Articles:

H Shimeno, A Toda, S Ogata, and A Nagamatsu

Purification and aminopyrine monooxygenase activity of liver microsomal cytochrome P-450 from alloxan-induced diabetic rats
Drug Metab Dispos 1991 19: 291-297. [Abstract] [PDF]  

MJ Olson, SG Kim, CA Reidy, JT Johnson, and RF Novak

Oxidation of 1,1,1,2-tetrafluoroethane in rat liver microsomes is catalyzed primarily by cytochrome P-450IIE1
Drug Metab Dispos 1991 19: 298-303. [Abstract] [PDF]  

M el Mouelhi and KW Bock

Stereoselective (S)- and (R)-naproxen glucuronosyl transferases of rat liver
Drug Metab Dispos 1991 19: 304-308. [Abstract] [PDF]  

DA Joyce, RO Day, and BR Murphy

The pharmacokinetics of albumin conjugates of D-penicillamine in humans
Drug Metab Dispos 1991 19: 309-311. [Abstract] [PDF]  

MR Muirhead and AA Somogyi

Effect of H2 antagonists on the differential secretion of triamterene and its sulfate conjugate metabolite by the isolated perfused rat kidney
Drug Metab Dispos 1991 19: 312-316. [Abstract] [PDF]  

JC Kraft, W Jr Slikker, JR Bailey, LG Roberts, B Fischer, W Wittfoht, and H Nau

Plasma pharmacokinetics and metabolism of 13-cis- and all-trans- retinoic acid in the cynomolgus monkey and the identification of 13-cis- and all-trans-retinoyl-beta-glucuronides. A comparison to one human case study with isotretinoin [published erratum appears in Drug Metab Dispos Biol Fate Chem 1991 Jul-Aug;19(4):846]
Drug Metab Dispos 1991 19: 317-324. [Abstract] [PDF]  

KT Knecht and RP Mason

The detection of halocarbon-derived radical adducts in bile and liver of rats
Drug Metab Dispos 1991 19: 325-331. [Abstract] [PDF]  

TW Shih and DL Hill

Conversion of retinol to retinal by rat liver microsomes
Drug Metab Dispos 1991 19: 332-335. [Abstract] [PDF]  

TW Shih, YF Shealy, and DL Hill

Conversion of retinoid ethers to alcohols by enzymatic activity present in rat liver microsomes
Drug Metab Dispos 1991 19: 336-339. [Abstract] [PDF]  

D Goon and CD Klaassen

Intestinal biotransformation of harmol and 1-naphthol in the rat. Further evidence of dose-dependent phase-II conjugation in situ
Drug Metab Dispos 1991 19: 340-347. [Abstract] [PDF]  

CA Lee, KE Thummel, TF Kalhorn, SD Nelson, and JT Slattery

Inhibition and activation of acetaminophen reactive metabolite formation by caffeine. Roles of cytochromes P-450IA1 and IIIA2
Drug Metab Dispos 1991 19: 348-353. [Abstract] [PDF]  

L Waldhauser and J Uetrecht

Oxidation of propylthiouracil to reactive metabolites by activated neutrophils. Implications for agranulocytosis
Drug Metab Dispos 1991 19: 354-359. [Abstract] [PDF]  

J Bernadou, M Bonnafous, G Labat, P Loiseau, and B Meunier

Model systems for metabolism studies. Biomimetic oxidation of acetaminophen and ellipticine derivatives with water-soluble metalloporphyrins associated to potassium monopersulfate
Drug Metab Dispos 1991 19: 360-365. [Abstract] [PDF]  

WJ Ehlhardt and JJ Howbert

Metabolism and disposition of p-chloroaniline in rat, mouse, and monkey
Drug Metab Dispos 1991 19: 366-369. [Abstract] [PDF]  

WJ Ehlhardt

Metabolism and disposition of the anticancer agent sulofenur in mouse, rat, monkey, and human
Drug Metab Dispos 1991 19: 370-375. [Abstract] [PDF]  

