Articles:

PS Hong, A Srigritsanapol, and KK Chan

Pharmacokinetics of 4-hydroxycyclophosphamide and metabolites in the rat
Drug Metab Dispos 1991 19: 1-7. [Abstract] [PDF]  

SH Steiner, MJ Moor, and MH Bickel

Kinetics of distribution and adipose tissue storage as a function of lipophilicity and chemical structure. I. Barbiturates
Drug Metab Dispos 1991 19: 8-14. [Abstract] [PDF]  

X Xie, SH Steiner, and MH Bickel

Kinetics of distribution and adipose tissue storage as a function of lipophilicity and chemical structure. II. Benzodiazepines
Drug Metab Dispos 1991 19: 15-19. [Abstract] [PDF]  

NR Niemeijer, TK Gerding, and RA De Zeeuw

Glucuronidation of labetalol at the two hydroxy positions by bovine liver microsomes. Isolation, purification, and structure elucidation of the glucuronides of labetalol
Drug Metab Dispos 1991 19: 20-23. [Abstract] [PDF]  

PR Pentel, DE Keyler, GJ Brunn, JM Milavetz, DG Gilbertson, SG Matta, and SM Pond

Redistribution of tricyclic antidepressants in rats using a drug- specific monoclonal antibody: dose-response relationship
Drug Metab Dispos 1991 19: 24-28. [Abstract] [PDF]  

W Krause, F Reissmann, W Schunack, and C Schobel

Comparative pharmacokinetics of abecarnil in rat following single and multiple intragastric treatment and continuous administration via the diet
Drug Metab Dispos 1991 19: 29-35. [Abstract] [PDF]  

SP Robinson, SM Langan-Fahey, DA Johnson, and VC Jordan

Metabolites, pharmacodynamics, and pharmacokinetics of tamoxifen in rats and mice compared to the breast cancer patient
Drug Metab Dispos 1991 19: 36-43. [Abstract] [PDF]  

D Garteiz, ZH Siddik, and RA Newman

In vitro and in vivo murine metabolism of spirogermanium
Drug Metab Dispos 1991 19: 44-47. [Abstract] [PDF]  

EJ Holsztynska, WW Weber, and EF Domino

Genetic polymorphism of cytochrome P-450-dependent phencyclidine hydroxylation in mice. Comparison of phencyclidine hydroxylation in humans
Drug Metab Dispos 1991 19: 48-53. [Abstract] [PDF]  

BM Manzione, JR Bernstein, and RB Franklin

Observations on the absorption, distribution, metabolism, and excretion of the dopamine (D2) agonist, quinelorane, in rats, mice, dogs, and monkeys
Drug Metab Dispos 1991 19: 54-60. [Abstract] [PDF]  

JH Satterwhite and FD Boudinot

Effects of age and dose on the pharmacokinetics of ibuprofen in the rat
Drug Metab Dispos 1991 19: 61-67. [Abstract] [PDF]  

RH Barbhaiya, CA Knupp, ST Forgue, GR Matzke, CE Halstenson, JA Opsahl, and KA Pittman

Disposition of the cephalosporin cefepime in normal and renally impaired subjects
Drug Metab Dispos 1991 19: 68-73. [Abstract] [PDF]  

BB Hasinoff, FX Reinders, and V Clark

The enzymatic hydrolysis-activation of the adriamycin cardioprotective agent (+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane
Drug Metab Dispos 1991 19: 74-80. [Abstract] [PDF]  

CS Boyer and DR Petersen

The metabolism of 3,7-dimethyl-2,6-octadienal (citral) in rat hepatic mitochondrial and cytosolic fractions. Interactions with aldehyde and alcohol dehydrogenases
Drug Metab Dispos 1991 19: 81-86. [Abstract] [PDF]  

VG Hale and LZ Benet

Prednisolone and prednisone exhibit linear extraction in the perfused rabbit liver
Drug Metab Dispos 1991 19: 87-93. [Abstract] [PDF]  

JC Maurizis, C Nicolas, M Verny, M Ollier, M Faurie, M Payard, and A Veyre

Biodistribution and metabolism in rats and mice of bucromarone
Drug Metab Dispos 1991 19: 94-99. [Abstract] [PDF]  

KN Gan, A Smolen, HW Eckerson, and BN La Du

Purification of human serum paraoxonase/arylesterase. Evidence for one esterase catalyzing both activities
Drug Metab Dispos 1991 19: 100-106. [Abstract] [PDF]  

A Smolen, HW Eckerson, KN Gan, N Hailat, and BN La Du

Characteristics of the genetically determined allozymic forms of human serum paraoxonase/arylesterase
Drug Metab Dispos 1991 19: 107-112. [Abstract] [PDF]  

