Articles:

Shu L. Lu, Itsaraet Gosriwatana, Ding Y. Liu, Zu D. Liu, Anthony I. Mallet, and Robert C. Hider

Biliary and Urinary Metabolic Profiles of 1,2-Diethyl-3-hydroxypyridin-4-one (CP94) in the Rat
Drug Metab Dispos 2000 28: 873-879. [Abstract] [Full Text] [PDF]  

Zimeng Yan, John G. Nikelly, Lewis Killmer, Jr., and Joan B. Tarloff

Metabolism of para-Aminophenol by Rat Hepatocytes
Drug Metab Dispos 2000 28: 880-886. [Abstract] [Full Text] [PDF]  

Ken Umehara, Shoji Kudo, Yukihiro Hirao, Seiji Morita, Minoru Uchida, Masaaki Odomi, and Gohachiro Miyamoto

Oxidative Cleavage of the Octyl Side Chain of 1-(3,4-Dichlorobenzyl)-5-Octylbiguanide (OPB-2045) in Rat and Dog Liver Preparations
Drug Metab Dispos 2000 28: 887-894. [Abstract] [Full Text] [PDF]  

Christoph Wandel, Richard B. Kim, F. Peter Guengerich, and Alastair J. J. Wood

Mibefradil Is a P-Glycoprotein Substrate and a Potent Inhibitor of Both P-Glycoprotein and CYP3A In Vitro
Drug Metab Dispos 2000 28: 895-898. [Abstract] [Full Text] [PDF]  

Wensheng Lang, John Mao, Terrence W. Doyle, and Bijan Almassian

Isolation and Identification of Urinary Metabolites of Porfiromycin in Dogs and Humans
Drug Metab Dispos 2000 28: 899-904. [Abstract] [Full Text] [PDF]  

Jarin Chun, Ute M. Kent, Rachel M. Moss, Lawrence M. Sayre, and Paul F. Hollenberg

Mechanism-Based Inactivation of Cytochromes P450 2B1 and P450 2B6 by 2-Phenyl-2-(1-piperidinyl)propane
Drug Metab Dispos 2000 28: 905-911. [Abstract] [Full Text] [PDF]  

Harvey Wong, Sanjeev Kumar, Dan W. Rurak, Eddie Kwan, Frank S. Abbott, and K. Wayne Riggs

Ontogeny of Valproic Acid Disposition and Metabolism: A Developmental Study in Postnatal Lambs and Adult Sheep
Drug Metab Dispos 2000 28: 912-919. [Abstract] [Full Text] [PDF]  

Hiroshi Hasegawa, Takehisa Matsukawa, Yoshihiko Shinohara, and Takao Hashimoto

Assessment of the Metabolic Chiral Inversion of D-Leucine in Rat by Gas Chromatography-Mass Spectrometry Combined with a Stable Isotope Dilution Analysis
Drug Metab Dispos 2000 28: 920-924. [Abstract] [Full Text] [PDF]  

David R. Helton, David W. Osborne, Sharon K. Pierson, Michael H. Buonarati, and Robert A. Bethem

Pharmacokinetic Profiles in Rats After Intravenous, Oral, or Dermal Administration of Dapsone
Drug Metab Dispos 2000 28: 925-929. [Abstract] [Full Text] [PDF]  

Sirinmas Katchamart, David M. Stresser, Shangara S. Dehal, David Kupfer, and David E. Williams

Concurrent Flavin-Containing Monooxygenase Down-Regulation and Cytochrome P-450 Induction by Dietary Indoles in Rat: Implications for Drug-Drug Interaction
Drug Metab Dispos 2000 28: 930-936. [Abstract] [Full Text] [PDF]  

Hirotoshi Echizen, Michika Tanizaki, Jun Tatsuno, Kan Chiba, Teresa Berwick, Masayoshi Tani, Frank J. Gonzalez, and Takashi Ishizaki

Identification of CYP3A4 as the Enzyme Involved in the Mono-N-Dealkylation of Disopyramide Enantiomers in Humans
Drug Metab Dispos 2000 28: 937-944. [Abstract] [Full Text] [PDF]  