O Okazaki, T Kurata, H Hakusui, and H Tachizawa

Stereoselective glucuronidation of ofloxacin in rat liver microsomes
Drug Metab Dispos 1991 19: 376-380. [Abstract] [PDF]  

AC Loh, AJ Szuna, TH Williams, GJ Sasso, and FJ Leinweber

The metabolism of [14C]rimantadine hydrochloride in rats and dogs
Drug Metab Dispos 1991 19: 381-387. [Abstract] [PDF]  

N Kurata, HE Hurst, FW Benz, RA Kemper, and WJ Waddell

Studies on inhibition and induction of metabolism of ethyl carbamate by acetone and related compounds. Evidence for metabolism by cytochromes P- 450
Drug Metab Dispos 1991 19: 388-393. [Abstract] [PDF]  

RF Mayol, HK Jajoo, LJ Klunk, and IA Blair

Metabolism of the antipsychotic drug tiospirone in humans
Drug Metab Dispos 1991 19: 394-399. [Abstract] [PDF]  

S Knapp, ML Wardlow, K Albert, D Waters, and LJ Thal

Correlation between plasma physostigmine concentrations and percentage of acetylcholinesterase inhibition over time after controlled release of physostigmine in volunteer subjects
Drug Metab Dispos 1991 19: 400-404. [Abstract] [PDF]  

SM Sanins, WJ Adams, DG Kaiser, GW Halstead, J Hosley, H Barnes, and TA Baillie

Mechanistic studies on the metabolic chiral inversion of R-ibuprofen in the rat
Drug Metab Dispos 1991 19: 405-410. [Abstract] [PDF]  

NA Mahmood, D Overstreet, and LT Burka

Comparative disposition and metabolism of 1,2,3-trichloropropane in rats and mice
Drug Metab Dispos 1991 19: 411-418. [Abstract] [PDF]  

T Sakai, H Yoshida, A Fukui, and M Takaori

Urinary and biliary excretion of metabolites of halothane in dogs
Drug Metab Dispos 1991 19: 419-422. [Abstract] [PDF]  

SD Studenberg and KL Brouwer

Phenacetin and acetaminophen metabolism in the isolated perfused rat liver. Precursor concentration influences the selection of kinetic parameters to assess hypoxic impairment
Drug Metab Dispos 1991 19: 423-429. [Abstract] [PDF]  

A Bortolotti, M Corada, MM Barzago, A Celardo, A Guaitani, and M Bonati

Pharmacokinetics of theophylline in the newborn and adult rabbit. In vivo and isolated perfused liver approaches
Drug Metab Dispos 1991 19: 430-435. [Abstract] [PDF]  

DW Herr, JM Sanders, and HB Matthews

Brain distribution and fate of tris(2-chloroethyl) phosphate in Fischer 344 rats
Drug Metab Dispos 1991 19: 436-442. [Abstract] [PDF]  

LT Burka, JM Sanders, DW Herr, and HB Matthews

Metabolism of tris(2-chloroethyl) phosphate in rats and mice
Drug Metab Dispos 1991 19: 443-447. [Abstract] [PDF]  

T Walle and UK Walle

Stereoselective sulfate conjugation of racemic 4-hydroxypropranolol by human and rat liver cytosol
Drug Metab Dispos 1991 19: 448-453. [Abstract] [PDF]  

G Grosa, O Caputo, M Ceruti, G Biglino, JS Franzone, and C Cravanzola

Metabolism of 7-(1,3-dithiolan-2-ylmethyl)-1,3-dimethylxanthine by rat liver microsomes. Diastereoselective metabolism of the 1,3-dithiolane ring
Drug Metab Dispos 1991 19: 454-457. [Abstract] [PDF]  

O Grech-Belanger, J Turgeon, M Lalande, and PM Belanger

Meta-hydroxymexiletine, a new metabolite of mexiletine. Isolation, characterization, and species differences in its formation
Drug Metab Dispos 1991 19: 458-461. [Abstract] [PDF]  

RL Yeager, KR Brouwer, and GT Miwa

(-)-6-Aminocarbovir pharmacokinetics and relative carbovir exposure in rats
Drug Metab Dispos 1991 19: 462-466. [Abstract] [PDF]  