RM Smolowitz, ME Hahn, and JJ Stegeman

Immunohistochemical localization of cytochrome P-450IA1 induced by 3,3',4,4'-tetrachlorobiphenyl and by 2,3,7,8-tetrachlorodibenzoafuran in liver and extrahepatic tissues of the teleost Stenotomus chrysops (scup)
Drug Metab Dispos 1991 19: 113-123. [Abstract] [PDF]  

MS Bogdanffy, CR Kee, CA Hinchman, and BA Trela

Metabolism of dibasic esters by rat nasal mucosal carboxylesterase
Drug Metab Dispos 1991 19: 124-129. [Abstract] [PDF]  

GM Pollack, JL Browne, J Marton, and LJ Haberer

Chronic stress impairs oxidative metabolism and hepatic excretion of model xenobiotic substrates in the rat
Drug Metab Dispos 1991 19: 130-134. [Abstract] [PDF]  

JE Estep, MW Lame, D Morin, AD Jones, DW Wilson, and HJ Segall

[14C]monocrotaline kinetics and metabolism in the rat
Drug Metab Dispos 1991 19: 135-139. [Abstract] [PDF]  

GF Bories, EF Perdu-Durand, JF Sutra, and JE Tulliez

Evidence for glucuronidation and sulfation of zeranol and metabolites (taleranol and zearalanone) by rat and pig hepatic subfractions
Drug Metab Dispos 1991 19: 140-143. [Abstract] [PDF]  

DA Staats, JW Fisher, and RB Connolly

Gastrointestinal absorption of xenobiotics in physiologically based pharmacokinetic models. A two-compartment description
Drug Metab Dispos 1991 19: 144-148. [Abstract] [PDF]  

MW Sinz and RP Remmel

Isolation and characterization of a novel quaternary ammonium-linked glucuronide of lamotrigine
Drug Metab Dispos 1991 19: 149-153. [Abstract] [PDF]  

YZ Shu, JW Hubbard, G McKay, EM Hawes, and KK Midha

Cis-flupentixol metabolites in rat plasma and bile. The first proof of glutathione conjugation at the exocyclic double bond
Drug Metab Dispos 1991 19: 154-162. [Abstract] [PDF]  

MG Barron, SC Hansen, and T Ball

Pharmacokinetics and metabolism of triclopyr in the crayfish (Procambarus clarki)
Drug Metab Dispos 1991 19: 163-167. [Abstract] [PDF]  

G Veereman-Wauters, J Monbaliu, W Meuldermans, R Woestenborghs, M Verlinden, J Heykants, and CD Rudolph

Study of the placental transfer of cisapride in sheep. Plasma levels in the pregnant ewe, the fetus, and the lamb
Drug Metab Dispos 1991 19: 168-172. [Abstract] [PDF]  

YM Irshaid, A Radominska, P Zimniak, A Zimniak, R Lester, and TR Tephly

Glucuronidation of monohydroxylated short chain bile acids by human liver microsomes and purified human liver UDP-glucuronosyltransferases
Drug Metab Dispos 1991 19: 173-177. [Abstract] [PDF]  

J Taskinen, T Wikberg, P Ottoila, L Kanner, T Lotta, A Pippuri, and R Backstrom

Identification of major metabolites of the catechol-O-methyltransferase- inhibitor nitecapone in human urine
Drug Metab Dispos 1991 19: 178-183. [Abstract] [PDF]  

RJ Keller and JA Hinson

Mechanism of acetaminophen-stimulated NADPH oxidation catalyzed by the peroxidase-H2O2 system
Drug Metab Dispos 1991 19: 184-187. [Abstract] [PDF]  

CJ Jackson, JW Hubbard, G McKay, JK Cooper, EM Hawes, and KK Midha

Identification of phase-I and phase-II metabolites of fluphenazine in rat bile. Intact glucuronide and sulfate conjugates
Drug Metab Dispos 1991 19: 188-193. [Abstract] [PDF]  

S Marleau, TT Nguyen, P Du Souich, M Bellemare, A De Lean, and H Ong

Role of the endopeptidase 24.11 in the disposition and metabolism of endogenous atrial natriuretic factor in the rabbit
Drug Metab Dispos 1991 19: 194-199. [Abstract] [PDF]  

H Tanaka and T Kaneko

Pharmacokinetics of recombinant human granulocyte colony-stimulating factor in the rat. Single and multiple dosing studies
Drug Metab Dispos 1991 19: 200-204. [Abstract] [PDF]  

RO Manning, JV Bruckner, ME Mispagel, and JM Bowen

Metabolism and disposition of sulfluramid, a unique polyfluorinated insecticide, in the rat
Drug Metab Dispos 1991 19: 205-211. [Abstract] [PDF]  

