Celsis microsomes mean better data

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October 1999; 27 (10)   [Index by Author]  [Cover Caption]
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Articles:

Barbara J. Ring, Steven A. Wrighton, Susanna L. K. Aldridge, Kristian Hansen, Barbara Haehner, and Lisa A. Shipley
Flavin-Containing Monooxygenase-Mediated N-Oxidation of the M1-Muscarinic Agonist Xanomeline
Drug Metab Dispos 1999 27: 1099-1103. [Abstract] [Full Text] [PDF]  

Johan Rosenborg, Per Larsson, Kerstin Tegnér, and Gösta Hallström
Mass Balance and Metabolism of [3H]Formoterol in Healthy Men after Combined i.v. and Oral Administration-Mimicking Inhalation
Drug Metab Dispos 1999 27: 1104-1116. [Abstract] [Full Text] [PDF]  

Collen M. Masimirembwa, Charlotta Otter, Mikael Berg, Marie Jönsson, Brith Leidvik, Eva Jonsson, Thore Johansson, Assar Bäckman, Anders Edlund, and Tommy B. Andersson
Heterologous Expression and Kinetic Characterization of Human Cytochromes P-450: Validation of a Pharmaceutical Tool for Drug Metabolism Research
Drug Metab Dispos 1999 27: 1117-1122. [Abstract] [Full Text] [PDF]  

Qing-Yu Zhang, Xinxin Ding, Deborah Dunbar, Ling Cao, and Laurence S. Kaminsky
Induction of Rat Small Intestinal Cytochrome P-450 2J4
Drug Metab Dispos 1999 27: 1123-1127. [Abstract] [Full Text] [PDF]  

Jeri S. Roth, Cynthia M. McCully, Frank M. Balis, David G. Poplack, and James A. Kelley
2'-beta -Fluoro-2',3'-dideoxyadenosine, Lodenosine, in Rhesus Monkeys: Plasma and Cerebrospinal Fluid Pharmacokinetics and Urinary Disposition
Drug Metab Dispos 1999 27: 1128-1132. [Abstract] [Full Text] [PDF]  

Susan K. Paulson, Leslie Engel, Beverly Reitz, Suzanne Bolten, Earl G. Burton, Timothy J. Maziasz, Bo Yan, and Grant L. Schoenhard
Evidence for Polymorphism in the Canine Metabolism of the Cyclooxygenase 2 Inhibitor, Celecoxib
Drug Metab Dispos 1999 27: 1133-1142. [Abstract] [Full Text] [PDF]  

T. Ebner, G. Heinzel, A. Prox, K. Beschke, and H. Wachsmuth
Disposition and Chemical Stability of Telmisartan 1-O-Acylglucuronide
Drug Metab Dispos 1999 27: 1143-1149. [Abstract] [Full Text] [PDF]  

Gonzalo J. Diaz, Konstantine W. Skordos, Garold S. Yost, and E. James Squires
Identification of Phase I Metabolites of 3-Methylindole Produced by Pig Liver Microsomes
Drug Metab Dispos 1999 27: 1150-1156. [Abstract] [Full Text] [PDF]  

Joanna D. Moody, James P. Freeman, and Carl E. Cerniglia
Biotransformation of Doxepin by Cunninghamella elegans
Drug Metab Dispos 1999 27: 1157-1164. [Abstract] [Full Text] [PDF]  

Ziqiang Cheng, Anna Radominska-Pandya, and Thomas R. Tephly
Studies on the Substrate Specificity of Human Intestinal UDP-Glucuronosyltransferases 1A8 and 1A10
Drug Metab Dispos 1999 27: 1165-1170. [Abstract] [Full Text] [PDF]  

Graeme B. Scarfe, John C. Lindon, Jeremy K. Nicholson, Brian Wright, Eddie Clayton, and Ian D. Wilson
Investigation of the Quantitative Metabolic Fate and Urinary Excretion of 3-Methyl-4-Trifluoromethylaniline and 3-Methyl-4-Trifluoromethylacetanilide in the Rat
Drug Metab Dispos 1999 27: 1171-1178. [Abstract] [Full Text] [PDF]  

Harumi Takahashi, Toshitaka Kashima, Sosuke Kimura, Noboru Murata, Toshihiro Takaba, Kazunori Iwade, Tomio Abe, Hitoshi Tainaka, Toshio Yasumori, and Hirotoshi Echizen
Pharmacokinetic Interaction between Warfarin and a Uricosuric Agent, Bucolome: Application of In Vitro Approaches to Predicting In Vivo Reduction of (S)-Warfarin Clearance
Drug Metab Dispos 1999 27: 1179-1186. [Abstract] [Full Text] [PDF]  

Jiunn H. Lin, Masato Chiba, I-Wu Chen, Joy A. Nishime, Florencia A. deLuna, Masayo Yamazaki, and Yuh J. Lin
Effect of Dexamethasone on the Intestinal First-Pass Metabolism of Indinavir in Rats: Evidence of Cytochrome P-450 A and p-Glycoprotein Induction
Drug Metab Dispos 1999 27: 1187-1193. [Abstract] [Full Text] [PDF]  

Vinod Ramachandran, Vsevolod E. Kostrubsky, Bernard J. Komoroski, Shimin Zhang, Kenneth Dorko, James E. Esplen, Stephen C. Strom, and Raman Venkataramanan
Troglitazone Increases Cytochrome P-450 3A Protein and Activity in Primary Cultures of Human Hepatocytes
Drug Metab Dispos 1999 27: 1194-1199. [Abstract] [Full Text] [PDF]  

Toshio Chow, Toyoko Hiroi, Susumu Imaoka, Kan Chiba, and Yoshihiko Funae
Isoform-Selective Metabolism of Mianserin by Cytochrome P-450 2D
Drug Metab Dispos 1999 27: 1200-1204. [Abstract] [Full Text] [PDF]  

Petter Balke Jacobsen, Åsmund Larsen, Roozbeh Konarboland, and Tore Skotland
Biotransformation of Nonionic X-Ray Contrast Agents In Vivo and In Vitro
Drug Metab Dispos 1999 27: 1205-1213. [Abstract] [Full Text] [PDF]  

Scott D. Appleton, Marc L. Chretien, Brian E. McLaughlin, Hendrik J. Vreman, David K. Stevenson, James F. Brien, Kanji Nakatsu, Donald H. Maurice, and Gerald S. Marks
Selective Inhibition of Heme Oxygenase, without Inhibition of Nitric Oxide Synthase or Soluble Guanylyl Cyclase, by Metalloporphyrins at Low Concentrations
Drug Metab Dispos 1999 27: 1214-1219. [Abstract] [Full Text] [PDF]  

Mats O. Karlsson, Valeria Molnar, Agneta Freijs, Peter Nygren, Jonas Bergh, and Rolf Larsson
Pharmacokinetic Models for the Saturable Distribution of Paclitaxel
Drug Metab Dispos 1999 27: 1220-1223. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the cover: Metabolic Pathways of the Bronchodilator Formoterol---Applied abbreviations within parentheses. Uncertain biotransformation steps are indicated with dashed lines. F, formoterol. See the article by Rosenberg et al. on page 1104 of this issue.



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