Abstract] [PDF]  

H Hirayama and KS Pang

First-pass metabolism of gentisamide: influence of intestinal metabolism on hepatic formation of conjugates. Studies in the once- through vascularly perfused rat intestine-liver preparation
Drug Metab Dispos 1990 18: 580-587. [Abstract] [PDF]  

H Hirayama, J Morgado, I Gasinska, and KS Pang

Estimations of intestinal and liver first-pass metabolism in vivo. Studies on gentisamide conjugation in the rat
Drug Metab Dispos 1990 18: 588-594. [Abstract] [PDF]  

L Pichard, I Fabre, G Fabre, J Domergue, B Saint Aubert, G Mourad, and P Maurel

Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes
Drug Metab Dispos 1990 18: 595-606. [Abstract] [PDF]  

MO Howard, JF Newton, DJ Keohane, LP Yodis, CM Saverino, CW Jr Qualls, and LW Schwartz

In vitro metabolism of the novel antiinflammatory agent 6-(4'- fluorophenyl)-5-(4'-pyridyl)-2,3-dihydroimidazo-[2,1-b]-thiazole
Drug Metab Dispos 1990 18: 607-612. [Abstract] [PDF]  

DG Walker, M Hutchison, TA Shepard, PM Osborne, SM Allenby, AJ Webb, NJ Viney, MA Pue, RJ Chenery, and PJ Wood

The disposition of 2-cyano-1-methyl 3-(4-(4-methyl-6-oxo-1,4,5,6- tetrahydro-pyridazin-3-yl)phenyl)guanidine in animals
Drug Metab Dispos 1990 18: 613-620. [Abstract] [PDF]  

A Hisaka, S Kasamatsu, N Takenaga, and M Ohtawa

Absorption of a novel prodrug of L-dopa, L-3-(3-hydroxy-4- pivaloyloxyphenyl)alanine (NB-355). In vitro and in situ studies
Drug Metab Dispos 1990 18: 621-625. [Abstract] [PDF]  

GW Harrington, PN Magee, HM Jr Pylypiw, R Kozeniauskas, RF Bevill, DR Nelson, and JC Thurmon

The formation, disposition, and hepatic metabolism of dimethylnitrosamine in the pig
Drug Metab Dispos 1990 18: 626-631. [Abstract] [PDF]  

JA Van Loon and RM Weinshilboum

Thiopurine methyltransferase isozymes in human renal tissue
Drug Metab Dispos 1990 18: 632-638. [Abstract] [PDF]  

PC Smith, LZ Benet, and AF McDonagh

Covalent binding of zomepirac glucuronide to proteins: evidence for a Schiff base mechanism
Drug Metab Dispos 1990 18: 639-644. [Abstract] [PDF]  

PC Ruenitz and NT Nanavati

Identification and distribution in the rat of acidic metabolites of tamoxifen
Drug Metab Dispos 1990 18: 645-648. [Abstract] [PDF]  

ET Morgan and CA Norman

Pretranslational suppression of cytochrome P-450h (IIC11) gene expression in rat liver after administration of interferon inducers
Drug Metab Dispos 1990 18: 649-653. [Abstract] [PDF]  

GF Ray, WD Mason, and MZ Badr

Pharmacokinetics of the anti-AIDS drug 2',3'-dideoxyinosine in the rat
Drug Metab Dispos 1990 18: 654-658. [Abstract] [PDF]  

TA Smolarek, CV Higgins, and DE Amacher

Metabolism and cytotoxicity of acetaminophen in hepatocyte cultures from rat, rabbit, dog, and monkey
Drug Metab Dispos 1990 18: 659-663. [Abstract] [PDF]  

SR Myers and JW Flesher

Metabolism of the carcinogen 3-methylcholanthrene in human bone marrow preparations
Drug Metab Dispos 1990 18: 664-669. [Abstract] [PDF]  

J Shah and WD Mason

Pharmacokinetics of codeine after parenteral and oral dosing in the rat
Drug Metab Dispos 1990 18: 670-673. [Abstract] [PDF]  

KJ Ruterbories and TD Lindstrom

Pharmacokinetics of a novel butylated hydroxytoluene-thiazolidinone CNS antiischemic agent LY256548 in rats, mice, dogs, and monkeys
Drug Metab Dispos 1990 18: 674-679. [Abstract] [PDF]  

F Ogolla, RJ Ferguson, WG Kirlin, A Trinidad, AF Andrews, M Mpezo, and DW Hein

Acetylator genotype-dependent expression of arylamine N- acetyltransferase and N-hydroxyarylamine O-acetyltransferase in Syrian inbred hamster intestine and colon. Identity with the hepatic acetylation polymorphism
Drug Metab Dispos 1990 18: 680-685. [Abstract] [PDF]  

AK Cho, M Hiramatsu, EW Distefano, AS Chang, and DJ Jenden

Stereochemical differences in the metabolism of 3,4- methylenedioxymethamphetamine in vivo and in vitro: a pharmacokinetic analysis
Drug Metab Dispos 1990 18: 686-691. [Abstract] [PDF]  

J Magdalou, V Chajes, C Lafaurie, and G Siest

Glucuronidation of 2-arylpropionic acids pirprofen, flurbiprofen, and ibuprofen by liver microsomes
Drug Metab Dispos 1990 18: 692-697. [Abstract] [PDF]  

M Tanaka, K Ono, H Hakusui, T Takegoshi, Y Watanabe, and M Kanao

Identification of DP-1904 and its ester glucuronide in human urine and determination of their enantiomeric compositions by high-performance liquid chromatography with optical activity and ultraviolet detection
Drug Metab Dispos 1990 18: 698-703. [Abstract] [PDF]  

