Articles:

W Krause, B Dusterberg, U Jakobs, and GA Hoyer

Biotransformation of proterguride in the perfused rat liver
Drug Metab Dispos 1993 21: 203-208. [Abstract] [PDF]  

AA Nomeir, PM Markham, BI Ghanayem, and M Chadwick

Disposition of the flame retardant 1,2-bis(2,4,6-tribromophenoxy)ethane in rats following administration in the diet
Drug Metab Dispos 1993 21: 209-214. [Abstract] [PDF]  

MC Garcia-Carbonell, L Granero, F Torres-Molina, JC Aristorena, J Chesa- Jimenez, JM Pla-Delfina, and JE Peris-Ribera

Nonlinear pharmacokinetics of cefadroxil in the rat
Drug Metab Dispos 1993 21: 215-217. [Abstract] [PDF]  

MG Boersma, NH Cnubben, WJ van Berkel, M Blom, J Vervoort, and IM Rietjens

Role of cytochromes P-450 and flavin-containing monooxygenase in the biotransformation of 4-fluoro-N-methylaniline
Drug Metab Dispos 1993 21: 218-230. [Abstract] [PDF]  

SM el Dareer, KF Tillery, LM Rose, CF Posey, RF Struck, SW Stiller, and DL Hill

Metabolism and disposition of a thiazolobenzimidazole active against human immunodeficiency virus-1
Drug Metab Dispos 1993 21: 231-235. [Abstract] [PDF]  

U Martin, G Sponer, and K Strein

Influence of hepatic and renal failure on pharmacokinetic properties of the novel recombinant plasminogen activator BM 06.022 in rats
Drug Metab Dispos 1993 21: 236-241. [Abstract] [PDF]  

K Kassahun and TA Baillie

Cytochrome P-450-mediated dehydrogenation of 2-n-propyl-2(E)-pentenoic acid, a pharmacologically-active metabolite of valproic acid, in rat liver microsomal preparations
Drug Metab Dispos 1993 21: 242-248. [Abstract] [PDF]  

PM Franz, EL Mattiuz, BL Hatcher, KA DeSante, AP Breau, JL Occolowitz, DE Dorman, CR Schmid, MJ Goldberg, and A Rubin

Disposition of zatosetron, a serotonin (5-HT3) receptor antagonist, in humans
Drug Metab Dispos 1993 21: 249-254. [Abstract] [PDF]  

AM Fredenburg, PJ Wedlund, TL Skinner, LA Damani, RC Hider, and RA Yokel

Pharmacokinetics of representative 3-hydroxypyridin-4-ones in rabbits: CP20 and CP94
Drug Metab Dispos 1993 21: 255-258. [Abstract] [PDF]  

M Hezari and PJ Davis

Microbial models of mammalian metabolism. Furosemide glucoside formation using the fungus Cunninghamella elegans
Drug Metab Dispos 1993 21: 259-267. [Abstract] [PDF]  

IA Aksoy, DM Otterness, and RM Weinshilboum

Cholesterol sulfation in human liver. Catalysis by dehydroepiandrosterone sulfotransferase
Drug Metab Dispos 1993 21: 268-276. [Abstract] [PDF]  

DE Smith, DE Brenner, CA Knutsen, SJ Deremer, PA Terrio, NJ Johnson, PL Stetson, and WD Ensminger

Mutual kinetic interaction between 5-fluorouracil and bromodeoxyuridine or iododeoxyuridine in dogs
Drug Metab Dispos 1993 21: 277-283. [Abstract] [PDF]  

K Yeleswaram, DW Rurak, E Kwan, C Hall, A Doroudian, FS Abbott, and JE Axelson

Disposition, metabolism, and pharmacodynamics of labetalol in adult sheep
Drug Metab Dispos 1993 21: 284-292. [Abstract] [PDF]  

L Bouchard and A Castonguay

Inhibitory effects of nonsteroidal anti-inflammatory drugs (NSAIDs) on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in mouse lung explants [published erratum appears in Drug Metab Dispos Biol Fate Chem 1993 Sep-Oct;21(5):970]
Drug Metab Dispos 1993 21: 293-298. [Abstract] [PDF]  

Y Wang and MT Baker

NADPH and oxygen consumption in isoflurane-facilitated 2-chloro-1,1- difluoroethene metabolism in rabbit liver microsomes
Drug Metab Dispos 1993 21: 299-304. [Abstract] [PDF]  

