Reviews:

DE Moody, GG Gibson, DF Grant, J Magdalou, and MS Rao

Peroxisome proliferators, a unique set of drug-metabolizing enzyme inducers: commentary on a symposium
Drug Metab Dispos 1992 20: 779-791. [PDF]  

Articles:

X Ding, HM Peng, SJ Pernecky, CJ Davis, and MJ Coon

Induction of P-450 cytochromes 2E2, 1A1, and 1A2 by imidazole in neonatal rabbits
Drug Metab Dispos 1992 20: 792-796. [Abstract] [PDF]  

L Corcos

Phenobarbital and dexamethasone induce expression of cytochrome P-450 genes from subfamilies IIB, IIC, and IIIA in mouse liver
Drug Metab Dispos 1992 20: 797-801. [Abstract] [PDF]  

AE Vickers, V Fischer, S Connors, RL Fisher, JP Baldeck, G Maurer, and K Brendel

Cyclosporin A metabolism in human liver, kidney, and intestine slices. Comparison to rat and dog slices and human cell lines
Drug Metab Dispos 1992 20: 802-809. [Abstract] [PDF]  

MJ Liu, KL Brouwer, and GM Pollack

Pharmacokinetics and pharmacodynamics of valproate analogs in rats. III. Pharmacokinetics of valproic acid, cyclohexanecarboxylic acid, and 1-methyl-1-cyclohexanecarboxylic acid in the bile-exteriorized rat
Drug Metab Dispos 1992 20: 810-815. [Abstract] [PDF]  

K Tajima, M Hashizaki, K Yamamoto, and T Mizutani

Metabolism of 3-tert-butyl-4-hydroxyanisole by horseradish peroxidase and hydrogen peroxide
Drug Metab Dispos 1992 20: 816-820. [Abstract] [PDF]  

SK Gupta, GR Granneman, RS Boger, NK Hollenberg, and RR Luther

Simultaneous modeling of the pharmacokinetic and pharmacodynamic properties of enalkiren (Abbott-64662, a new renin inhibitor). I: Single dose study
Drug Metab Dispos 1992 20: 821-825. [Abstract] [PDF]  

M Corada, A Bortolotti, MM Barzago, A Celardo, M Bonati, and A Guaitani

Pharmacokinetic profile of theophylline in isolated perfused liver of rabbits at different ages. Development of drug-metabolizing activity during ontogenesis
Drug Metab Dispos 1992 20: 826-831. [Abstract] [PDF]  

AJ Sadeque, AC Eddy, GP Meier, and AE Rettie

Stereoselective sulfoxidation by human flavin-containing monooxygenase. Evidence for catalytic diversity between hepatic, renal, and fetal forms
Drug Metab Dispos 1992 20: 832-839. [Abstract] [PDF]  

AE Mutlib, YC Chui, LM Young, and FS Abbott

Characterization of metabolites of xylazine produced in vivo and in vitro by LC/MS/MS and by GC/MS
Drug Metab Dispos 1992 20: 840-848. [Abstract] [PDF]  

LA Shipley, TJ Brown, JD Cornpropst, M Hamilton, WD Daniels, and HW Culp

Metabolism and disposition of gemcitabine, and oncolytic deoxycytidine analog, in mice, rats, and dogs
Drug Metab Dispos 1992 20: 849-855. [Abstract] [PDF]  

CE Cook, AR Jeffcoat, BM Sadler, JM Hill, RD Voyksner, DE Pugh, WR White, and M Perez-Reyes

Pharmacokinetics of oral methamphetamine and effects of repeated daily dosing in humans
Drug Metab Dispos 1992 20: 856-862. [Abstract] [PDF]  

CS Boyer and DR Petersen

Pharmacokinetic analysis of the metabolism of cocaine to norcocaine and N-hydroxynorcocaine in mice
Drug Metab Dispos 1992 20: 863-868. [Abstract] [PDF]  

SK Balani, SM Pitzenberger, LR Kauffman, BH Arison, HG Ramjit, ME Goldman, JA O'Brien, JD King, JM Hoffman, and CS Rooney

