Articles:

MD Green, WP Bishop, and TR Tephly

Expressed human UGT1.4 protein catalyzes the formation of quaternary ammonium-linked glucuronides
Drug Metab Dispos 1995 23: 299-302. [Abstract] [PDF]  

RE Kane, AP Li, and DR Kaminski

Sulfation and glucuronidation of acetaminophen by human hepatocytes cultured on Matrigel and type 1 collagen reproduces conjugation in vivo
Drug Metab Dispos 1995 23: 303-307. [Abstract] [PDF]  

F Nicolas, G De Sousa, P Thomas, M Placidi, G Lorenzon, and R Rahmani

Comparative metabolism of 3'-azido-3'-deoxythymidine in cultured hepatocytes from rats, dogs, monkeys, and humans
Drug Metab Dispos 1995 23: 308-313. [Abstract] [PDF]  

R Choudhury and S Singh

Effect of iron overload on the metabolism and urinary recovery of 3- hydroxypyridin-4-one chelating agents in the rat
Drug Metab Dispos 1995 23: 314-320. [Abstract] [PDF]  

AE Vickers, E Meyer, R Dannecker, B Keller, RE Tynes, and G Maurer

Human liver cytochrome P4503A biotransformation of the cyclosporin derivative SDZ IMM 125
Drug Metab Dispos 1995 23: 321-326. [Abstract] [PDF]  

AE Vickers, RL Fisher, K Brendel, J Guertler, R Dannecker, B Keller, and V Fischer

Sites of biotransformation for the cyclosporin derivative SDZ IMM 125 using human liver and kidney slices and intestine. Comparison with rat liver slices and cyclosporin A metabolism
Drug Metab Dispos 1995 23: 327-333. [Abstract] [PDF]  

RW Milne, CF McLean, LE Mather, RL Nation, WB Runciman, AJ Rutten, and AA Somogyi

Comparative disposition of morphine-3-glucuronide during separate intravenous infusions of morphine and morphine-3-glucuronide in sheep. Importance of the kidney
Drug Metab Dispos 1995 23: 334-342. [Abstract] [PDF]  

M Hamdoune, J Mounie, J Magdalou, T Masmoudi, H Goudonnet, and A Escousse

Characterization of the in vitro glucuronidation of flurbiprofen enantiomers
Drug Metab Dispos 1995 23: 343-348. [Abstract] [PDF]  

KA Hayes, B Brennan, R Chenery, and JB Houston

In vivo disposition of caffeine predicted from hepatic microsomal and hepatocyte data
Drug Metab Dispos 1995 23: 349-353. [Abstract] [PDF]  

K Lavrijsen, D van Dyck, J van Houdt, J Hendrickx, J Monbaliu, R Woestenborghs, W Meuldermans, and J Heykants

Reduction of the prodrug loperamide oxide to its active drug loperamide in the gut of rats, dogs, and humans
Drug Metab Dispos 1995 23: 354-362. [Abstract] [PDF]  

LK Webster, AG Ellis, P Kestell, and GW Rewcastle

Metabolism and elimination of 5,6-dimethylxanthenone-4-acetic acid in the isolated perfused rat liver
Drug Metab Dispos 1995 23: 363-368. [Abstract] [PDF]  

A Ding, P Zia-Amirhosseini, AF McDonagh, AL Burlingame, and LZ Benet

Reactivity of tolmetin glucuronide with human serum albumin. Identification of binding sites and mechanisms of reaction by tandem mass spectrometry
Drug Metab Dispos 1995 23: 369-376. [Abstract] [PDF]  

GK Poon, B Walter, PE Lonning, MN Horton, and R McCague

Identification of tamoxifen metabolites in human Hep G2 cell line, human liver homogenate, and patients on long-term therapy for breast cancer
Drug Metab Dispos 1995 23: 377-382. [Abstract] [PDF]  

LC Wienkers, RC Steenwyk, SA Mizsak, and PG Pearson

In vitro metabolism of tirilazad mesylate in male and female rats. Contribution of cytochrome P4502C11 and delta 4-5 alpha-reductase
Drug Metab Dispos 1995 23: 383-392. [Abstract] [PDF]  

PD Worboys, A Bradbury, and JB Houston

Kinetics of drug metabolism in rat liver slices. Rates of oxidation of ethoxycoumarin and tolbutamide, examples of high- and low-clearance compounds
Drug Metab Dispos 1995 23: 393-397. [Abstract] [PDF]  

D Lee, C Szumlanski, J Houtman, R Honchel, K Rojas, J Overhauser, ED Wieben, and RM Weinshilboum

Thiopurine methyltransferase pharmacogenetics. Cloning of human liver cDNA and a processed pseudogene on human chromosome 18q21.1
Drug Metab Dispos 1995 23: 398-405. [Abstract] [PDF]  

AE Cribb, SP Spielberg, and GP Griffin

N4-hydroxylation of sulfamethoxazole by cytochrome P450 of the cytochrome P4502C subfamily and reduction of sulfamethoxazole hydroxylamine in human and rat hepatic microsomes
Drug Metab Dispos 1995 23: 406-414. [Abstract] [PDF]  

TA Kocarek, EG Schuetz, SC Strom, RA Fisher, and PS Guzelian

Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human hepatocytes
Drug Metab Dispos 1995 23: 415-421. [Abstract] [PDF]  

MW Lame, AD Jones, D Morin, HJ Segall, and DW Wilson

Biliary excretion of pyrrolic metabolites of [14C]monocrotaline in the rat
Drug Metab Dispos 1995 23: 422-429. [Abstract] [PDF]  

K Inoue and CR Creveling

Induction of catechol-O-methyltransferase in the luminal epithelium of rat uterus by progesterone: inhibition by RU-486
Drug Metab Dispos 1995 23: 430-432. [PDF]  

MS Highley, G Momerency, K Van Cauwenberghe, AT Van Oosterom, EA de Bruijn, RA Maes, P Blake, J Mansi, and PG Harper

Formation of chloroethylamine and 1,3-oxazolidine-2-one following ifosfamide administration in humans
Drug Metab Dispos 1995 23: 433-437. [PDF]  

H Yamazaki, Z Guo, and FP Guengerich

Selectivity of cytochrome P4502E1 in chlorzoxazone 6-hydroxylation
Drug Metab Dispos 1995 23: 438-440. [PDF]  

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