Articles:

JC Stevens, LA Shipley, JR Cashman, M Vandenbranden, and SA Wrighton

Comparison of human and rhesus monkey in vitro phase I and phase II hepatic drug metabolism activities
Drug Metab Dispos 1993 21: 753-760. [Abstract] [PDF]  

CM Dixon, DA Saynor, PD Andrew, J Oxford, A Bradbury, and MH Tarbit

Disposition of sumatriptan in laboratory animals and humans
Drug Metab Dispos 1993 21: 761-769. [Abstract] [PDF]  

PG Forkert and M Moussa

Temporal effects of 1,1-dichloroethylene on nonprotein sulfhydryl content in murine lung and liver
Drug Metab Dispos 1993 21: 770-776. [Abstract] [PDF]  

H Nakasa, M Komiya, S Ohmori, T Rikihisa, and M Kitada

Rat liver microsomal cytochrome P-450 responsible for reductive metabolism of zonisamide
Drug Metab Dispos 1993 21: 777-781. [Abstract] [PDF]  

PN Zannikos, AM Bandyopadhyay, LW Robertson, and RA Blouin

Effect of nutritional obesity on the induction of CYP2B enzymes following phenobarbital treatment
Drug Metab Dispos 1993 21: 782-787. [Abstract] [PDF]  

CS Okereke, AM Kadry, MS Abdel-Rahman, RA Davis, and MA Friedman

Metabolism of benzophenone-3 in rats
Drug Metab Dispos 1993 21: 788-791. [Abstract] [PDF]  

SE Huskey, RR Miller, and SH Chiu

N-glucuronidation reactions. I. Tetrazole N-glucuronidation of selected angiotensin II receptor antagonists in hepatic microsomes from rats, dogs, monkeys, and humans
Drug Metab Dispos 1993 21: 792-799. [Abstract] [PDF]  

JH Lin, IW Chen, and FA Deluna

Uptake of alendronate by bone tissue in hypocalcemic and hypercalcemic rats
Drug Metab Dispos 1993 21: 800-804. [Abstract] [PDF]  

Z Hussein, DJ Mulford, BA Bopp, and GR Granneman

Differences in the stereoselective pharmacokinetics of pazinaclone (DN- 2327), a new anxiolytic, and its active metabolite after intravenous and oral single doses to dogs
Drug Metab Dispos 1993 21: 805-810. [Abstract] [PDF]  

M Vidal, M Bonnafous, S Defrance, P Loiseau, J Bernadou, and B Meunier

Model systems for oxidative drug metabolism studies. Catalytic behavior of water-soluble metalloporphyrins depends on both the intrinsic robustness of the catalyst and the nature of substrates
Drug Metab Dispos 1993 21: 811-817. [Abstract] [PDF]  

H Berger, J Sandow, N Heinrich, E Albrecht, U Kertscher, and J Oehlke

Disposition of the 3H-labeled gonadotropin-releasing hormone analog buserelin in rats
Drug Metab Dispos 1993 21: 818-822. [Abstract] [PDF]  

JF Rajaonarison, B Lacarelle, J Catalin, A Durand, and JP Cano

Effect of anticancer drugs on the glucuronidation of 3'-azido-3'- deoxythymidine in human liver microsomes
Drug Metab Dispos 1993 21: 823-829. [Abstract] [PDF]  

JP Uetrecht, NH Shear, and N Zahid

N-chlorination of sulfamethoxazole and dapsone by the myeloperoxidase system
Drug Metab Dispos 1993 21: 830-834. [Abstract] [PDF]  

M Criscuoli, A Lippi, G Mengozzi, G Sardelli, A Subissi, and A Giachetti

Pharmacokinetics and pharmacodynamics of idrapril in rats, dogs, and humans
Drug Metab Dispos 1993 21: 835-840. [Abstract] [PDF]  

AA Elfarra and IY Hwang

Targeting of 6-mercaptopurine to the kidneys. Metabolism and kidney- selectivity of S-(6-purinyl)-L-cysteine analogs in rats
Drug Metab Dispos 1993 21: 841-845. [Abstract] [PDF]  

DW Rosenberg

Pharmacokinetics of cobalt chloride and cobalt-protoporphyrin
Drug Metab Dispos 1993 21: 846-849. [Abstract] [PDF]  

G Lhoest, N Maton, and RK Verbeeck

Isolation and identification of a novel isomerized epoxide metabolite of FK-506 from erythromycin-induced rabbit liver microsomes
Drug Metab Dispos 1993 21: 850-854. [Abstract] [PDF]  

FD Boudinot, RF Schinazi, KJ Doshi, HM McClure, and CK Chu

Pharmacokinetics and metabolism of 3'-azido-2',3'-dideoxy-5- methylcytidine in rhesus monkeys
Drug Metab Dispos 1993 21: 855-860. [Abstract] [PDF]  

