Articles:

William Kielbasa and Ho-Leung Fung

Pharmacokinetics of a Model Organic Nitrite Inhalant and its Alcohol Metabolite in Rats
Drug Metab Dispos 2000 28: 386-391. [Abstract] [Full Text] [PDF]  

Jill S. Warrington, Richard I. Shader, Lisa L. von Moltke, and David J. Greenblatt

In Vitro Biotransformation of Sildenafil (Viagra): Identification of Human Cytochromes and Potential Drug Interactions
Drug Metab Dispos 2000 28: 392-397. [Abstract] [Full Text] [PDF]  

Cendrine Sevoz, Etienne Benoit, and Thierry Buronfosse

Thioesterification of 2-Arylpropionic Acids by Recombinant Acyl-Coenzyme A Synthetases (ACS1 and ACS2)
Drug Metab Dispos 2000 28: 398-402. [Abstract] [Full Text] [PDF]  

Kameswara R. Kuchimanchi, Chandrasekhar Udata, Thomas P. Johnston, and Ashim K. Mitra

Pharmacokinetics, Biliary Excretion, and Tissue Distribution of Novel Anti-HIV Agents, Cosalane and Dihydrocosalane, in Sprague-Dawley Rats
Drug Metab Dispos 2000 28: 403-408. [Abstract] [Full Text] [PDF]  

Mie Kasahara, Hisashi Suzuki, and Izumi Komiya

Studies on the Cytochrome P450 (CYP)-Mediated Metabolic Properties of Miocamycin: Evaluation of the Possibility of a Metabolic Intermediate Complex Formation with CYP, and Identification of the Human CYP Isoforms
Drug Metab Dispos 2000 28: 409-417. [Abstract] [Full Text] [PDF]  

Jean-Claude Maurizis, Maryse Rapp, Colette Nicolas, Monique Ollier, Michel Verny, and Jean-Claude Madelmont

Disposition in Rats of N-Pyridinium-propyl-cyclam, N-Triethylammonium-propyl-cyclam, and N-[Triethylammonium]-3-propyl-[15]ane-N5, Potential Cartilage Imaging Agents
Drug Metab Dispos 2000 28: 418-422. [Abstract] [Full Text] [PDF]  

John Greg Slatter, Larry J. Schaaf, James P. Sams, Kenneth L. Feenstra, Mark G. Johnson, Paul A. Bombardt, Karen Sue Cathcart, Michael T. Verburg, Laura K. Pearson, Linda D. Compton, Langdon L. Miller, David S. Baker, Caroline V. Pesheck, and Raymond S. Lord, III

Pharmacokinetics, Metabolism, and Excretion of Irinotecan (CPT-11) Following I.V. Infusion of [¹⁴C]CPT-11 in Cancer Patients
Drug Metab Dispos 2000 28: 423-433. [Abstract] [Full Text] [PDF]  

Charles D. Thompson, Thomas A. Miller, Mary T. Barthen, Christine M. Dieckhaus, R. Duane Sofia, and Timothy L. Macdonald

The Synthesis, In Vitro Reactivity, and Evidence for Formation in Humans of 5-Phenyl-1,3-oxazinane-2,4-dione, a Metabolite of Felbamate
Drug Metab Dispos 2000 28: 434-439. [Abstract] [Full Text] [PDF]  

Torsten Kraus, Viuita Uttamsingh, M.W. Anders, and Sabine Wolf

Porcine Kidney Microsomal Cysteine S-Conjugate N-Acetyltransferase-Catalyzed N-Acetylation of Haloalkene-Derived Cysteine S-Conjugates
Drug Metab Dispos 2000 28: 440-445. [Abstract] [Full Text] [PDF]  

Minxia M. He, Trent L. Abraham, Thomas J. Lindsay, Sylvia H. Chay, Boris A. Czeskis, and Lisa A. Shipley

Metabolism and Disposition of Moxonidine in Fischer 344 Rats
Drug Metab Dispos 2000 28: 446-459. [Abstract] [Full Text] [PDF]  

Jiunn H. Lin, I-Wu Chen, Masato Chiba, Joy A. Nishime, and Florencia A. deLuna

Route-Dependent Nonlinear Pharmacokinetics of a Novel HIV Protease Inhibitor: Involvement of Enzyme Inactivation
Drug Metab Dispos 2000 28: 460-466. [Abstract] [Full Text] [PDF]  

Shin-ichi Kanamitsu, Kiyomi Ito, Haruhiro Okuda, Kenichiro Ogura, Tadashi Watabe, Kei Muro, and Yuichi Sugiyama

Prediction of In Vivo Drug-Drug Interactions Based on Mechanism-based Inhibition from In Vitro Data: Inhibition of 5-Fluorouracil Metabolism by (E)-5-(2-Bromovinyl)uracil
Drug Metab Dispos 2000 28: 467-474. [Abstract] [Full Text] [PDF]  

Kanji Komatsu, Kiyomi Ito, Yukiko Nakajima, Shin-ichi Kanamitsu, Susumu Imaoka, Yoshihiko Funae, Carol E. Green, Charles A. Tyson, Noriaki Shimada, and Yuichi Sugiyama

Prediction of in Vivo Drug-Drug Interactions between Tolbutamide and Various Sulfonamides in Humans Based on in Vitro Experiments
Drug Metab Dispos 2000 28: 475-481. [Abstract] [Full Text] [PDF]  

Kiminori Mohri, Yoshihiro Uesawa, and Ken-ichi Sagawa

Effects of Long-Term Grapefruit Juice Ingestion on Nifedipine Pharmacokinetics: Induction of Rat Hepatic P-450 by Grapefruit Juice
Drug Metab Dispos 2000 28: 482-486. [Abstract] [Full Text] [PDF]  

Gladys S. Bayse, Laide A. Jinadu, Kiana L. Shaw, and Kelita L. Wiley

The N-Acetylation of Arsanilic Acid In Vitro by Mammalian Enzymes
Drug Metab Dispos 2000 28: 487-492. [Abstract] [Full Text] [PDF]  

Short Communications:

Jeremy T. Gamble, Harry A. Dailey, and Gerald S. Marks

N-Methylprotoporphyrin Is a More Potent Inhibitor of Recombinant Human Than of Recombinant Chicken Ferrochelatase
Drug Metab Dispos 2000 28: 373-375. [Abstract] [Full Text] [PDF]  

Katherine C. Watt and Alan R. Buckpitt

Species Differences in The Regio- and Stereoselectivity of 1-Nitronaphthalene Metabolism
Drug Metab Dispos 2000 28: 376-378. [Abstract] [Full Text] [PDF]  

Javier G. Blanco, Patricia L. Harrison, William E. Evans, and Mary V. Relling

Human Cytochrome P450 Maximal Activities In Pediatric versus Adult Liver
Drug Metab Dispos 2000 28: 379-382. [Abstract] [Full Text] [PDF]  

Manon Gantenbein, Laurence Attolini, Bernard Bruguerolle, Pierre-Henri Villard, Franck Puyoou, Alain Durand, Bruno Lacarelle, Jean Hardwigsen, and Yves-Patrice Le-Treut

Oxidative Metabolism of Bupivacaine into Pipecolylxylidine in Humans Is Mainly Catalyzed by CYP3A
Drug Metab Dispos 2000 28: 383-385. [Abstract] [Full Text] [PDF]  

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