Noab BioDiscoveries - Shaping Drug Discovery

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October 1998; 26 (10)   [Index by Author]       Other Issues:  
       Articles
       Short Communications
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To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Articles:

B. V. Karanam, R. R. Miller, A. Colletti, T. Montgomery, K. D. Carey, T. Hawkins, Y. S. Tang, M. Lavin, R. A. Stearns, S. H. L. Chiu, and S. H. Vincent
Disposition of L-732,531, a Potent Immunosuppressant, in Rats and Baboons
Drug Metab Dispos 1998 26: 949-957. [Abstract] [Full Text] [PDF]  

William H. Schaefer, James Politowski, Bruce Hwang, Frank Dixon Jr., Anne Goalwin, Louis Gutzait, Kathleen Anderson, Charles DeBrosse, Mark Bean, and Gerald R. Rhodes
Metabolism of Carvedilol in Dogs, Rats, and Mice
Drug Metab Dispos 1998 26: 958-969. [Abstract] [Full Text] [PDF]  

Joseph M. Machinist, Michael D. Mayer, Ellen M. Roberts, Bruce W. Surber, and A. David Rodrigues
Identification of the Human Liver Cytochrome P450 Enzymes Involved in the In Vitro Metabolism of a Novel 5-Lipoxygenase Inhibitor
Drug Metab Dispos 1998 26: 970-976. [Abstract] [Full Text] [PDF]  

Marjan Motie, Katie W. Schaul, and Lawrence A. Potempa
Biodistribution and Clearance of 125I-Labeled C-Reactive Protein and 125I-Labeled Modified C-Reactive Protein in CD-1 Mice
Drug Metab Dispos 1998 26: 977-981. [Abstract] [Full Text] [PDF]  

Meihua Rose Feng, Joseph Loo, and Jonathan Wright
Disposition of the Antipsychotic Agent CI-1007 in Rats, Monkeys, Dogs, and Human Cytochrome P450 2D6 Extensive Metabolizers. Species Comparison and Allometric Scaling
Drug Metab Dispos 1998 26: 982-988. [Abstract] [Full Text] [PDF]  

Suoping Zhai, Renke Dai, Fred K. Friedman, and Robert E. Vestal
Comparative Inhibition of Human Cytochromes P450 1A1 and 1A2 by Flavonoids
Drug Metab Dispos 1998 26: 989-992. [Abstract] [Full Text] [PDF]  

Shih-Jung Lan, Dolly C. Hsieh, John W. Hillyer, R. Marcus Fancher, Kent J. Rinehart, Bethanne M. Warrack, and Ronald E. White
Metabolism of alpha -Phosphonosulfonate Squalene Synthase Inhibitors. I. Disposition of a Farnesylethyl alpha -Phosphonosulfonate and Ester Prodrugs in Rats
Drug Metab Dispos 1998 26: 993-1000. [Abstract] [Full Text] [PDF]  

Jingqi Bao, John-Michael Sauer, Richard L. Smith, Robert K. Kuester, Margaret J. Kattnig, and I. Glenn Sipes
Sulfhydryl-Dependent Biotransformation and Macromolecular Binding of 1,2-Dibromo-2,4-Dicyanobutane in Blood
Drug Metab Dispos 1998 26: 1001-1007. [Abstract] [Full Text] [PDF]  

Mayland Chang, Virendra K. Sood, Gracella J. Wilson, David A. Kloosterman, Phillip E. Sanders, Margaret R. Schuette, Ray W. Judy, Richard L. Voorman, Stephen M. Maio, and J. Greg Slatter
Absorption, Distribution, Metabolism, and Excretion of Atevirdine in the Rat
Drug Metab Dispos 1998 26: 1008-1018. [Abstract] [Full Text] [PDF]  

Peter R. Sinclair, Nadia Gorman, Ilya B. Tsyrlov, Uwe Fuhr, Heidi S. Walton, and Jacqueline F. Sinclair
Uroporphyrinogen Oxidation Catalyzed by Human Cytochromes P450
Drug Metab Dispos 1998 26: 1019-1025. [Abstract] [Full Text] [PDF]  

Yasuna Kobayashi, Sharon M. Strobel, Nancy Eddy Hopkins, William L. Alworth, and James R. Halpert
Catalytic Properties of an Expressed Cytochrome P450 2b1 From a Wistar-Kyoto Rat Liver cdna Library
Drug Metab Dispos 1998 26: 1026-1030. [Abstract] [Full Text] [PDF]  

Mellissa D. Anderson, Stelvio M. Bandiera, Thomas K. H. Chang, and Gail D. Bellward
Effect of Androgen Administration During Puberty on Hepatic CYP2C11, CYP3A, and CYP2A1 Expression in Adult Female Rats
Drug Metab Dispos 1998 26: 1031-1038. [Abstract] [Full Text] [PDF]  

Short Communications:

Mariana K. Martinasevic, Christopher D. King, Gladys R. Rios, and Thomas R. Tephly
Immunohistochemical Localization of UDP-Glucuronosyltransferases in Rat Brain During Early Development
Drug Metab Dispos 1998 26: 1039-1041. [Abstract] [Full Text] [PDF]  

Heinrich Iber and Edward T. Morgan
Regulation of Hepatic Cytochrome P450 2C11 by Transforming Growth Factor-beta , Hepatocyte Growth Factor, and Interleukin-11
Drug Metab Dispos 1998 26: 1042-1044. [Abstract] [Full Text] [PDF]  

Tamihide Matsunaga, Nobuyuki Kishi, Hiroyuki Tanaka, Kazuhito Watanabe, Hidetoshi Yoshimura, and Ikuo Yamamoto
Major Cytochrome P450 Enzyme Responsible for Oxidation of Secondary Alcohols to the Corresponding Ketones in Mouse Hepatic Microsomes. Oxidation of 7-Hydroxy-Delta 8-tetrahydrocannabinol to 7-Oxo-Delta 8-tetrahydrocannabinol
Drug Metab Dispos 1998 26: 1045-1047. [Abstract] [Full Text] [PDF]  

Michael A. Wynalda, Michael J. Hauer, and Larry C. Wienkers
Human Biotransformation of Bropirimine. Characterization of the Major Bropirimine Oxidative Metabolites Formed In Vitro
Drug Metab Dispos 1998 26: 1048-1051. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


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