Articles:

K Iwasaki, T Shiraga, K Nagase, Z Tozuka, K Noda, S Sakuma, T Fujitsu, K Shimatani, A Sato, and M Fujioka

Isolation, identification, and biological activities of oxidative metabolites of FK506, a potent immunosuppressive macrolide lactone
Drug Metab Dispos 1993 21: 971-977. [Abstract] [PDF]  

G Fabre, B Julian, B Saint-Aubert, H Joyeux, and Y Berger

Evidence for CYP3A-mediated N-deethylation of amiodarone in human liver microsomal fractions
Drug Metab Dispos 1993 21: 978-985. [Abstract] [PDF]  

MG Bolton, J Hilton, KD Robertson, RT Streeper, OM Colvin, and DA Noe

Kinetic analysis of the reaction of melphalan with water, phosphate, and glutathione
Drug Metab Dispos 1993 21: 986-996. [Abstract] [PDF]  

A Sabouraud, M Redureau, P Gires, M Martinet, and JM Scherrmann

Effect of colchicine-specific Fab fragments on the hepatic clearance of colchicine
Drug Metab Dispos 1993 21: 997-1002. [Abstract] [PDF]  

RA Halpin, EH Ulm, AE Till, PH Kari, KP Vyas, DB Hunninghake, and DE Duggan

Biotransformation of lovastatin. V. Species differences in in vivo metabolite profiles of mouse, rat, dog, and human
Drug Metab Dispos 1993 21: 1003-1011. [Abstract] [PDF]  

Y Masubuchi, N Kagimoto, S Narimatsu, S Fujita, and T Suzuki

Regioselective contribution of the cytochrome P-450 2D subfamily to propranolol metabolism in rat liver microsomes
Drug Metab Dispos 1993 21: 1012-1016. [Abstract] [PDF]  

I Bekersky, RJ Puhl, G Hanson, and S Mong

Disposition of a new antiinfective agent 1,3-di(4-imidazolino-2- methoxyphenoxy)propane in male rats
Drug Metab Dispos 1993 21: 1017-1021. [Abstract] [PDF]  

GR Manchee, A Barrow, S Kulkarni, E Palmer, J Oxford, PV Colthup, JG Maconochie, and MH Tarbit

Disposition of salmeterol xinafoate in laboratory animals and humans
Drug Metab Dispos 1993 21: 1022-1028. [Abstract] [PDF]  

SJ Grossman, EG Herold, JM Drey, DW Alberts, DR Umbenhauer, DH Patrick, D Nicoll-Griffith, N Chauret, and JA Yergey

CYP1A1 specificity of Verlukast epoxidation in mice, rats, rhesus monkeys, and humans
Drug Metab Dispos 1993 21: 1029-1036. [Abstract] [PDF]  

RG Turcan, D Hillbeck, TE Hartley, PJ Gilbert, RA Coe, JA Troke, and CW Vose

Disposition of [14C]velnacrine maleate in rats, dogs, and humans
Drug Metab Dispos 1993 21: 1037-1047. [Abstract] [PDF]  

M Mimura, T Baba, H Yamazaki, S Ohmori, Y Inui, FJ Gonzalez, FP Guengerich, and T Shimada

Characterization of cytochrome P-450 2B6 in human liver microsomes
Drug Metab Dispos 1993 21: 1048-1056. [Abstract] [PDF]  

JG Chung, GN Levy, and WW Weber

Distribution of 2-aminofluorene and p-aminobenzoic acid N- acetyltransferase activity in tissues of C57BL/6J rapid and B6.A-NatS slow acetylator congenic mice
Drug Metab Dispos 1993 21: 1057-1063. [Abstract] [PDF]  

SM Toler, AB Young, CJ McClain, SI Shedlofsky, AM Bandyopadhyay, and RA Blouin

Head injury and cytochrome P-450 enzymes. Differential effect on mRNA and protein expression in the Fischer-344 rat
Drug Metab Dispos 1993 21: 1064-1069. [Abstract] [PDF]  

Y Zhao, CA Snel, GJ Mulder, and KS Pang

Localization of glutathione conjugation activities toward bromosulfophthalein in perfused rat liver. Studies with the multiple indicator dilution technique
Drug Metab Dispos 1993 21: 1070-1078. [Abstract] [PDF]  

