Articles:

CH Yun, RA Okerholm, and FP Guengerich

Oxidation of the antihistaminic drug terfenadine in human liver microsomes. Role of cytochrome P-450 3A(4) in N-dealkylation and C- hydroxylation
Drug Metab Dispos 1993 21: 403-409. [Abstract] [PDF]  

JF Muindi, YW Stevens, RP Jr Warrell, and CW Young

In vitro differential metabolism of merbarone by xanthine oxidase and microsomal flavoenzymes. The role of reactive oxygen species
Drug Metab Dispos 1993 21: 410-414. [Abstract] [PDF]  

AG Borel and FS Abbott

Metabolic profiling of clobazam, a 1,5-benzodiazepine, in rats
Drug Metab Dispos 1993 21: 415-427. [Abstract] [PDF]  

RD Bongard, DL Roerig, MR Johnston, JH Linehan, and CA Dawson

Influence of temperature and plasma protein on doxorubicin uptake by isolated lungs
Drug Metab Dispos 1993 21: 428-434. [Abstract] [PDF]  

H Lennernas, L Renberg, KJ Hoffmann, and CG Regardh

Presystemic elimination of the beta-blocker pafenolol in the rat after oral and intraperitoneal administration and identification of a main metabolite in both rats and humans
Drug Metab Dispos 1993 21: 435-440. [Abstract] [PDF]  

RF Witkamp, SM Nijmeijer, H Yun, J Noordhoek, and AS van Miert

Sulfamethazine as a model compound to assess sex hormone-dependent cytochrome P-450 activity in rats
Drug Metab Dispos 1993 21: 441-446. [Abstract] [PDF]  

S Kaul, WC Shyu, UA Shukla, KA Dandekar, and RH Barbhaiya

Absorption, disposition, and metabolism of [14C]didanosine in the beagle dog
Drug Metab Dispos 1993 21: 447-453. [Abstract] [PDF]  

AE Vickers, S Connors, M Zollinger, WA Biggi, A Larrauri, JP Vogelaar, and K Brendel

The biotransformation of the ergot derivative CQA 206-291 in human, dog, and rat liver slice cultures and prediction of in vivo plasma clearance
Drug Metab Dispos 1993 21: 454-459. [Abstract] [PDF]  

MY Farooqui, B Ybarra, and J Piper

Toxicokinetics of allynitrile in rats
Drug Metab Dispos 1993 21: 460-466. [Abstract] [PDF]  

S Vickers, CA Duncan, PH Kari, CF Homnick, JM Elliott, SM Pitzenberger, M Hichens, and KP Vyas

In vivo and in vitro metabolism studies on a class III antiarrhythmic agent
Drug Metab Dispos 1993 21: 467-473. [Abstract] [PDF]  

TS Piatkowski, WW Day, and M Weiner

Increased renal drug metabolism in treadmill-exercised Fischer-344 male rats
Drug Metab Dispos 1993 21: 474-479. [Abstract] [PDF]  

SL Durham, JF Hoke, and TM Chen

Pharmacokinetics and metabolism of vigabatrin following a single oral dose of [14C]vigabatrin in healthy male volunteers
Drug Metab Dispos 1993 21: 480-484. [Abstract] [PDF]  

S Perreault, L Dumont, V Villiere, H Ong, A Adam, and P du Souich

Hepatic and extrahepatic metabolism of salbutamol in anesthetized rabbits
Drug Metab Dispos 1993 21: 485-491. [Abstract] [PDF]  

JR Cashman, Z Yang, L Yang, and SA Wrighton

Stereo- and regioselective N- and S-oxidation of tertiary amines and sulfides in the presence of adult human liver microsomes [published erratum appears in Drug Metab Dispos Biol Fate Chem 1993 Nov- Dec;21(6):1174]
Drug Metab Dispos 1993 21: 492-501. [Abstract] [PDF]  

UA Shukla, PH Marathe, KA Pittman, and RH Barbhaiya

Pharmacokinetics, absolute bioavailability, and disposition of [14C]nefazodone in the dog
Drug Metab Dispos 1993 21: 502-507. [Abstract] [PDF]  

B Tyrakowska, S Boeren, B Geurtsen, and IM Rietjens

Qualitative and quantitative influences of ortho chlorine substituents on the microsomal metabolism of 4-toluidines
Drug Metab Dispos 1993 21: 508-519. [Abstract] [PDF]  

E Delaporte, AE Cribb, and KW Renton

Modulation of rat hepatic CYP3A1 induction by the interferon inducer polyinosinic acid-polycytidylic acid (polyic)
Drug Metab Dispos 1993 21: 520-523. [Abstract] [PDF]  

T Uchida, T Usui, T Teramura, T Watanabe, and S Higuchi

Metabolic N-demethylation of 1,3-bis[[1-cycloheptyl-3-(p- dimethylaminophenyl)ureido]methyl]benzene dihydrochloride, a novel acyl- coenzyme A:cholesterol acyltransferase inhibitor
Drug Metab Dispos 1993 21: 524-529. [Abstract] [PDF]  

IG Robertson, BD Palmer, JW Paxton, and TJ Bland

Metabolism of the experimental antitumor agent acridine carboxamide in the mouse
Drug Metab Dispos 1993 21: 530-536. [Abstract] [PDF]  

SM Roberts, RD Harbison, and RC James

Inhibition by ethanol of the metabolism of cocaine to benzoylecgonine and ecgonine methyl ester in mouse and human liver
Drug Metab Dispos 1993 21: 537-541. [Abstract] [PDF]  

M Nakano, T Chikai, and T Matsubara

Enantiomer-enantiomer interaction on N-monodemethylation of diuretic in rat liver microsomes
Drug Metab Dispos 1993 21: 542-543. [PDF]  

JT Dalton and JL Au

2',3'-Dideoxyinosine is not metabolized in human placenta
Drug Metab Dispos 1993 21: 544-546. [PDF]  

M Kukan, TF Woolf, M Melus, and S Bezek

Characterization of nonlinear elimination of the xanthine-related drug ethimizol in 3-methylcholanthrene-induced rat liver by the "parallel- tube" model
Drug Metab Dispos 1993 21: 547-550. [PDF]  

CS Godin, JM Drerup, and A Vinegar

Conditions influencing the rat liver microsomal metabolism of 2,2,- dichloro-1,1,1-trifluoroethane (HCFC-123)
Drug Metab Dispos 1993 21: 551-553. [PDF]  

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