DMD Noab BioDiscoveries - Shaping Drug Discovery

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June 1996; 24 (6)   [Index by Author]       Other Issues:  
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Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF)
To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Articles:

SK Panesar, SM Bandiera, and FS Abbott
Comparative effects of carbamazepine and carbamazepine-10,11-epoxide on hepatic cytochromes P450 in the rat
Drug Metab Dispos 1996 24: 619-627. [Abstract] [PDF]  

WP McNally, WF Pool, MW Sinz, P Dehart, DF Ortwine, CC Huang, T Chang, and TF Woolf
Distribution of tacrine and metabolites in rat brain and plasma after single- and multiple-dose regimens. Evidence for accumulation of tacrine in brain tissue
Drug Metab Dispos 1996 24: 628-633. [Abstract] [PDF]  

T Prueksaritanont, LM Gorham, JH Hochman, LO Tran, and KP Vyas
Comparative studies of drug-metabolizing enzymes in dog, monkey, and human small intestines, and in Caco-2 cells
Drug Metab Dispos 1996 24: 634-642. [Abstract] [PDF]  

SL Nyberg, HJ Mann, MY Hu, WD Payne, WS Hu, FB Cerra, and RP Remmel
Extrahepatic metabolism of 4-methylumbelliferone and lidocaine in the anhepatic rabbit
Drug Metab Dispos 1996 24: 643-648. [Abstract] [PDF]  

ED Kharasch and DC Hankins
P450-dependent and nonenzymatic human liver microsomal defluorination of fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A), a sevoflurane degradation product
Drug Metab Dispos 1996 24: 649-654. [Abstract] [PDF]  

A Sparreboom, O Van Tellingen, EJ Scherrenburg, JJ Boesen, MT Huizing, WJ Nooijen, C Versluis, and JH Beijnen
Isolation, purification and biological activity of major docetaxel metabolites from human feces
Drug Metab Dispos 1996 24: 655-658. [Abstract] [PDF]  

BK Wong, PJ Bruhin, A Barrish, and JH Lin
Nonlinear dorzolamide pharmacokinetics in rats: concentration-dependent erythrocyte distribution and drug-metabolite displacement interaction
Drug Metab Dispos 1996 24: 659-663. [Abstract] [PDF]  

RM Laethem, M Balazy, and DR Koop
Epoxidation of C18 unsaturated fatty acids by cytochromes P4502C2 and P4502CAA
Drug Metab Dispos 1996 24: 664-668. [Abstract] [PDF]  

U Sharma, ES Roberts, and PF Hollenberg
Inactivation of cytochrome P4502B1 by the monoamine oxidase inhibitors R-(-)-deprenyl and clorgyline
Drug Metab Dispos 1996 24: 669-675. [Abstract] [PDF]  

PD Worboys, A Bradbury, and JB Houston
Kinetics of drug metabolism in rat liver slices. II. Comparison of clearance by liver slices and freshly isolated hepatocytes
Drug Metab Dispos 1996 24: 676-681. [Abstract] [PDF]  

Z Gregus, T Fekete, E Halaszi, and CD Klaassen
Lipoic acid impairs glycine conjugation of benzoic acid and renal excretion of benzoylglycine
Drug Metab Dispos 1996 24: 682-688. [Abstract] [PDF]  

S Vidrequin, F Gimenez, LK Basco, C Martin, J LeBras, and R Farinotti
Uptake of mefloquine enantiomers into uninfected and malaria-infected erythrocytes
Drug Metab Dispos 1996 24: 689-691. [PDF]  

MS Ching, N Bichara, CL Blake, H Ghabrial, RH Tukey, and RA Smallwood
Propranolol 4- and 5-hydroxylation and N-desisopropylation by cloned human cytochrome P4501A1 and P4501A2
Drug Metab Dispos 1996 24: 692-694. [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


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