JL Bolton and JA Thompson

Oxidation of butylated hydroxytoluene to toxic metabolites. Factors influencing hydroxylation and quinone methide formation by hepatic and pulmonary microsomes
Drug Metab Dispos 1991 19: 467-472. [Abstract] [PDF]  

HX Zhang and LG Sultatos

Biotransformation of the organophosphorus insecticides parathion and methyl parathion in male and female rat livers perfused in situ
Drug Metab Dispos 1991 19: 473-477. [Abstract] [PDF]  

SP Khor and M Mayersohn

Potential error in the measurement of tissue to blood distribution coefficients in physiological pharmacokinetic modeling. Residual tissue blood. I. Theoretical considerations
Drug Metab Dispos 1991 19: 478-485. [Abstract] [PDF]  

SP Khor, H Bozigian, and M Mayersohn

Potential error in the measurement of tissue to blood distribution coefficients in physiological pharmacokinetic modeling. Residual tissue blood. II. Distribution of phencyclidine in the rat
Drug Metab Dispos 1991 19: 486-490. [Abstract] [PDF]  

DK Patel, JL Jr Woolley, JP Shcokcor, RL Johnson, LC Taylor, and CW Sigel

Disposition, metabolism, and excretion of the anticancer agent crisnatol in the rat
Drug Metab Dispos 1991 19: 491-497. [Abstract] [PDF]  

BW Manning, MR Franklin, and RE Galinsky

Drug metabolizing enzyme changes after chronic buthionine sulfoximine exposure modify acetaminophen disposition in rats
Drug Metab Dispos 1991 19: 498-502. [Abstract] [PDF]  

AJ Kilbane, T Petroff, and WW Weber

Kinetics of acetyl CoA: arylamine N-acetyltransferase from rapid and slow acetylator human liver
Drug Metab Dispos 1991 19: 503-507. [Abstract] [PDF]  

JW Tracy, BA Catto, and LT Jr Webster

Formation of N-(5-nitro-2-thiazolyl)-N'-carboxymethylurea from 5- hydroxyniridazole. Role of aldehyde dehydrogenase in the oxidative metabolism of niridazole
Drug Metab Dispos 1991 19: 508-515. [Abstract] [PDF]  

MW Lame, AD Jones, D Morin, and HJ Segall

Metabolism of [14C]monocrotaline by isolated perfused rat liver
Drug Metab Dispos 1991 19: 516-524. [Abstract] [PDF]  

K Kassahun, K Farrell, and F Abbott

Identification and characterization of the glutathione and N- acetylcysteine conjugates of (E)-2-propyl-2,4-pentadienoic acid, a toxic metabolite of valproic acid, in rats and humans
Drug Metab Dispos 1991 19: 525-535. [Abstract] [PDF]  

MO James, JD Schell, MG Barron, and CL Li

Rapid, dose-dependent elimination of phenol across the gills, and slow elimination of phenyl sulfate in the urine of phenol-dosed lobsters, Homarus americanus
Drug Metab Dispos 1991 19: 536-542. [Abstract] [PDF]  

SI Rao and MW Duffel

Inhibition of aryl sulfotransferase by carboxylic acids
Drug Metab Dispos 1991 19: 543-545. [Abstract] [PDF]  

F Chanoine, C Grenot, P Heidmann, and JL Junien

Pharmacokinetics of butixocort 21-propionate, budesonide, and beclomethasone dipropionate in the rat after intratracheal, intravenous, and oral treatments
Drug Metab Dispos 1991 19: 546-553. [Abstract] [PDF]  

H Takahashi, H Ogata, and Y Seki

Binding interaction between enantiomers of disopyramide and mono-N- dealkyldisopyramide on plasma protein
Drug Metab Dispos 1991 19: 554-557. [PDF]  

JT Slattery, TF Kalhorn, and KE Thummel

Mechanisms by which acetaminophen administration diminishes ethanol clearance
Drug Metab Dispos 1991 19: 558-560. [PDF]  

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