Reviews:

DM Ziegler

The 1990 Bernard B. Brodie Award Lecture. Unique properties of the enzymes of detoxication
Drug Metab Dispos 1991 19: 847-852. [PDF]  

Articles:

S Iwakawa, H Spahn, LZ Benet, and ET Lin

Stereoselective disposition of carprofen, flunoxaprofen, and naproxen in rats
Drug Metab Dispos 1991 19: 853-857. [Abstract] [PDF]  

RL Chan, SC Hsieh, PE Haroldsen, W Ho, and JJ Jr Nestor

Disposition of RS-26306, a potent luteinizing hormone-releasing hormone antagonist, in monkeys and rats after single intravenous and subcutaneous administration
Drug Metab Dispos 1991 19: 858-864. [Abstract] [PDF]  

OS Sohn, L Blackwell, J Mathis, WW Asaad, BS Reddy, and K el-Bayoumy

Excretion and tissue distribution of selenium following treatment of male F344 rats with benzylselenocyanate or sodium selenite
Drug Metab Dispos 1991 19: 865-870. [Abstract] [PDF]  

J Blanz, K Mewes, G Ehninger, B Proksch, D Waidelich, B Greger, and KP Zeller

Evidence for oxidative activation of mitoxantrone in human, pig, and rat
Drug Metab Dispos 1991 19: 871-880. [Abstract] [PDF]  

SW Frantz, CM Grosse, MJ Tallant, and B Ballantyne

Pharmacokinetics of 2-ethyl-1,3-hexanediol. I. Systemic disposition following single intravenous doses in male Fischer 344 rats
Drug Metab Dispos 1991 19: 881-888. [Abstract] [PDF]  

UG Eriksson, J Lundahl, C Baarnhielm, and CG Regardh

Stereoselective metabolism of felodipine in liver microsomes from rat, dog, and human
Drug Metab Dispos 1991 19: 889-894. [Abstract] [PDF]  

T Ishida, M Yano, and S Toki

In vivo formation of codeinone and morphinone from codeine. Isolation and identification from guinea pig bile
Drug Metab Dispos 1991 19: 895-899. [Abstract] [PDF]  

AE Cribb, M Miller, JS Leeder, J Hill, and SP Spielberg

Reactions of the nitroso and hydroxylamine metabolites of sulfamethoxazole with reduced glutathione. Implications for idiosyncratic toxicity
Drug Metab Dispos 1991 19: 900-906. [Abstract] [PDF]  

BL Hoesterey, RE Galinsky, and BD Anderson

Dose dependence in the plasma pharmacokinetics and uptake kinetics of 2',3'-dideoxyinosine into brain and cerebrospinal fluid of rats
Drug Metab Dispos 1991 19: 907-912. [Abstract] [PDF]  

E Benfenati, R Fanelli, E Bosone, C Biffi, R Caponi, M Cianetti, and P Farina

Mass spectrometric identification of urinary and plasma metabolites of 6-(6'-carboxyhexyl)-7-n-hexyl-1,3-diazaspiro-[4-4]-nonan-2,4-dione, a new cytoprotective agent
Drug Metab Dispos 1991 19: 913-916. [Abstract] [PDF]  

LS Zhang, T Yoshida, K Aoki, and Y Kuroiwa

Metabolism of cinobufagin in rat liver microsomes. Identification of epimerized and deacetylated metabolites by liquid chromatography/mass spectrometry
Drug Metab Dispos 1991 19: 917-919. [Abstract] [PDF]  

W Kuhnz, GA Hoyer, S Backhus, and U Jakobs

Identification of the major metabolites of the prostaglandin E2- analogue sulprostone in human plasma, and isolation from urine (in vivo) and liver perfusate (in vitro) of female guinea-pigs
Drug Metab Dispos 1991 19: 920-925. [Abstract] [PDF]  

JH Lin, DE Duggan, IW Chen, and RL Ellsworth

Physiological disposition of alendronate, a potent anti-osteolytic bisphosphonate, in laboratory animals
Drug Metab Dispos 1991 19: 926-932. [Abstract] [PDF]  

DW Hein, TD Rustan, KD Bucher, WJ Martin, and EJ Furman

Acetylator phenotype-dependent and -independent expression of arylamine N-acetyltransferase isozymes in rapid and slow acetylator inbred rat liver
Drug Metab Dispos 1991 19: 933-937. [Abstract] [PDF]  

DM Edwards, P Marrari, C Efthymiopoulos, G Basileo, D Fraier, E Pianezzola, and M Strolin-Benedetti

Pharmacokinetics of iododoxorubicin in the rat, dog, and monkey
Drug Metab Dispos 1991 19: 938-945. [Abstract] [PDF]  

M Seaton, GA Kyerematen, M Morgan, EV Jeszenka, and ES Vesell

Nicotine metabolism in stumptailed macaques, Macaca arctoides
Drug Metab Dispos 1991 19: 946-954. [Abstract] [PDF]  

T Ebner, CO Meese, P Fischer, and M Eichelbaum

A nuclear magnetic resonance study of sparteine delta metabolite structure
Drug Metab Dispos 1991 19: 955-959. [Abstract] [PDF]  

M Yoshikawa, S Nishiyama, H Endo, Y Togo, and O Takaiti

First pass metabolism and in vitro metabolism of a new orally active dopamine prodrug, N-(N-acetyl-L-methionyl)-O,O- bis(ethoxycarbonyl)dopamine in dogs
Drug Metab Dispos 1991 19: 960-965. [Abstract] [PDF]  

CA Lee, KE Thummel, TF Kalhorn, SD Nelson, and JT Slattery

Activation of acetaminophen-reactive metabolite formation by methylxanthines and known cytochrome P-450 activators
Drug Metab Dispos 1991 19: 966-971. [Abstract] [PDF]  

S Kobayashi, K Takai, T Iga, and M Hanano

Pharmacokinetic analysis of the disposition of valproate in pregnant rats
Drug Metab Dispos 1991 19: 972-976. [Abstract] [PDF]  

W Ruangyuttikarn, ML Appleton, and GS Yost

Metabolism of 3-methylindole in human tissues
Drug Metab Dispos 1991 19: 977-984. [Abstract] [PDF]  

C Lambert, JR Halpert, J Rouleau, L Jutras, V Leroyer, and P du Souich

Effect of congestive heart failure on the intrinsic metabolic capacity of the liver in the dog
Drug Metab Dispos 1991 19: 985-989. [Abstract] [PDF]  

K Singh, SL Tripp, AW Dunton, FL Douglas, and A Rakhit

Determination of in vivo hepatic extraction ratio from in vitro metabolism by rat hepatocytes
Drug Metab Dispos 1991 19: 990-996. [Abstract] [PDF]  

D Thomassen, PG Pearson, JT Slattery, and SD Nelson

Partial characterization of biliary metabolites of pulegone by tandem mass spectrometry. Detection of glucuronide, glutathione, and glutathionyl glucuronide conjugates
Drug Metab Dispos 1991 19: 997-1003. [Abstract] [PDF]  

MJ Olson, JT Johnson, JF O'Gara, and SE Jr Surbrook

Metabolism in vivo and in vitro of the refrigerant substitute 1,1,1,2- tetrafluoro-2-chloroethane
Drug Metab Dispos 1991 19: 1004-1011. [Abstract] [PDF]  

SE Mongrain and WH Soine

Product enantioselectivity in the N-glucosylation of amobarbital by cats
Drug Metab Dispos 1991 19: 1012-1013. [PDF]  

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