Articles:

William L. Casley, J. Allan Menzies, Larry W. Whitehouse, and Thomas W. Moon

Detection of Quantitative Trait Loci Affecting Caffeine Metabolism by Interval Mapping in a Genome-Wide Scan of C3H/HeJ × APN F₂ Mice
Drug Metab Dispos 1999 27: 1375-1380. [Abstract] [Full Text] [PDF]  

Miki Nakajima, Sumika Nakamura, Shogo Tokudome, Noriaki Shimada, Hiroshi Yamazaki, and Tsuyoshi Yokoi

Azelastine N-Demethylation by Cytochrome P-450 (CYP)3A4, CYP2D6, and CYP1A2 in Human Liver Microsomes: Evaluation of Approach to Predict the Contribution of Multiple CYPs
Drug Metab Dispos 1999 27: 1381-1391. [Abstract] [Full Text] [PDF]  

Masahiko Kawai, Stelvio M. Bandiera, Thomas K. H. Chang, Frederique M. Poulet, Paul M. Vancutsem, and Gail D. Bellward

Modulation of Hepatic CYP2A1, CYP2C11, and CYP3A9 Expression in Adult Rats by Neonatal Administration of Tamoxifen
Drug Metab Dispos 1999 27: 1392-1398. [Abstract] [Full Text] [PDF]  

Peter J. Ferguson, Catherine Currie, and Mark D. Vincent

Enhancement of Platinum-Drug Cytotoxicity in a Human Head and Neck Squamous Cell Carcinoma Line and its Platinum-Resistant Variant by Liposomal Amphotericin B and Phospholipase A2-II
Drug Metab Dispos 1999 27: 1399-1405. [Abstract] [Full Text] [PDF]  

Kenji Matsui, Mannen Mishima, Yasushi Nagai, Teruaki Yuzuriha, and Tsutomu Yoshimura

Absorption, Distribution, Metabolism, and Excretion of Donepezil (Aricept) after a Single Oral Administration to Rat
Drug Metab Dispos 1999 27: 1406-1414. [Abstract] [Full Text] [PDF]  

Pablo Steinberg, Thomas Fischer, Sandra Kiulies, Katja Biefang, Karl-Ludwig Platt, Franz Oesch, Thomas Böttger, Clemens Bulitta, Peter Kempf, and Jan Hengstler

Drug Metabolizing Capacity of Cryopreserved Human, Rat, and Mouse Liver Parenchymal Cells in Suspension
Drug Metab Dispos 1999 27: 1415-1422. [Abstract] [Full Text] [PDF]  

Jennifer Q. Dong, Amy S. Etheridge, and Philip C. Smith

Effect of Selective Phase II Enzyme Inducers on Glucuronidation of Benoxaprofen in Rats
Drug Metab Dispos 1999 27: 1423-1428. [Abstract] [Full Text] [PDF]  

Kaoru Kobayashi, Seiji Abe, Miki Nakajima, Noriaki Shimada, Masayoshi Tani, Kan Chiba, and Toshinori Yamamoto

Role of Human CYP2B6 in S-Mephobarbital N-Demethylation
Drug Metab Dispos 1999 27: 1429-1433. [Abstract] [Full Text] [PDF]  

Paul S. Riska, David P. Joseph, Roger M. Dinallo, Walter C. Davidson, James J. Keirns, and Susan E. Hattox

Biotransformation of Nevirapine, a Non-nucleoside HIV-1 Reverse Transcriptase Inhibitor, in Mice, Rats, Rabbits, Dogs, Monkeys, and Chimpanzees
Drug Metab Dispos 1999 27: 1434-1447. [Abstract] [Full Text] [PDF]  

Omar Ghosheh, Linda P. Dwoskin, Wen-Kui Li, and Peter A. Crooks

Residence Times and Half-Lives of Nicotine Metabolites in Rat Brain after Acute Peripheral Administration of [2'-¹⁴C]Nicotine
Drug Metab Dispos 1999 27: 1448-1455. [Abstract] [Full Text] [PDF]  

Jason S. Halladay, John-Michael Sauer, and I. Glenn Sipes

Metabolism and Disposition of [¹⁴C]1-Nitronaphthalene in Male Sprague-Dawley Rats
Drug Metab Dispos 1999 27: 1456-1465. [Abstract] [Full Text] [PDF]  

John P. Gibbs, Chris A. Liacouras, Robert N. Baldassano, and John T. Slattery

Up-Regulation of Glutathione S-Transferase Activity in Enterocytes of Young Children
Drug Metab Dispos 1999 27: 1466-1469. [Abstract] [Full Text] [PDF]  

Jean-Paul Payan, Dominique Beydon, Benoît Cossec, André Ensminger, Jean-Paul Fabry, and Elisabeth Ferrari

Toxicokinetics of 1,2-Diethylbenzene in Male Sprague-Dawley RatsPart 1: Excretion and Metabolism of [¹⁴C]1,2-Diethylbenzene
Drug Metab Dispos 1999 27: 1470-1478. [Abstract] [Full Text] [PDF]  

Murali Ramanathan

A Method for Estimating Pharmacokinetic Risks of Concentration-Dependent Drug Interactions from Preclinical Data
Drug Metab Dispos 1999 27: 1479-1487. [Abstract] [Full Text] [PDF]  

David A. Erickson, Gary Mather, William F. Trager, Rene H. Levy, and James J. Keirns

Characterization of the In Vitro Biotransformation of the HIV-1 Reverse Transcriptase Inhibitor Nevirapine by Human Hepatic Cytochromes P-450
Drug Metab Dispos 1999 27: 1488-1495. [Abstract] [Full Text] [PDF]  

Raymond J. Bergeron, William R. Weimar, and Jan Wiegand

Pharmacokinetics of Orally Administered Desferrithiocin Analogs in Cebus apella Primates
Drug Metab Dispos 1999 27: 1496-1498. [Abstract] [Full Text] [PDF]  

James M. Mathews and Kristi S. De Costa

Absorption, Metabolism, and Disposition of 1,3-Diphenyl-1-Triazene in Rats and Mice after Oral, i.v., and Dermal Administration
Drug Metab Dispos 1999 27: 1499-1504. [Abstract] [Full Text] [PDF]  

Walter Jäger, Maria Almira Correia, Lester M. Bornheim, Axel Mahnke, Walter G. Hanstein, Linlong Xue, and Leslie Z. Benet

Ethynylestradiol-Mediated Induction of Hepatic CYP3A9 in Female Rats: Implication for Cyclosporine Metabolism
Drug Metab Dispos 1999 27: 1505-1511. [Abstract] [Full Text] [PDF]  

Vinayak P. Hosagrahara, Linda K. Hansen, and Rory P. Remmel

Induction of the Metabolism of Midazolam by Rifampin in Cultured Porcine Hepatocytes: Preliminary Evidence for CYP3A Isoforms in Pigs
Drug Metab Dispos 1999 27: 1512-1518. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Karthik Venkatakrishnan, Lisa L. von Moltke, and David J. Greenblatt

Letter to the Editor: CYP2C9 Is a Principal Low-Affinity Phenacetin O-Deethylase: Fluvoxamine Is Not a Specific CYP1A2 Inhibitor.
Drug Metab Dispos 1999 27: 1519-1520. [Full Text] [PDF]  

Kaoru Kobayashi, Miki Nakajima, Kanako Oshima, Noriaki Shimada, Tsuyoshi Yokoi, and Kan Chiba

Response to Letter to the Editor
Drug Metab Dispos 1999 27: 1521-1522. [Full Text] [PDF]  

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