Articles:

OR Idowu, JO Peggins, TG Brewer, and C Kelley

Metabolism of a candidate 8-aminoquinoline antimalarial agent, WR 238605, by rat liver microsomes
Drug Metab Dispos 1995 23: 1-17. [Abstract] [PDF]  

OR Idowu, JO Peggins, and TG Brewer

Side-chain hydroxylation in the metabolism of 8-aminoquinoline antiparasitic agents
Drug Metab Dispos 1995 23: 18-27. [Abstract] [PDF]  

K Iwasaki, T Shiraga, H Matsuda, K Nagase, Y Tokuma, T Hata, Y Fujii, S Sakuma, T Fujitsu, and A Fujikawa

Further metabolism of FK506 (tacrolimus). Identification and biological activities of the metabolites oxidized at multiple sites of FK506
Drug Metab Dispos 1995 23: 28-34. [Abstract] [PDF]  

K Higaki, K Kamata, M Takeuchi, K Inazawa, T Chikai, T Hamaguchi, T Yukawa, K Kadono, S Kawahara, and M Nakano

Ocular absorption, distribution, and systemic absorption of a novel antiglaucoma medication, prostaglandin derivative, in male white rabbits
Drug Metab Dispos 1995 23: 35-43. [Abstract] [PDF]  

M Monshouwer, RF Witkamp, SM Nijmeijer, LA Van Leengoed, JH Verheijden, and AS Van Miert

Infection (Actinobacillus pleuropneumoniae)-mediated suppression of oxidative hepatic drug metabolism and cytochrome P4503A mRNA levels in pigs
Drug Metab Dispos 1995 23: 44-47. [Abstract] [PDF]  

E Tanaka and MW Anders

Biosynthesis of S-(2-chloro-1,1,2-trifluoroethyl)glutathione in rat and human hepatocytes and in Hep G2 cells
Drug Metab Dispos 1995 23: 48-54. [Abstract] [PDF]  

YS Kang, RJ Boado, and WM Pardridge

Pharmacokinetics and organ clearance of a 3'-biotinylated, internally [32P]-labeled phosphodiester oligodeoxynucleotide coupled to a neutral avidin/monoclonal antibody conjugate
Drug Metab Dispos 1995 23: 55-59. [Abstract] [PDF]  

MT Baker, MJ Olson, Y Wang, WC Jr Ronnenberg, JT Johnson, and AN Brady

Isoflurane-chlorodifluoroethene interaction in human liver microsomes. Role of cytochrome P4502B6 in potentiation of haloethene metabolism
Drug Metab Dispos 1995 23: 60-64. [Abstract] [PDF]  

N Chauret, C Li, Y Ducharme, LA Trimble, JA Yergey, C Ramachandran, and DA Nicoll- Griffith

In vitro and in vivo biotransformations of the naphthalenic lignan lactone 5-lipoxygenase inhibitor, L-702,539
Drug Metab Dispos 1995 23: 65-71. [Abstract] [PDF]  

JC Kraft, D Kimelman, and MR Juchau

Xenopus laevis: a model system for the study of embryonic retinoid metabolism. I. Embryonic metabolism of 9-cis- and all-trans-retinals and retinols to their corresponding acid forms
Drug Metab Dispos 1995 23: 72-82. [Abstract] [PDF]  

J Creech Kraft, D Kimelman, and MR Juchau

Xenopus laevis: a model system for the study of embryonic retinoid metabolism. II. Embryonic metabolism of all-trans-3,4-didehydroretinol to all-trans-3,4-didehydroretinoic acid
Drug Metab Dispos 1995 23: 83-89. [Abstract] [PDF]  

AJ Streeter, PL Stahle, ML Holland, JF Pritchard, and AR Takacs

Pharmacokinetics and bioavailability of topiramate in the beagle dog
Drug Metab Dispos 1995 23: 90-93. [Abstract] [PDF]  

U Renner, J Blanz, S Freund, D Waidelich, G Ehninger, and KP Zeller

Biotransformation of CI-937 in primary cultures of rat hepatocytes. Formation of glutathione conjugates
Drug Metab Dispos 1995 23: 94-101. [Abstract] [PDF]  

MK Ellis, JL Naylor, T Green, and MA Collins

Identification and quantification of fluorine-containing metabolites of 1-chloro-2,2,2-trifluoroethane (HCFC133A) in the rat by 19F-NMR spectroscopy
Drug Metab Dispos 1995 23: 102-106. [Abstract] [PDF]  

AK Nyarko and PJ Harvison

Metabolism of the nephrotoxicant N-(3,5-dichlorophenyl)succinimide by isolated rat hepatocytes
Drug Metab Dispos 1995 23: 107-112. [Abstract] [PDF]  

A Magistrelli, P Villa, E Benfenati, EJ Modest, M Salmona, and MT Tacconi

Fate of 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (ET18- OME) in malignant cells, normal cells, and isolated and perfused rat liver
Drug Metab Dispos 1995 23: 113-118. [Abstract] [PDF]  

LJ Shore, C Fenselau, AR King, and RG Dickinson

Characterization and formation of the glutathione conjugate of clofibric acid
Drug Metab Dispos 1995 23: 119-123. [Abstract] [PDF]  

MB Finkelstein, NJ Patel, and MW Anders

Metabolism of [14C]- and [35S]S-(1,2-dichlorovinyl)-L-cysteine in the male Fischer 344 rat
Drug Metab Dispos 1995 23: 124-128. [Abstract] [PDF]  

LS Tsuruda, MW Lame, and AD Jones

Metabolism of [14C]naphthalene in the B6C3F1 murine isolated perfused liver
Drug Metab Dispos 1995 23: 129-136. [Abstract] [PDF]  

G Jonsson, A Astrom, and P Andersson

Budesonide is metabolized by cytochrome P450 3A (CYP3A) enzymes in human liver
Drug Metab Dispos 1995 23: 137-142. [Abstract] [PDF]  

B Gerstenberg, G Schepers, P Voncken, and H Volkel

Nicotine and cotinine accumulation in pigmented and unpigmented rat hair
Drug Metab Dispos 1995 23: 143-148. [Abstract] [PDF]  

DJ Sweeny and HN Nellans

Stereoselective glucuronidation of zileuton isomers by human hepatic microsomes
Drug Metab Dispos 1995 23: 149-153. [Abstract] [PDF]  

DJ Newton, RW Wang, and AY Lu

Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes
Drug Metab Dispos 1995 23: 154-158. [Abstract] [PDF]  

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