Articles:

JP Jones, M He, WF Trager, and AE Rettie

Three-dimensional quantitative structure-activity relationship for inhibitors of cytochrome P4502C9
Drug Metab Dispos 1996 24: 1-6. [PDF]  

Y Singh, JB Cooke, DE Hinton, and MG Miller

Trout liver slices for metabolism and toxicity studies
Drug Metab Dispos 1996 24: 7-14. [Abstract] [PDF]  

A Gruebele, K Zawaski, D Kaplan, and RF Novak

Cytochrome P4502E1- and cytochrome P4502B1/2B2-catalyzed carbon tetrachloride metabolism: effects on signal transduction as demonstrated by altered immediate-early (c-Fos and c-Jun) gene expression and nuclear AP-1 and NF-kappa B transcription factor levels
Drug Metab Dispos 1996 24: 15-22. [Abstract] [PDF]  

XJ Zhang and PE Thomas

Erythromycin as a specific substrate for cytochrome P4503A isozymes and identification of a high-affinity erythromycin N-demethylase in adult female rats
Drug Metab Dispos 1996 24: 23-27. [Abstract] [PDF]  

LE Los, DA Welsh, EG Herold, WJ Bagdon, and AG Zacchei

Gender differences in toxicokinetics, liver metabolism, and plasma esterase activity: observations from a chronic (27-week) toxicity study of enalapril/diltiazem combinations in rats
Drug Metab Dispos 1996 24: 28-33. [Abstract] [PDF]  

JP Chism and DE Rickert

The pharmacokinetics and extra-hepatic clearance of remifentanil, a short acting opioid agonist, in male beagle dogs during constant rate infusions
Drug Metab Dispos 1996 24: 34-40. [Abstract] [PDF]  

G Birner, A Rutkowska, and W Dekant

N-acetyl-S-(1,2,2-trichlorovinyl)-L-cysteine and 2,2,2- trichloroethanol: two novel metabolites of tetrachloroethene in humans after occupational exposure
Drug Metab Dispos 1996 24: 41-48. [Abstract] [PDF]  

T Furuta, K Okamiya, H Shibasaki, and Y Kasuya

Pharmacokinetics of stable isotopically labeled L-histidine in humans and the assessment of in vivo histidine ammonia lyase activities
Drug Metab Dispos 1996 24: 49-54. [Abstract] [PDF]  

AR Taylor, RD Brownsill, H Grandon, F Lefoulon, A Petit, W Luijten, PG Kopelman, and B Walther

Synthesis of putative metabolites and investigation of the metabolic fate of gliclazide, [1-(3-azabicyclo(3,3,0)oct-3-yl)-3-(4- methylphenylsulfonyl) urea], in diabetic patients
Drug Metab Dispos 1996 24: 55-64. [Abstract] [PDF]  

JG Slatter, KL Feenstra, MJ Hauer, DA Kloosterman, AH Parton, PE Sanders, G Scott, and W Speed

Metabolism of the bisphosphonate ester U-91502 in rats
Drug Metab Dispos 1996 24: 65-73. [Abstract] [PDF]  

TS Poet, CA McQueen, and JR Halpert

Participation of cytochromes P4502B and P4503A in cocaine toxicity in rat hepatocytes
Drug Metab Dispos 1996 24: 74-80. [Abstract] [PDF]  

YC Ni, TY Wong, RV Lloyd, TM Heinze, S Shelton, D Casciano, FF Kadlubar, and PP Fu

Mouse liver microsomal metabolism of chloral hydrate, trichloroacetic acid, and trichloroethanol leading to induction of lipid peroxidation via a free radical mechanism
Drug Metab Dispos 1996 24: 81-90. [Abstract] [PDF]  

RH Barbhaiya, KA Dandekar, and DS Greene

Pharmacokinetics, absolute bioavailability, and disposition of [14C]nefazodone in humans
Drug Metab Dispos 1996 24: 91-95. [Abstract] [PDF]  

BS Kuo, GD Nordblom, RC Dudeck, LS Kirkish, and DS Wright

Disposition kinetics of human epidermal growth factor (hEGF1-53) and its truncated fragment (hEGF1-48) in rats
Drug Metab Dispos 1996 24: 96-104. [Abstract] [PDF]  

RA Yokel, KA Meurer, TL Skinner, and AM Fredenburg

The 3-hydroxypyridin-4-ones more effectively chelate aluminum in a rabbit model of aluminum intoxication than does desferrioxamine
Drug Metab Dispos 1996 24: 105-111. [Abstract] [PDF]  

N Bichara, MS Ching, CL Blake, H Ghabrial, and RA Smallwood

Propranolol hydroxylation and N-desisopropylation by cytochrome P4502D6: studies using the yeast-expressed enzyme and NADPH/O2 and cumene hydroperoxide-supported reactions
Drug Metab Dispos 1996 24: 112-118. [Abstract] [PDF]  

DJ Smith, ML Appleton, JR Carlson, and GS Yost

Identification of beta-glucuronidase-resistant diastereomeric glucuronides of 3-hydroxy-3-methyloxindole formed during 3-methylindole metabolism in goats
Drug Metab Dispos 1996 24: 119-125. [Abstract] [PDF]  

AD Rodrigues, MJ Kukulka, EM Roberts, D Ouellet, and TR Rodgers

[O-methyl 14C]naproxen O-demethylase activity in human liver microsomes: evidence for the involvement of cytochrome P4501A2 and P4502C9/10
Drug Metab Dispos 1996 24: 126-136. [Abstract] [PDF]  

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