Articles:

A. Möller, K. Iwasaki, A. Kawamura, Y. Teramura, T. Shiraga, T. Hata, A. Schäfer, and N. A. Undre

The Disposition of ¹⁴C-Labeled Tacrolimus after Intravenous and Oral Administration in Healthy Human Subjects
Drug Metab Dispos 1999 27: 633-636. [Abstract] [Full Text] [PDF]  

Xingrong Liu, Jack P. Chism, Edward L. LeCluyse, Kenneth R. Brouwer, and Kim L.R. Brouwer

Correlation of Biliary Excretion in Sandwich-Cultured Rat Hepatocytes and In Vivo in Rats
Drug Metab Dispos 1999 27: 637-644. [Abstract] [Full Text] [PDF]  

Dung L. Thai, Linda N. Yurasits, George R. Rudolph, and James M. Perel

Comparative Pharmacokinetics and Tissue Distribution of the d-Enantiomers of Para-Substituted Methylphenidate Analogs
Drug Metab Dispos 1999 27: 645-650. [Abstract] [Full Text] [PDF]  

Tomonori Tateishi, Minoru Watanabe, Hironori Nakura, Masami Tanaka, Toshio Kumai, Shigeko Fujimoto Sakata, Nanaya Tamaki, Kenichiro Ogura, Takahito Nishiyama, Tadashi Watabe, and Shinichi Kobayashi

Dihydropyrimidine Dehydrogenase Activity and Fluorouracil Pharmacokinetics with Liver Damage Induced by Bile Duct Ligation in Rats
Drug Metab Dispos 1999 27: 651-654. [Abstract] [Full Text] [PDF]  

Partha Roy, Li J. Yu, Charles L. Crespi, and David J. Waxman

Development of a Substrate-Activity Based Approach To Identify the Major Human Liver P-450 Catalysts of Cyclophosphamide and Ifosfamide Activation Based on cDNA-Expressed Activities and Liver Microsomal P-450 Profiles
Drug Metab Dispos 1999 27: 655-666. [Abstract] [Full Text] [PDF]  

Sang Geon Kim, Min Kyung Cho, Sung Hee Choi, Hye Jung Kim, Mi Kyong Kwak, and Nak Doo Kim

Molecular Basis for Hepatic Detoxifying Enzyme Induction by 2-(Allylthio)pyrazine in Rats in Comparison with Oltipraz: Effects on Prooxidant Production and DNA Degradation
Drug Metab Dispos 1999 27: 667-673. [Abstract] [Full Text] [PDF]  

Caroline M. Henesey, Ginny L. Kellner-Weibel, Joan B. Tarloff, and Peter J. Harvison

Comparative Disposition of the Nephrotoxicant N-(3,5-Dichlorophenyl)Succinimide and the Non-Nephrotoxicant N-(3,5-Difluorophenyl)Succinimide in Fischer 344 Rats
Drug Metab Dispos 1999 27: 674-680. [Abstract] [Full Text] [PDF]  

Shangara S. Dehal and David Kupfer

Cytochrome P-450 3A and 2D6 Catalyze Ortho Hydroxylation of 4-Hydroxytamoxifen and 3-Hydroxytamoxifen (Droloxifene) Yielding Tamoxifen Catechol: Involvement of Catechols in Covalent Binding to Hepatic Proteins
Drug Metab Dispos 1999 27: 681-688. [Abstract] [Full Text] [PDF]  

SaeHeum Song, Hiroshi Suzuki, Ryosei Kawai, and Yuichi Sugiyama

Effect of PSC 833, a P-Glycoprotein Modulator, on the Disposition of Vincristine and Digoxin in Rats
Drug Metab Dispos 1999 27: 689-694. [Abstract] [Full Text] [PDF]  

Angela M. Watson, Samuel M. Poloyac, Georgette Howard, and Robert A. Blouin

Effect of Leptin on Cytochrome P-450, Conjugation, and Antioxidant Enzymes in the ob/ob Mouse
Drug Metab Dispos 1999 27: 695-700. [Abstract] [Full Text] [PDF]  

Kai-Min Chu, Oliver Yoa-Pu Hu, and Shyh-Ming Shieh

Cardiovascular Effect and Simultaneous Pharmacokinetic and Pharmacodynamic Modeling of Pimobendan in Healthy Normal Subjects
Drug Metab Dispos 1999 27: 701-709. [Abstract] [Full Text] [PDF]  

So H. Kim, Won B. Kim, and Myung G. Lee

Pharmacokinetic Changes of a New Carbapenem, , after Intravenous Administration to Spontaneously Hypertensive Rats and Deoxycorticosterone Acetate-Salt-Induced Hypertensive Rats
Drug Metab Dispos 1999 27: 710-716. [Abstract] [Full Text] [PDF]  

Evan D. Kharasch, Douglas C. Hankins, Carole Jubert, Kenneth E. Thummel, and Julie K. Taraday

Lack of Single-Dose Disulfiram Effects on Cytochrome P-450 2C9, 2C19, 2D6, and 3A4 Activities: Evidence for Specificity Toward P-450 2E1
Drug Metab Dispos 1999 27: 717-723. [Abstract] [Full Text] [PDF]  

Naotoshi Yamamura, Kaoru Imura, Hideo Naganuma, and Kenji Nishimura

Panipenem, A Carbapenem Antibiotic, Enhances the Glucuronidation of Intravenously Administered Valproic Acid in Rats
Drug Metab Dispos 1999 27: 724-730. [Abstract] [Full Text] [PDF]  

Peter R. Stout and James A. Ruth

Deposition of [³H]Cocaine, [³H]Nicotine, and [³H]Flunitrazepam in Mouse Hair Melanosomes after Systemic Administration
Drug Metab Dispos 1999 27: 731-735. [Abstract] [Full Text] [PDF]  

P. A. Redondo, A. I. Álvarez, J. L. Garcia, O. M. Larrodé, G. Merino, and J. G. Prieto

Presystemic Metabolism of Albendazole: Experimental Evidence of an Efflux Process of Albendazole Sulfoxide to Intestinal Lumen
Drug Metab Dispos 1999 27: 736-740. [Abstract] [Full Text] [PDF]  

Arthur P. Armstrong and Paul F. Hollenberg

Mechanism-Based Inactivation of Rat Liver Cytochrome 2B1 by 2-Methoxy-5-nitrobenzyl Bromide
Drug Metab Dispos 1999 27: 741-745. [Abstract] [Full Text] [PDF]  

Andreas J. Schwab and K. Sandy Pang

The Multiple Indicator-Dilution Method for the Study of Enzyme Heterogeneity in Liver: Theoretical Basis
Drug Metab Dispos 1999 27: 746-755. [Abstract] [Full Text] [PDF]  

Tarundeep Kakkar, Harold Boxenbaum, and Michael Mayersohn

Estimation of K_i in a Competitive Enzyme-Inhibition Model: Comparisons Among Three Methods of Data Analysis
Drug Metab Dispos 1999 27: 756-762. [Abstract] [Full Text] [PDF]  

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