Celsis microsomes mean better data

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May 1999; 27 (5)   [Index by Author]  [Cover Caption]
       Articles
       Short Communications
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Articles:

H. Ericsson, B. Tholander, J. A. Björkman, M. Nordlander, and C. G. Regårdh
Pharmacokinetics of New Calcium Channel Antagonist Clevidipine in the Rat, Rabbit, and Dog and Pharmacokinetic/Pharmacodynamic Relationship in Anesthetized Dogs
Drug Metab Dispos 1999 27: 558-564. [Abstract] [Full Text] [PDF]  

B. Baune, V. Furlan, A. M. Taburet, and R. Farinotti
Effect of Selected Antimalarial Drugs and Inhibitors of Cytochrome P-450 3A4 on Halofantrine Metabolism by Human Liver Microsomes
Drug Metab Dispos 1999 27: 565-568. [Abstract] [Full Text] [PDF]  

Peter A. Münzel, Stefan Schmohl, Horst Heel, Katharina Kälberer, Barbara S. Bock-Hennig, and Karl Walter Bock
Induction of Human UDP Glucuronosyltransferases (UGT1A6, UGT1A9, and UGT2B7) by t-Butylhydroquinone and 2,3,7,8-Tetrachlorodibenzo-p-Dioxin in Caco-2 Cells
Drug Metab Dispos 1999 27: 569-573. [Abstract] [Full Text] [PDF]  

Siamak C. Khojasteh-Bakht, Weiqiao Chen, Luke L. Koenigs, Raimund M. Peter, and Sidney D. Nelson
Metabolism of (R)-(+)-Pulegone and (R)-(+)-Menthofuran by Human Liver Cytochrome P-450s: Evidence for Formation of a Furan Epoxide
Drug Metab Dispos 1999 27: 574-580. [Abstract] [Full Text] [PDF]  

G. Y. Kwei, R. F. Alvaro, Q. Chen, H. J. Jenkins, C. E. A. C. Hop, C. A. Keohane, V. T. Ly, J. R. Strauss, R. W. Wang, Z. Wang, T. R. Pippert, and D. R. Umbenhauer
Disposition of Ivermectin and Cyclosporin A in CF-1 Mice Deficient in mdr1a P-Glycoprotein
Drug Metab Dispos 1999 27: 581-587. [Abstract] [Full Text] [PDF]  

Dorothy Pless, Jean Noel Gouze, Claire Senay, Regine Herber, Pierre Leroy, Veronique Barberousse, Sylvie Fournel-Gigleux, and Jacques Magdalou
Characterization of the UDP-Glucuronosyltransferases Involved in the Glucuronidation of An Antithrombotic Thioxyloside in Rat and Humans
Drug Metab Dispos 1999 27: 588-595. [Abstract] [Full Text] [PDF]  

Megan A. Gibbs, Kent L. Kunze, William N. Howald, and Kenneth E. Thummel
Effect of Inhibitor Depletion on Inhibitory Potency: Tight Binding Inhibition of CYP3A by Clotrimazole
Drug Metab Dispos 1999 27: 596-599. [Abstract] [Full Text] [PDF]  

Stanislav Yanev, Ute M. Kent, Bozidarka Pandova, and Paul F. Hollenberg
Selective Mechanism-Based Inactivation of Cytochromes P-450 2B1 and P-450 2B6 by a Series of Xanthates
Drug Metab Dispos 1999 27: 600-604. [Abstract] [Full Text] [PDF]  

Anita Hiller, Nghia Nguyen, Christian P. Strassburg, Qing Li, Harald Jainta, Birgit Pechstein, Peter Ruus, Jürgen Engel, Robert H. Tukey, and Thomas Kronbach
Retigabine N-Glucuronidation and Its Potential Role in Enterohepatic Circulation
Drug Metab Dispos 1999 27: 605-612. [Abstract] [Full Text] [PDF]  

Roland Hempel, Hubert Schupke, Patrick J. McNeilly, Kristina Heinecke, Christiane Kronbach, Christian Grunwald, Gottfried Zimmermann, Christian Griesinger, Jürgen Engel, and Thomas Kronbach
Metabolism of Retigabine (D-23129), a Novel Anticonvulsant
Drug Metab Dispos 1999 27: 613-622. [Abstract] [Full Text] [PDF]  

Laurent Placidi, Erika Cretton Scott, Devin Eckoff, Steven Bynon, and Jean-Pierre Sommadossi
Metabolic Drug Interactions between Angiogenic Inhibitor, Tnp-470 and Anticancer Agents in Primary Cultured Hepatocytes and Microsomes
Drug Metab Dispos 1999 27: 623-626. [Abstract] [Full Text] [PDF]  

Andrew Crowe, Armin Bruelisauer, Louise Duerr, Pierrette Guntz, and Michel Lemaire
Absorption and Intestinal Metabolism of SDZ-RAD and Rapamycin in Rats
Drug Metab Dispos 1999 27: 627-632. [Abstract] [Full Text] [PDF]  

Short Communications:

Olga V. Trubetskoy and Peter M. Shaw
A Fluorescent Assay Amenable to Measuring Production of beta -D-Glucuronides Produced from Recombinant UDP-Glycosyl Transferase Enzymes
Drug Metab Dispos 1999 27: 555-557. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the cover: Proposed metabolic pathway of the angiogenic inhibitor TP-470. See the article by Placidi et al. on page 623 in this issue.



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