Reviews:

JH Lin

Species similarities and differences in pharmacokinetics
Drug Metab Dispos 1995 23: 1008-1021. [Abstract] [PDF]  

Articles:

M Hosokawa, T Endo, M Fujisawa, S Hara, N Iwata, Y Sato, and T Satoh

Interindividual variation in carboxylesterase levels in human liver microsomes
Drug Metab Dispos 1995 23: 1022-1027. [Abstract] [PDF]  

CB Davis, TW Hepburn, JJ Urbanski, DC Kwok, TK Hart, DJ Herzyk, SG Demuth, M Leland, and GR Rhodes

Preclinical pharmacokinetic evaluation of the respiratory syncytial virus-specific reshaped human monoclonal antibody RSHZ19
Drug Metab Dispos 1995 23: 1028-1036. [Abstract] [PDF]  

PJ Castle, JL Merdink, JR Okita, SA Wrighton, and RT Okita

Human liver lauric acid hydroxylase activities
Drug Metab Dispos 1995 23: 1037-1043. [Abstract] [PDF]  

TW Hepburn, CB Davis, JJ Urbanski, BR Smith, WH Schaefer, MA Carbonaro, and PJ Bugelski

Renal catabolism of recombinant human soluble CD4 after intravenous administration to male Sprague-Dawley rats
Drug Metab Dispos 1995 23: 1044-1050. [Abstract] [PDF]  

B Valles, CD Schiller, P Coassolo, G De Sousa, R Wyss, D Jaeck, A Viger- Chougnet, and R Rahmani

Metabolism of mofarotene in hepatocytes and liver microsomes from different species. Comparison with in vivo data and evaluation of the cytochrome P450 isoenzymes involved in human biotransformation
Drug Metab Dispos 1995 23: 1051-1057. [Abstract] [PDF]  

JC Kraft and MR Juchau

Xenopus laevis: a model system for the study of embryonic retinoid metabolism. III. Isomerization and metabolism of all-trans-retinoic acid and 9-cis-retinoic acid and their dysmorphogenic effects in embryos during neurulation
Drug Metab Dispos 1995 23: 1058-1071. [Abstract] [PDF]  

MI Davies and CE Lunte

Microdialysis sampling for hepatic metabolism studies. Impact of microdialysis probe design and implantation technique on liver tissue
Drug Metab Dispos 1995 23: 1072-1079. [Abstract] [PDF]  

L Sreerama and NE Sladek

Human breast adenocarcinoma MCF-7/0 cells electroporated with cytosolic class 3 aldehyde dehydrogenases obtained from tumor cells and a normal tissue exhibit differential sensitivity to mafosfamide
Drug Metab Dispos 1995 23: 1080-1084. [Abstract] [PDF]  

DA Nicoll-Griffith, N Gupta, SP Twa, H Williams, LA Trimble, and JA Yergey

Verlukast (MK-0679) conjugation with glutathione by rat liver and kidney cytosols and excretion in the bile
Drug Metab Dispos 1995 23: 1085-1093. [Abstract] [PDF]  

SG Sastry, RA Sanders, JC Veltman, and JB 3rd Watkins

Minimal effects of two aldose reductase inhibitors, AL-1576 and AL- 4114, after subacute topical-ocular dosing on xenobiotic biotransformation in rabbits
Drug Metab Dispos 1995 23: 1094-1098. [Abstract] [PDF]  

M Iwaki, A Bischer, AC Nguyen, AF McDonagh, and LZ Benet

Stereoselective disposition of naproxen glucuronide in the rat
Drug Metab Dispos 1995 23: 1099-1103. [Abstract] [PDF]  

KE Zhang and KP Vyas

Disposition of DMP 811 (L-708,404), a potent angiotensin II receptor antagonist, in the rat, monkey, and chimpanzee
Drug Metab Dispos 1995 23: 1104-1109. [Abstract] [PDF]  

DJ Murry, WR Crom, WE Reddick, R Bhargava, and WE Evans

Liver volume as a determinant of drug clearance in children and adolescents
Drug Metab Dispos 1995 23: 1110-1116. [Abstract] [PDF]  

RJ Bergeron, WR Weimar, G Luchetta, RR Streiff, J Wiegand, J Perrin, KM Schreier, C Porter, GW Yao, and H Dimova

Metabolism and pharmacokinetics of N1,N11-diethylnorspermine
Drug Metab Dispos 1995 23: 1117-1125. [Abstract] [PDF]  

SW Huskey, DC Dean, RR Miller, GH Rasmusson, and SH Chiu

Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride [published erratum appears in Drug Metab Dispos 1996 Jun;24(6):695]
Drug Metab Dispos 1995 23: 1126-1135. [Abstract] [PDF]  

SS Lau, HE Kleiner, and TJ Monks

Metabolism as a determinant of species susceptibility to 2,3,5- (triglutathion-S-yl)hydroquinone-mediated nephrotoxicity. The role of N- acetylation and N-deacetylation
Drug Metab Dispos 1995 23: 1136-1142. [Abstract] [PDF]  

AD Rodrigues, MJ Kukulka, JL Ferrero, and JR Cashman

In vitro hepatic metabolism of ABT-418 in chimpanzee (Pan troglodytes). A unique pattern of microsomal flavin-containing monooxygenase- dependent stereoselective N'-oxidation
Drug Metab Dispos 1995 23: 1143-1152. [Abstract] [PDF]  

A Madan, A Parkinson, and MD Faiman

Identification of the human and rat P450 enzymes responsible for the sulfoxidation of S-methyl N,N-diethylthiolcarbamate (DETC-ME). The terminal step in the bioactivation of disulfiram
Drug Metab Dispos 1995 23: 1153-1162. [Abstract] [PDF]  

JM Machinist, MD Mayer, MS Shet, JL Ferrero, and AD Rodrigues

Identification of the human liver cytochrome P450 enzymes involved in the metabolism of zileuton (ABT-077) and its N-dehydroxylated metabolite, Abbott-66193
Drug Metab Dispos 1995 23: 1163-1174. [Abstract] [PDF]  

PA Crooks, M Li, and LP Dwoskin

Determination of nicotine metabolites in rat brain after peripheral radiolabeled nicotine administration: detection of nornicotine
Drug Metab Dispos 1995 23: 1175-1177. [PDF]  

RA Yokel, AM Fredenburg, KA Meurer, and TL Skinner

Influence of lipophilicity on the bioavailability and disposition of orally active 3-hydroxypyridin-4-one metal chelators
Drug Metab Dispos 1995 23: 1178-1180. [PDF]  

Letters:

S Vickers

Use of gender and oxygenation as synonyms for sex and oxidation [letter]
Drug Metab Dispos 1995 23: 1007. [PDF]  

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