Noab BioDiscoveries - Shaping Drug Discovery

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April 1997; 25 (4)   [Index by Author]       Other Issues:  
       Articles
       Short Communications
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To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Articles:

Aline Salvi, Pierre-Alain Carrupt, Joachim M. Mayer, and Bernard Testa
Esterase-like Activity of Human Serum Albumin Toward Prodrug Esters of Nicotinic Acid
Drug Metab Dispos 1997 25: 395-398. [Abstract] [Full Text] [PDF]  

Liping Chen, Jeroen T. M. Buters, James P. Hardwick, Shingi Tamura, Bruce W. Penman, Frank J. Gonzalez, and Charles L. Crespi
Coexpression of Cytochrome P4502A6 and Human NADPH-P450 Oxidoreductase in the Baculovirus System
Drug Metab Dispos 1997 25: 399-405. [Abstract] [Full Text] [PDF]  

Eric Battaglia, Susan Nowell, Richard R. Drake, Jacques Magdalou, Sylvie Fournel-Gigleux, Claire Senay, and Anna Radominska
Photoaffinity Labeling Studies of the Human Recombinant UDP-Glucuronosyltransferase, UGT1*6, with 5-Azido-UDP-Glucuronic Acid
Drug Metab Dispos 1997 25: 406-411. [Abstract] [Full Text] [PDF]  

Hsiao-Hui Chow, Ping Li, Gary Brookshier, and Yang Tang
In Vivo Tissue Disposition of 3'-Azido-3'-deoxythymidine and Its Anabolites in Control and Retrovirus-Infected Mice
Drug Metab Dispos 1997 25: 412-422. [Abstract] [Full Text] [PDF]  

Deepak K. Dalvie, Natasha Khosla, and John Vincent
Excretion and Metabolism of Trovafloxacin in Humans
Drug Metab Dispos 1997 25: 423-427. [Abstract] [Full Text] [PDF]  

Stéphane L. Eeckhoudt, Pierre A. Evrard, and Roger K. Verbeeck
Biliary Excretion and Enterohepatic Cycling of R- and S-Flurbiprofen in the Rat
Drug Metab Dispos 1997 25: 428-430. [Abstract] [Full Text] [PDF]  

Zhengrong Yu, William L. Hayton, and Kenneth K. Chan
Characterization of Proflavine Metabolites in Rainbow Trout
Drug Metab Dispos 1997 25: 431-436. [Abstract] [Full Text] [PDF]  

James P. McNamee, Malle Jurima-Romet, Susan M. Kobus, and Gerald S. Marks
cDNA-Expressed Human Cytochrome P450 Isozymes. Inactivation by Porphyrinogenic Xenobiotics
Drug Metab Dispos 1997 25: 437-441. [Abstract] [Full Text] [PDF]  

Monika Dahms, Ralf Lotz, Werner Lang, Ulf Renner, Ernst Bayer, and Hildegard Spahn-Langguth
Elucidation of Phase I and Phase II Metabolic Pathways of Rhein: Species Differences and Their Potential Relevance
Drug Metab Dispos 1997 25: 442-452. [Abstract] [Full Text] [PDF]  

Tucker A. Patterson, Zbigniew K. Binienda, George W. Lipe, Michael P. Gillam, William Slikker, Jr., and Jennifer A. Sandberg
Transplacental Pharmacokinetics and Fetal Distribution of Azidothymidine, Its Glucuronide, and Phosphorylated Metabolites in Late-Term Rhesus Macaques after Maternal Infusion
Drug Metab Dispos 1997 25: 453-459. [Abstract] [Full Text] [PDF]  

Philip D. Worboys, Alan Bradbury, and J. Brian Houston
Kinetics of Drug Metabolism in Rat Liver Slices. III. Relationship between Metabolic Clearance and Slice Uptake Rate
Drug Metab Dispos 1997 25: 460-467. [Abstract] [Full Text] [PDF]  

Herbert J. Sipe, Jr., Jean T. Corbett, and Ronald P. Mason
In vitro free radical metabolism of phenolphthalein by peroxidases
Drug Metab Dispos 1997 25: 468-480. [Abstract] [Full Text] [PDF]  

Vijaya M. Lakshmi, Terry V. Zenser, and Bernard B. Davis
Rat Liver Cytochrome P450 Metabolism of N-Acetylbenzidine and N,N'-Diacetylbenzidine
Drug Metab Dispos 1997 25: 481-488. [Abstract] [Full Text] [PDF]  

Jon F. Denissen, Brian A. Grabowski, Marianne K. Johnson, Alex M. Buko, Dale J. Kempf, Samuel B. Thomas, and Bruce W. Surber
Metabolism And Disposition of the HIV-1 Protease Inhibitor Ritonavir (ABT-538) in Rats, Dogs, and Humans
Drug Metab Dispos 1997 25: 489. [Abstract] [Full Text] [PDF]  

Regina W. Wang, Deborah J. Newton, Tad D. Scheri, and Anthony Y. H. Lu
Human Cytochrome P450 3A4-Catalyzed Testosterone 6beta -Hydroxylation and Erythromycin N-Demethylation. Competition During Catalysis
Drug Metab Dispos 1997 25: 502-507. [Abstract] [Full Text] [PDF]  

Lars W. Wormhoudt, Jan N. M. Commandeur, Jan H. T. M. Ploemen, Ruben S. Abdoelgafoer, Arman Makansi, Peter J. van Bladeren, and Nico P. E. Vermeulen
Urinary Thiodiacetic Acid. A Selective Biomarker for the Cytochrome P450-Catalyzed Oxidation of 1,2-Dibromoethane in the Rat
Drug Metab Dispos 1997 25: 508-515. [Abstract] [Full Text] [PDF]  

Rudolfs K. Zalups and Lawrence H. Lash
Depletion of glutathione in the Kidney and the Renal Disposition of Administered Inorganic Mercury
Drug Metab Dispos 1997 25: 516-523. [Abstract] [Full Text] [PDF]  

Short Communications:

Meera Tugnait, Edward M. Hawes, Gordon McKay, Allan E. Rettie, Robert L. Haining, and Kamal K. Midha
N-Oxygenation of Clozapine by Flavin-Containing Monooxygenase
Drug Metab Dispos 1997 25: 524-527. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


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