Articles:

KJ Nikula, RF Novak, IY Chang, AR Dahl, DA Kracko, RC Zangar, SG Kim, and JL Lewis

Induction of nasal carboxylesterase in F344 rats following inhalation exposure to pyridine
Drug Metab Dispos 1995 23: 529-535. [Abstract] [PDF]  

MR Anari, AE Cribb, and KW Renton

The duration of induction and species influences the downregulation of cytochrome P450 by the interferon inducer polyinosinic acid- polycytidylic acid
Drug Metab Dispos 1995 23: 536-541. [Abstract] [PDF]  

RF Witkamp, SM Nijmeijer, M Monshouwer, and AS Van Miert

The antibiotic tiamulin is a potent inducer and inhibitor of cytochrome P4503A via the formation of a stable metabolic intermediate complex. Studies in primary hepatocyte cultures and liver microsomes of the pig
Drug Metab Dispos 1995 23: 542-547. [Abstract] [PDF]  

SM Neighbors and WH Soine

Identification of phenobarbital N-glucuronides as urinary metabolites of phenobarbital in mice
Drug Metab Dispos 1995 23: 548-552. [Abstract] [PDF]  

MT Donato, JV Castell, and MJ Gomez-Lechon

Effect of model inducers on cytochrome P450 activities of human hepatocytes in primary culture
Drug Metab Dispos 1995 23: 553-558. [Abstract] [PDF]  

LE Lemke and CA McQueen

Acetylation and its role in the mutagenicity of the antihypertensive agent hydralazine
Drug Metab Dispos 1995 23: 559-565. [Abstract] [PDF]  

M Castillo and PC Smith

Disposition and reactivity of ibuprofen and ibufenac acyl glucuronides in vivo in the rhesus monkey and in vitro with human serum albumin
Drug Metab Dispos 1995 23: 566-572. [Abstract] [PDF]  

AA Fasanmade and WJ Jusko

An improved pharmacodynamic model for formation of methemoglobin by antimalarial drugs
Drug Metab Dispos 1995 23: 573-576. [Abstract] [PDF]  

SW Grimm, JR Bend, and JR Halpert

Selectivity and kinetics of inactivation of rabbit hepatic cytochromes P450 2B4 and 2B5 by N-aralkylated derivatives of 1-aminobenzotriazole
Drug Metab Dispos 1995 23: 577-583. [Abstract] [PDF]  

C Abdallah, JG Besner, and P Du Souich

Presystemic elimination of morphine in anesthetized rabbits. Contribution of the intestine, liver, and lungs
Drug Metab Dispos 1995 23: 584-589. [Abstract] [PDF]  

SM Furst, P Sukhai, RA McClelland, and JP Uetrecht

Covalent binding of carbamazepine oxidative metabolites to neutrophils
Drug Metab Dispos 1995 23: 590-594. [Abstract] [PDF]  

WK Nichols, CM Terry, NS Cutler, ML Appleton, PK Jesthi, and GS Yost

Oxidation at C-1 controls the cytotoxicity of 1,1-dichloro-2,2- bis(p- chlorophenyl)ethane by rabbit and human lung cells
Drug Metab Dispos 1995 23: 595-599. [Abstract] [PDF]  

LE Richards and JH Sun

Identification of two regioisomeric monocarboxylic acid metabolites of losoxantrone (DuP 941; Biantrazole) excreted in human urine
Drug Metab Dispos 1995 23: 600-602. [PDF]  

RP Kapil and GN Lam

Pharmacokinetics and presystemic hepatic first-pass elimination of a novel sigma receptor antagonist, DuP 734, in the rat
Drug Metab Dispos 1995 23: 603-606. [PDF]  

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