DA Nicoll-Griffith, N Chauret, JA Yergey, LA Trimble, L Favreau, R Zamboni, SJ Grossman, J Drey, and E Herold

Characterization of verlukast metabolites arising from an epoxide intermediate produced with hepatic microsomes from beta-naphthoflavone- treated rodents (P-4501A1)
Drug Metab Dispos 1993 21: 861-867. [Abstract] [PDF]  

H Song and F Abramson

Drug metabolism studies using "intrinsic" and "extrinsic" labels. A demonstration using 15N vs. Cl in midazolam
Drug Metab Dispos 1993 21: 868-873. [Abstract] [PDF]  

TF Woolf, WF Pool, SM Bjorge, T Chang, OP Goel, CF 2d Purchase, MC Schroeder, KL Kunze, and WF Trager

Bioactivation and irreversible binding of the cognition activator tacrine using human and rat liver microsomal preparations. Species difference
Drug Metab Dispos 1993 21: 874-882. [Abstract] [PDF]  

BB Hasinoff

Enzymatic ring-opening reactions of the chiral cardioprotective agent (+) (S)-ICRF-187 and its (-) (R)-enantiomer ICRF-186 by dihydropyrimidine amidohydrolase
Drug Metab Dispos 1993 21: 883-888. [Abstract] [PDF]  

AG Borel and FS Abbott

Identification of carbamoylated thiol conjugates as metabolites of the antineoplastic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea, in rats and humans
Drug Metab Dispos 1993 21: 889-901. [Abstract] [PDF]  

CL Zimmerman, KR Iyer, AL 2d Faudskar, and RP Remmel

Glucuronidation as a transient intermediate metabolic step in the elimination of (-)-carbovir. Identification of (-)-carbovir-5'-O- glucuronide in rat bile
Drug Metab Dispos 1993 21: 902-910. [Abstract] [PDF]  

MM Vestling, CM Murphy, DA Keller, C Fenselau, J Dedinas, DL Ladd, and MA Olsen

A strategy for characterization of polyethylene glycol-derivatized proteins. A mass spectrometric analysis of the attachment sites in polyethylene glycol-derivatized superoxide dismutase
Drug Metab Dispos 1993 21: 911-917. [Abstract] [PDF]  

RJ Griffin and LT Burka

Metabolism and elimination of oxazepam in B6C3F1 and Swiss-Webster mice
Drug Metab Dispos 1993 21: 918-926. [Abstract] [PDF]  

MJ Seaton, GA Kyerematen, and ES Vesell

Rates of excretion of cotinine, nicotine glucuronide, and 3- hydroxycotinine glucuronide in rat bile
Drug Metab Dispos 1993 21: 927-932. [Abstract] [PDF]  

CH Chou, AM Evans, G Fornasini, and M Rowland

Relationship between lipophilicity and hepatic dispersion and distribution for a homologous series of barbiturates in the isolated perfused in situ rat liver
Drug Metab Dispos 1993 21: 933-938. [Abstract] [PDF]  

Z Jayyosi, J Villoutreix, JM Ziegler, AM Batt, F De Maack, G Siest, and PE Thomas

Identification of cytochrome P-450 isozymes involved in the hydroxylation of dantrolene by rat liver microsomes
Drug Metab Dispos 1993 21: 939-945. [Abstract] [PDF]  

EM Cretton and JP Sommadossi

Reduction of 3'-azido-2',3'-dideoxynucleosides to their 3'-amino metabolite is mediated by cytochrome P-450 and NADPH-cytochrome P-450 reductase in rat liver microsomes
Drug Metab Dispos 1993 21: 946-950. [Abstract] [PDF]  

SC Laizure, LK Franklin, DG Kaiser, CL Williams, RC Stevens, PL Sanders, and M Miller

Disposition of tirilazad (U74006F), a 21-aminosteroid, in the plasma, heart, brain, and liver of the rat
Drug Metab Dispos 1993 21: 951-954. [Abstract] [PDF]  

J Blanz, U Renner, K Schmeer, G Ehninger, and KP Zeller

Detection and identification of human urinary metabolites of biantrazole (CI-941)
Drug Metab Dispos 1993 21: 955-961. [Abstract] [PDF]  

VK Piotrovskij, Z Kallay, K Krejcy, J Horecky, T Trnovec, and G Raberger

NG-nitro-L-arginine pharmacokinetics in rats after a single intravascular and oral dose: an appearance of secondary concentration time peaks
Drug Metab Dispos 1993 21: 962-964. [PDF]  

KJ Martell and WW Weber

N-acetylation polymorphism in liver and pancreas of inbred rats
Drug Metab Dispos 1993 21: 965-966. [PDF]  

EA Kowaluk, SJ Chung, and HL Fung

Nitrite ion is not an active intermediate in the vascular metabolism of organic nitrates and organic nitrites to nitric oxide
Drug Metab Dispos 1993 21: 967-969. [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.