VE Adusumalli, JK Wichmann, N Kucharczyk, and RD Sofia

Distribution of the anticonvulsant felbamate to cerebrospinal fluid and brain tissue of adult and neonatal rats
Drug Metab Dispos 1993 21: 1079-1085. [Abstract] [PDF]  

LE Los, AB Coddington, HG Ramjit, and HD Colby

Identification of spironolactone metabolites in plasma and target organs of guinea pigs
Drug Metab Dispos 1993 21: 1086-1090. [Abstract] [PDF]  

W Zheng, SM Winter, M Mayersohn, JB Bishop, and IG Sipes

Toxicokinetics of sulfasalazine (salicylazosulfapyridine) and its metabolites in B6C3F1 mice
Drug Metab Dispos 1993 21: 1091-1097. [Abstract] [PDF]  

K Kassahun and F Abbott

In vivo formation of the thiol conjugates of reactive metabolites of 4- ene VPA and its analog 4-pentenoic acid
Drug Metab Dispos 1993 21: 1098-1106. [Abstract] [PDF]  

MS Bogdanffy and ML Taylor

Kinetics of nasal carboxylesterase-mediated metabolism of vinyl acetate
Drug Metab Dispos 1993 21: 1107-1111. [Abstract] [PDF]  

TF Woolf, A Black, YY Shum, W McNally, H Lee, and T Chang

Biodisposition studies with the acyl-coenzyme A: cholesterol acyltransferase inhibitor 2,2-dimethyl-N-(2,4,6- trimethoxyphenyl)dodecanamide, CI-976
Drug Metab Dispos 1993 21: 1112-1118. [Abstract] [PDF]  

GK Poon, YC Chui, R McCague, PE Llnning, R Feng, MG Rowlands, and M Jarman

Analysis of phase I and phase II metabolites of tamoxifen in breast cancer patients
Drug Metab Dispos 1993 21: 1119-1124. [Abstract] [PDF]  

C Fernandez, V Maradeix, F Gimenez, A Thuillier, and R Farinotti

Pharmacokinetics of zopiclone and its enantiomers in Caucasian young healthy volunteers
Drug Metab Dispos 1993 21: 1125-1128. [Abstract] [PDF]  

KL Brouwer

Acute phenobarbital administration alters the disposition of acetaminophen metabolites in the rat
Drug Metab Dispos 1993 21: 1129-1133. [Abstract] [PDF]  

G Mannens, ML Huang, W Meuldermans, J Hendrickx, R Woestenborghs, and J Heykants

Absorption, metabolism, and excretion of risperidone in humans
Drug Metab Dispos 1993 21: 1134-1141. [Abstract] [PDF]  

T Yoshida, T Tabuchi, and K Andoh

Pharmacokinetic study of p-chloronitrobenzene in humans suffering from acute poisoning
Drug Metab Dispos 1993 21: 1142-1146. [Abstract] [PDF]  

MC Castle

Formation of a beta-glucuronidase-resistant glucuronide conjugate of digitoxin by dog liver microsomes
Drug Metab Dispos 1993 21: 1147-1150. [Abstract] [PDF]  

RW Milne, PA Sloan, CF McLean, LE Mather, RL Nation, WB Runciman, AJ Rutten, and AA Somogyi

Disposition of morphine and its 3- and 6-glucuronide metabolites during morphine infusion in the sheep
Drug Metab Dispos 1993 21: 1151-1156. [Abstract] [PDF]  

JA Boutin, F Meunier, PH Lambert, P Hennig, D Bertin, B Serkiz, and JP Volland

In vivo and in vitro glucuronidation of the flavonoid diosmetin in rats
Drug Metab Dispos 1993 21: 1157-1166. [Abstract] [PDF]  

M Yabuki, F Shono, I Nakatsuka, and A Yoshitake

Novel cleavage of the 1,2,4-oxadiazole ring in rat metabolism of SM- 6586, a dihydropyridine calcium antagonist
Drug Metab Dispos 1993 21: 1167-1169. [PDF]  

MT Baker, WC Jr Ronnenberg, JA Ruzicka, CK Chiang, and JH Tinker

Inhibitory effects of deuterium substitution on the metabolism of sevoflurane by the rat
Drug Metab Dispos 1993 21: 1170-1171. [PDF]  

M Mayersohn and R Hamilton

Relationship between the terminal disposition half-life and mean residence time in multicompartment models
Drug Metab Dispos 1993 21: 1172-1173. [PDF]  

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