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June 1998; 26 (6)   [Index by Author]       Other Issues:  
       Articles
       Short Communications
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To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Articles:

Mitchell D. Green, Christopher D. King, Behnaz Mojarrabi, Peter I. Mackenzie, and Thomas R. Tephly
Glucuronidation of Amines and Other Xenobiotics Catalyzed by Expressed Human UDP-Glucuronosyltransferase 1A3
Drug Metab Dispos 1998 26: 507-512. [Abstract] [Full Text] [PDF]  

Neil R. Hartman, K. U. Leo, T. G. Brewer, and J. M. Strong
The In Vitro Metabolism of Penclomedine in Mouse, Rat, and Human Systems
Drug Metab Dispos 1998 26: 513-519. [Abstract] [Full Text] [PDF]  

Thomayant Prueksaritanont, Polly DeLuna, Lynn M. Gorham, Bennett Ma, Dosinda Cohn, Jianmei Pang, Xin Xu, Kwan Leung, and Jiunn H. Lin
In Vitro and In Vivo Evaluations of Intestinal Barriers for the Zwitterion L-767,679 and Its Carboxyl Ester Prodrug L-775,318. Roles of Efflux and Metabolism
Drug Metab Dispos 1998 26: 520-527. [Abstract] [Full Text] [PDF]  

Stig H. G. Andersson, Anders Lindgren, and Hans Postlind
Biotransformation of Tolterodine, a New Muscarinic Receptor Antagonist, in Mice, Rats, and Dogs
Drug Metab Dispos 1998 26: 528-535. [Abstract] [Full Text] [PDF]  

Bettina A. Hamelin, Asmàa Bouayad, Benoît Drolet, Anne Gravel, and Jacques Turgeon
In Vitro Characterization of Cytochrome P450 2D6 Inhibition by Classic Histamine H1 Receptor Antagonists
Drug Metab Dispos 1998 26: 536-539. [Abstract] [Full Text] [PDF]  

Stefan O. Mueller, Helga Stopper, and Wolfgang Dekant
Biotransformation of the Anthraquinones Emodin and Chrysophanol by Cytochrome P450 Enzymes. Bioactivation to Genotoxic Metabolites
Drug Metab Dispos 1998 26: 540-546. [Abstract] [Full Text] [PDF]  

Mark F. Kearney, James F. Brien, Gerald S. Marks, Hua Lei, and Kanji Nakatsu
Thiol Agents Separate Nitric Oxide Formation from Vasodilation Induced by Glyceryl Trinitrate
Drug Metab Dispos 1998 26: 547-551. [Abstract] [Full Text] [PDF]  

Tatiana Koudriakova, Eugenia Iatsimirskaia, Ilya Utkin, Eric Gangl, Paul Vouros, Elena Storozhuk, Daniela Orza, Julia Marinina, and Nicholas Gerber
Metabolism of the Human Immunodeficiency Virus Protease Inhibitors Indinavir and Ritonavir by Human Intestinal Microsomes and Expressed Cytochrome P4503A4/3A5: Mechanism-Based Inactivation of Cytochrome P4503A by Ritonavir
Drug Metab Dispos 1998 26: 552-561. [Abstract] [Full Text] [PDF]  

Michael Weiss
Analysis of Metabolite Formation Pharmacokinetics after Intravenous and Oral Administration of the Parent Drug Using Inverse Laplace Transformation
Drug Metab Dispos 1998 26: 562-565. [Abstract] [Full Text] [PDF]  

Takanori Hashizume, Masashi Mise, Yoshiaki Terauchi, Luan O, Toshihiko Fujii, Hisashi Miyazaki, and Tadanobu Inaba
N-Dealkylation and Hydroxylation of Ebastine by Human Liver Cytochrome P450
Drug Metab Dispos 1998 26: 566-571. [Abstract] [Full Text] [PDF]  

Susan Rotzinger, Jian Fang, and Glen B. Baker
Trazodone Is Metabolized to m-Chlorophenylpiperazine by CYP3A4 from Human Sources
Drug Metab Dispos 1998 26: 572-575. [Abstract] [Full Text] [PDF]  

Ulrich Busch, Jochen Schmid, Günther Heinzel, Helmut Schmaus, Jürgen Baierl, Claudia Huber, and Willy Roth
Pharmacokinetics of Meloxicam in Animals and The Relevance to Humans
Drug Metab Dispos 1998 26: 576-584. [Abstract] [Full Text] [PDF]  

Hisham A. El-Masri and Christopher J. Portier
Physiologically Based Pharmacokinetics Model of Primidone and Its Metabolites Phenobarbital and Phenylethylmalonamide in Humans, Rats, and Mice
Drug Metab Dispos 1998 26: 585-594. [Abstract] [Full Text] [PDF]  

Hironori Nakura, Tomonori Tateishi, Minoru Watanabe, Masako Asoh, Masami Tanaka, Toshio Kumai, and Shinichi Kobayashi
Effect of Hypoalbuminemia on the Disposition of Theophylline. Comparative Study with Sprague-Dawley Rats and a Mutant Sprague-Dawley Hyperlipidemic Strain with Hypoalbuminemia
Drug Metab Dispos 1998 26: 595-597. [Abstract] [Full Text] [PDF]  

Robert T. Dunn II and Curtis D. Klaassen
Tissue-Specific Expression of Rat Sulfotransferase Messenger RNAs
Drug Metab Dispos 1998 26: 598-604. [Abstract] [Full Text] [PDF]  

Short Communications:

Douglas K. Spracklin and Evan D. Kharasch
Human Halothane Reduction In Vitro by Cytochrome P450 2A6 and 3A4: Identification of Low and High KM Isoforms
Drug Metab Dispos 1998 26: 605-607. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


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