Metabolism of a new HIV-1 reverse transcriptase inhibitor, 3-[2- (benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one (L-696,229), in rat and liver slices
Drug Metab Dispos 1992 20: 869-876. [Abstract] [PDF]  

E Benoit, T Cresteil, JL Riviere, and P Delatour

Specific and enantioselective sulfoxidation of an aryl-trifluoromethyl sulfide by rat liver cytochromes P-450
Drug Metab Dispos 1992 20: 877-881. [Abstract] [PDF]  

M Hezari and PJ Davis

Microbial models of mammalian metabolism. N-dealkylation of furosemide to yield the mammalian metabolite CSA using Cunninghamella elegans
Drug Metab Dispos 1992 20: 882-888. [Abstract] [PDF]  

C Beedham, Y al-Tayib, and JA Smith

Role of guinea pig and rabbit hepatic aldehyde oxidase in oxidative in vitro metabolism of cinchona antimalarials
Drug Metab Dispos 1992 20: 889-895. [Abstract] [PDF]  

PB Styczynski, MD Green, B Coffman, and TR Tephly

Studies on tertiary amine UDP-glucuronosyltransferases from human and rabbit hepatic microsomes
Drug Metab Dispos 1992 20: 896-901. [Abstract] [PDF]  

S Zbaida, CF Brewer, and WG Levine

Substrates for microsomal azoreductase. Hammett substituent effects, NMR studies, and response to inhibitors
Drug Metab Dispos 1992 20: 902-908. [Abstract] [PDF]  

DR Krishna and D Venkataramana

Pharmacokinetics of D(+)-usnic acid in rabbits after intravenous and oral administration
Drug Metab Dispos 1992 20: 909-911. [Abstract] [PDF]  

JE Patanella and JS Walsh

Oxidation of carbovir, a carbocyclic nucleoside, by rat liver cytosolic enzymes. Enantioselectivity and enantiomeric inhibition
Drug Metab Dispos 1992 20: 912-919. [Abstract] [PDF]  

DL Deal, P Chandrasurin, J Shockcor, DJ Minick, JW Findlay, and MJ McNulty

Disposition and metabolism of triprolidine in mice
Drug Metab Dispos 1992 20: 920-927. [Abstract] [PDF]  

MJ McNulty, DL Deal, TL Page, P Chandrasurin, and JW Findlay

Disposition of triprolidine in the male beagle dog
Drug Metab Dispos 1992 20: 928-935. [Abstract] [PDF]  

DH Ho, WP Covington, R Pazdur, NS Brown, J Kuritani, RA Newman, MN Raber, and IH Krakoff

Clinical pharmacology of combined oral uracil and ftorafur
Drug Metab Dispos 1992 20: 936-940. [Abstract] [PDF]  

GK Poon, YC Chui, M Jarman, MG Rowlands, PS Kokkonen, WM Niessen, and J van der Greef

Investigation of conjugated metabolites of 4-hydroxyandrost-4-ene-3,17- dione in patient urine by liquid chromatography-atmospheric pressure ionization mass spectrometry
Drug Metab Dispos 1992 20: 941-947. [Abstract] [PDF]  

AD Kiss, K Haggard, JC Veltman, and DM Ziegler

Oxidation of aldose reductase inhibitors ALO-4114 and ALO-3152 catalyzed by liver microsomes
Drug Metab Dispos 1992 20: 948-953. [Abstract] [PDF]  

C Town, D Chang, L Henderson, and WA Garland

Disposition of the human immunodeficiency virus Tat inhibitor, Ro 5- 3335, in rats and dogs
Drug Metab Dispos 1992 20: 954-957. [PDF]  

WJ Ehlhardt, JL Zimmermann, JE Ray, and JE Toth

Formation of indenesulfonylureas in the metabolism of the anticancer agent sulofenur in rats, monkeys, and humans
Drug Metab Dispos 1992 20: 958-961. [PDF]  

PC Smith, WQ Song, and RJ Rodriguez

Covalent binding of etodolac acyl glucuronide to albumin in vitro
Drug Metab Dispos 1992 20: 962-965. [PDF]  

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