H Cheng, JD Stuhler, BR Dorrbecker, and WP Gordon

Disposition and metabolism of the angiotensin-converting enzyme inhibitor [4S-[4 alpha, 7 alpha, (R*), 12b beta]]-7-[S-(1- ethoxycarbonyl-3- phenylpropyl)amino]-1,2,3,4,6,7,8,12b-octahydro-6-oxo- pyrido[2,1-a][2]benzazepine-4-carboxylic acid in monkeys and dogs
Drug Metab Dispos 1991 19: 212-217. [Abstract] [PDF]  

K Watanabe, N Hirahashi, S Narimatsu, I Yamamoto, and H Yoshimura

Mouse hepatic microsomal enzyme that catalyzes oxidation of 11-oxo- delta 8-tetrahydrocannabinol to delta 8-tetrahydrocannabinol-11-oic acid
Drug Metab Dispos 1991 19: 218-221. [Abstract] [PDF]  

U Hofmann, M Eichelbaum, S Seefried, and CO Meese

Identification of thiodiglycolic acid, thiodiglycolic acid sulfoxide, and (3-carboxymethylthio)lactic acid as major human biotransformation products of S-carboxymethyl-L-cysteine
Drug Metab Dispos 1991 19: 222-226. [Abstract] [PDF]  

KW DiBiasio, MH Silva, LR Shull, JW Overstreet, BD Hammock, and MG Miller

Xenobiotic metabolizing enzyme activities in rat, mouse, monkey, and human testes
Drug Metab Dispos 1991 19: 227-232. [Abstract] [PDF]  

JH Lin, EH Ulm, and LE Los

Dose-dependent stereopharmacokinetics of 5,6-dihydro-4H- 4(isobutylamino)thieno(2,3-B)thiopyran-2-sulfonamide-7,7 -dioxide , a potent carbonic anhydrase inhibitor, in rats
Drug Metab Dispos 1991 19: 233-238. [Abstract] [PDF]  

N Kurata, HE Hurst, RA Kemper, and WJ Waddell

Studies on induction of metabolism of ethyl carbamate in mice by ethanol
Drug Metab Dispos 1991 19: 239-240. [Abstract] [PDF]  

PM Belanger, M Desgagne, and B Bruguerolle

Temporal variations in microsomal lipid peroxidation and in glutathione concentration of rat liver
Drug Metab Dispos 1991 19: 241-244. [Abstract] [PDF]  

PA Cleveland, S Teller, V Kachevsky, E Pinili, R Evans, and MW Modi

Dose-dependent and time-dependent pharmacokinetics in the dog after intravenous administration of dextrorphan
Drug Metab Dispos 1991 19: 245-250. [Abstract] [PDF]  

RJ Guttendorf, HB Kostenbauder, and PJ Wedlund

Stereoselective differences in propranolol disposition in female Sprague-Dawley and Dark Agouti rats
Drug Metab Dispos 1991 19: 251-256. [Abstract] [PDF]  

K Kikuchi, Y Nagatsu, Y Makino, T Mashino, S Ohta, and M Hirobe

Metabolism and penetration through blood-brain barrier of parkinsonism- related compounds. 1,2,3,4-Tetrahydroisoquinoline and 1-methyl-1,2,3,4- tetrahydroisoquinoline
Drug Metab Dispos 1991 19: 257-262. [Abstract] [PDF]  

JG Supko and L Malspeis

Characterization of the urinary metabolites of merbarone in cancer patients
Drug Metab Dispos 1991 19: 263-273. [Abstract] [PDF]  

YS Gietl and MW Anders

Biosynthesis and biliary excretion of S-conjugates of hexachlorobuta- 1,3-diene in the perfused rat liver
Drug Metab Dispos 1991 19: 274-277. [Abstract] [PDF]  

HO Hallak and PJ Wedlund

Vitamin K epoxide reductase activity and its inhibition by warfarin in young and old rats
Drug Metab Dispos 1991 19: 278-279. [PDF]  

MP Knadler and SD Hall

Stereoselective hydrolysis of flurbiprofen conjugates
Drug Metab Dispos 1991 19: 280-282. [PDF]  

CL Woodard and BJ Lukey

MMB-4 pharmacokinetics in rabbits after intravenous and intramuscular administration
Drug Metab Dispos 1991 19: 283-284. [PDF]  

GC Daher, RW Zhang, SJ Soong, and RB Diasio

Circadian variation of fluoropyrimidine catabolic enzymes in rat liver: possible relevance to 5-fluorodeoxyuridine chemotherapy
Drug Metab Dispos 1991 19: 285-287. [PDF]  

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