K Lavrijsen, J Van Houdt, D Van Dyck, J Hendrickx, W Lauwers, R Hurkmans, M Bockx, C Janssen, W Meuldermans, and J Heykants

Biotransformation of sufentanil in liver microsomes of rats, dogs, and humans
Drug Metab Dispos 1990 18: 704-710. [Abstract] [PDF]  

L Pichard, G Gillet, I Fabre, I Dalet-Beluche, C Bonfils, JP Thenot, and P Maurel

Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem
Drug Metab Dispos 1990 18: 711-719. [Abstract] [PDF]  

D Schrenk and KW Bock

Metabolism of benzene in rat hepatocytes. Influence of inducers on phenol glucuronidation
Drug Metab Dispos 1990 18: 720-725. [Abstract] [PDF]  

JW Cox, LG Dring, LC Ginsberg, PG Larson, DA Constable, and RG Ulrich

Distribution and disposition of trospectomycin sulfate in the in vivo rat, perfused rat liver, and cultured rat hepatocytes
Drug Metab Dispos 1990 18: 726-731. [Abstract] [PDF]  

IG Alonso, JM Lanao, MI Martin, A Mateos, A Dominguez-Gil Hurle, and J Fermoso

Influence of a single dose of ethanol on the kinetics of valproic acid in rats
Drug Metab Dispos 1990 18: 732-734. [Abstract] [PDF]  

YZ Shu, JW Hubbard, JK Cooper, G McKay, ED Korchinski, R Kumar, and KK Midha

The identification of urinary metabolites of doxepin in patients
Drug Metab Dispos 1990 18: 735-741. [Abstract] [PDF]  

XX Ding and MJ Coon

Induction of cytochrome P-450 isozyme 3a (P-450IIE1) in rabbit olfactory mucosa by ethanol and acetone
Drug Metab Dispos 1990 18: 742-745. [Abstract] [PDF]  

JA Scatina, DS Wells, HB Kimmel, CJ Kemper, and SF Sisenwine

Excretion and metabolism of recainam, a new anti-arrhythmic drug, in laboratory animals and humans
Drug Metab Dispos 1990 18: 746-752. [Abstract] [PDF]  

MT Baker, MT Vasquez, JN Bates, and CK Chiang

Metabolism of 2-chloro-1,1-difluoroethene to glyoxylic and glycolic acid in rat hepatic microsomes
Drug Metab Dispos 1990 18: 753-758. [Abstract] [PDF]  

RJ Bjercke, DK Hammond, HW Strobel, and JJ Langone

Interaction of cotinine with rat hepatic microsomal P-450. Comparison with metyrapone and immunomodulation of cotinine and metyrapone binding by monoclonal anti-cotinine antibodies
Drug Metab Dispos 1990 18: 759-764. [Abstract] [PDF]  

MS Rashed, TG Myers, and SD Nelson

Hepatic protein arylation, glutathione depletion, and metabolite profiles of acetaminophen and a non-hepatotoxic regioisomer, 3'- hydroxyacetanilide, in the mouse
Drug Metab Dispos 1990 18: 765-770. [Abstract] [PDF]  

O Caputo, G Grosa, M Ceruti, F Rocco, and G Biglino

Metabolism of 1,1-dichloro-cis-diphenylcyclopropane by rat liver microsomes
Drug Metab Dispos 1990 18: 771-778. [Abstract] [PDF]  

RS Hsu, GM Shutske, EM Dileo, SM Chesson, AR Linville, and RC Allen

Identification of the urinary metabolites of tacrine in the rat
Drug Metab Dispos 1990 18: 779-783. [Abstract] [PDF]  

AE Cribb and SP Spielberg

Hepatic microsomal metabolism of sulfamethoxazole to the hydroxylamine
Drug Metab Dispos 1990 18: 784-787. [Abstract] [PDF]  

JG Kenna, JL Martin, H Satoh, and LR Pohl

Factors affecting the expression of trifluoroacetylated liver microsomal protein neoantigens in rats treated with halothane
Drug Metab Dispos 1990 18: 788-793. [Abstract] [PDF]  

L Grislain, P Gele, M Bertrand, W Luijten, N Bromet, C Salvadori, and A Kamoun

The metabolic pathways of tianeptine, a new antidepressant, in healthy volunteers
Drug Metab Dispos 1990 18: 804-808. [Abstract] [PDF]  

ME Morris

Pharmacokinetics and protein binding of salicylate metabolites in rats
Drug Metab Dispos 1990 18: 809-811. [PDF]  

S Fujita, J Tatsuno, K Kitani, and T Suzuki

Age-associated alterations in diazepam metabolizing enzyme activities in male and female rats
Drug Metab Dispos 1990 18: 812-814. [PDF]  

TL Chen, PS Miller, PO Ts'o, OM Colvin, and TL] Chem TL$[corrected to Chen

Disposition and metabolism of oligodeoxynucleoside methylphosphonate following a single i.v. injection in mice [published erratum appears in Drug Metab Dispos Biol Fate Chem 1991 Nov-Dec;19(6):1165]
Drug Metab Dispos 1990 18: 815-818. [PDF]  

MA Jenner, JL Plummer, and MJ Cousins

Influence of isoniazid, phenobarbital, phenytoin, pregnenolone 16-alpha carbonitrile, and beta-naphthoflavone on halothane metabolism and hepatotoxicity
Drug Metab Dispos 1990 18: 819-822. [PDF]  

Letters:

M Paolini, GC Forti, and C Bauer

Expressing the specificity and the potency of cytochrome P-450 inducers toward 7-ethoxyresorufin [letter; comment]
Drug Metab Dispos 1990 18: 551. [PDF]  

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