KM Walters, WD Mason, and MZ Badr

Effect of propylene glycol on the disposition of Dramamine in the rabbit
Drug Metab Dispos 1993 21: 305-308. [Abstract] [PDF]  

M Kim, DD Shen, AC Eddy, WL Nelson, and LK Roskos

Inhibition of the enantioselective oxidative metabolism of metoprolol by verapamil in human liver microsomes [published erratum appears in Drug Metab Dispos Biol Fate Chem 1993 Sep-Oct;21(5):970]
Drug Metab Dispos 1993 21: 309-317. [Abstract] [PDF]  

R Jorquera, A Castonguay, and HM Schuller

Effect of tobacco smoke condensate on the metabolism of 4- (methylnitrosamino)-1-(3-pyridyl)-1-butanone by adult and fetal hamster microsomes
Drug Metab Dispos 1993 21: 318-324. [Abstract]  

T Wikberg and J Taskinen

Identification of major metabolites of the catechol-O-methyltransferase inhibitor nitecapone in the rat and dog
Drug Metab Dispos 1993 21: 325-333. [Abstract] [PDF]  

KC Falkner, GP McCallum, and JR Bend

Effects of arsenite treatment on NAD(P)H:quinone acceptor oxidoreductase activity in liver, lung, kidney, and heart of the rat. Comparison to induction by the polyaromatic hydrocarbon, beta- naphthoflavone
Drug Metab Dispos 1993 21: 334-337. [Abstract] [PDF]  

B Lacarelle, JF Rajaonarison, J Catalin, A Durand, and JP Cano

UDP-glucuronosyltransferase activity toward digitoxigenin monodigitoxoside in human liver microsomes
Drug Metab Dispos 1993 21: 338-341. [Abstract] [PDF]  

C Madhu, DY Mitchell, and CD Klaassen

Effect of P-450 inducers on biliary excretion of glutathione and its hydrolysis products. Correlation between hepatic gamma- glutamyltranspeptidase activity and the proportion of glutathione hydrolysis products in bile
Drug Metab Dispos 1993 21: 342-349. [Abstract] [PDF]  

KE Thummel, ED Kharasch, T Podoll, and K Kunze

Human liver microsomal enflurane defluorination catalyzed by cytochrome P-450 2E1
Drug Metab Dispos 1993 21: 350-357. [Abstract] [PDF]  

S Ohmori, I Ishii, S Kuriya, T Taniguchi, T Rikihisa, S Hirose, Y Kanakubo, and M Kitada

Effects of clarithromycin and its metabolites on the mixed function oxidase system in hepatic microsomes of rats
Drug Metab Dispos 1993 21: 358-363. [Abstract] [PDF]  

Z Binienda, JR Bailey, HM Duhart, W Jr Slikker, and MG Paule

Transplacental pharmacokinetics and maternal/fetal plasma concentrations of cocaine in pregnant macaques near term
Drug Metab Dispos 1993 21: 364-368. [Abstract] [PDF]  

G Ahluwalia, DA Cooney, NR Hartman, H Mitsuya, R Yarchoan, A Fridland, S Broder, and DG Johns

Anomalous accumulation and decay of 2',3'-dideoxyadenosine-5'- triphosphate in human T-cell cultures exposed to the anti-HIV drug 2',3'-dideoxyinosine
Drug Metab Dispos 1993 21: 369-376. [Abstract] [PDF]  

JP Cravedi, G Delous, L Debrauwer, and D Prome

Biotransformation and branchial excretion of 17 alpha- methyltestosterone in trout
Drug Metab Dispos 1993 21: 377-385. [Abstract] [PDF]  

RC Lind and AJ Gandolfi

Concentration-dependent inhibition of halothane biotransformation in the guinea pig
Drug Metab Dispos 1993 21: 386-389. [Abstract] [PDF]  

JA Sandberg, LJ Murphey, and GD Olsen

In vitro hepatic biotransformation of cocaine in maternal and fetal guinea pigs. Induction of cocaine N-demethylation with cocaine pretreatment
Drug Metab Dispos 1993 21: 390-395. [Abstract] [PDF]  

DY Mitchell and DR Petersen

Inhibition of rat liver mitochondrial and cytosolic aldehyde dehydrogenases by crotonaldehyde
Drug Metab Dispos 1993 21: 396-399. [PDF]  

MW Duffel and Y Zheng

Naphthaldehydes as reversible inhibitors of rat hepatic aryl sulfotransferase IV (tyrosine-ester sulfotransferase)
Drug Metab Dispos 1993 21: 400-402. [PDF]  

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