Leila Cuttle, Andrew J. Munns, Nicole A. Hogg, Justin R. Scott, Wayne D. Hooper, Ronald G. Dickinson, and Elizabeth M. J. Gillam

Phenytoin Metabolism by Human Cytochrome P450: Involvement of P450 3A and 2C Forms in Secondary Metabolism and Drug-Protein Adduct Formation
Drug Metab Dispos 2000 28: 945-950. [Abstract] [Full Text] [PDF]  

Walter P. Frankmoelle, Julio C. Medina, Bei Shan, Mathew R. Narbut, and Holger Beckmann

Glutathione S-Transferase Metabolism of the Antineoplastic Pentafluorophenylsulfonamide in Tissue Culture and Mice
Drug Metab Dispos 2000 28: 951-958. [Abstract] [Full Text] [PDF]  

Jun-Sheng Wang, Janne T. Backman, Päivi Taavitsainen, Pertti J. Neuvonen, and Kari T. Kivistö

Involvement of CYP1A2 and CYP3A4 in Lidocaine N-Deethylation and 3-Hydroxylation in Humans
Drug Metab Dispos 2000 28: 959-965. [Abstract] [Full Text] [PDF]  

Angela Äbelö, Tommy B. Andersson, Madeleine Antonsson, Anna Knuts Naudot, Inger Skånberg, and Lars Weidolf

Stereoselective Metabolism of Omeprazole by Human Cytochrome P450 Enzymes
Drug Metab Dispos 2000 28: 966-972. [Abstract] [Full Text] [PDF]  

Randy C. Dockens, Kenneth S. Santone, James G. Mitroka, Richard A. Morrison, Mohammed Jemal, Douglas S. Greene, and Rashmi H. Barbhaiya

Disposition of Radiolabeled Ifetroban in Rats, Dogs, Monkeys, and Humans
Drug Metab Dispos 2000 28: 973-980. [Abstract] [Full Text] [PDF]  

Susan M. Lankford, Stephen A. Bai, and Joyce A. Goldstein

Cloning of Canine Cytochrome P450 2E1 cDNA: Identification and Characterization of Two Variant Alleles
Drug Metab Dispos 2000 28: 981-986. [Abstract] [Full Text] [PDF]  

Linh T. Nguyen, Murali Ramanathan, Bianca Weinstock-Guttman, Kiran Dole, Colleen Miller, Margaret Planter, Kara Patrick, Carol Brownscheidle, and Lawrence D. Jacobs

Detection of Cytochrome P450 and Other Drug-Metabolizing Enzyme mRNAs in Peripheral Blood Mononuclear Cells Using DNA Arrays
Drug Metab Dispos 2000 28: 987-993. [Abstract] [Full Text] [PDF]  

Sean Ekins, Gianpaolo Bravi, Shelly Binkley, Jennifer S. Gillespie, Barbara J. Ring, James H. Wikel, and Steven A Wrighton

Three- and Four-Dimensional-Quantitative Structure Activity Relationship (3D/4D-QSAR) Analyses of CYP2C9 Inhibitors
Drug Metab Dispos 2000 28: 994-1002. [Abstract] [Full Text] [PDF]  

Young Mi Kim and Daniel M. Ziegler

Size Limits of Thiocarbamides Accepted as Substrates by Human Flavin-Containing Monooxygenase 1
Drug Metab Dispos 2000 28: 1003-1006. [Abstract] [Full Text] [PDF]  

Short Communications:

Helen R. Winter, Yi Wang, and Jashvant D. Unadkat

CYP2C8/9 Mediate Dapsone N-Hydroxylation at Clinical Concentrations of Dapsone
Drug Metab Dispos 2000 28: 865-868. [Abstract] [Full Text] [PDF]  

Ursula Breyer-Pfaff, Udo Mey, Mitchell D. Green, and Thomas R. Tephly

Comparative N-Glucuronidation Kinetics of Ketotifen and Amitriptyline by Expressed Human UDP-Glucuronosyltransferases and Liver Microsomes
Drug Metab Dispos 2000 28: 869-872. [Abstract] [Full Text] [PDF]  

Errata:

Drug Metab Dispos 2000 28: 1007. [Full Text] [PDF]  

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