Articles:

John G. Lamb and Michael R. Franklin

Early Events in the Induction of Rat Hepatic UDP-Glucuronosyltransferases, Glutathione S-Transferase, and Microsomal Epoxide Hydrolase by 1,7-Phenanthroline: Comparison with Oltipraz, tert-Butyl-4-hydroxyanisole, and tert-Butylhydroquinone
Drug Metab Dispos 2000 28: 1018-1023. [Abstract] [Full Text] [PDF]  

Bao Ting Zhu, Ushma K. Patel, May Xiaoxin Cai, and Allan H. Conney

O-Methylation of Tea Polyphenols Catalyzed by Human Placental Cytosolic Catechol-O-Methyltransferase
Drug Metab Dispos 2000 28: 1024-1030. [Abstract] [Full Text] [PDF]  

Bradley S. Mayhew, David R. Jones, and Stephen D. Hall

An In Vitro Model for Predicting In Vivo Inhibition of Cytochrome P450 3A4 by Metabolic Intermediate Complex Formation
Drug Metab Dispos 2000 28: 1031-1037. [Abstract] [Full Text] [PDF]  

Azher M. Hussain and Ashim K. Mitra

Effect of Aging on Tryptophan Hydroxylase in Rat Brain: Implications on Serotonin Level
Drug Metab Dispos 2000 28: 1038-1042. [Abstract] [Full Text] [PDF]  

Jason S. Ngui, Wei Tang, Ralph A. Stearns, Magang Shou, Randall R. Miller, Yong Zhang, Jiunn H. Lin, and Thomas A. Baillie

Cytochrome P450 3A4-Mediated Interaction of Diclofenac and Quinidine
Drug Metab Dispos 2000 28: 1043-1050. [Abstract] [Full Text] [PDF]  

Hao Chen, Alan G. Fantel, and Mont R. Juchau

Catalysis of the 4-Hydroxylation of Retinoic Acids by Cyp3a7 in Human Fetal Hepatic Tissues
Drug Metab Dispos 2000 28: 1051-1057. [Abstract] [Full Text] [PDF]  

Carla B. Washington, Hugh R. Wiltshire, Martha Man, Tina Moy, Steve R. Harris, Eric Worth, Paul Weigl, Zhenmin Liang, David Hall, Lorraine Marriott, and Terrence F. Blaschke

The Disposition of Saquinavir in Normal and P-glycoprotein Deficient Mice, Rats, and in Cultured Cells
Drug Metab Dispos 2000 28: 1058-1062. [Abstract] [Full Text] [PDF]  

Lynn T. Frame, Shogo Ozawa, Susan A. Nowell, Hsien-Chang Chou, Robert R. DeLongchamp, Daniel R. Doerge, Nicholas P. Lang, and Fred F. Kadlubar

A Simple Colorimetric Assay for Phenotyping the Major Human Thermostable Phenol Sulfotransferase (SULT1A1) Using Platelet Cytosols
Drug Metab Dispos 2000 28: 1063-1068. [Abstract] [Full Text] [PDF]  

R. Scott Obach

Metabolism of Ezlopitant, a Nonpeptidic Substance P Receptor Antagonist, in Liver Microsomes: Enzyme Kinetics, Cytochrome P450 Isoform Identity, and In Vitro-In Vivo Correlation
Drug Metab Dispos 2000 28: 1069-1076. [Abstract] [Full Text] [PDF]  

Thomas Walle, Yoko Otake, Alema Galijatovic, Joseph K. Ritter, and U. Kristina Walle

Induction of UDP-Glucuronosyltransferase UGT1A1 by the Flavonoid Chrysin in the Human Hepatoma Cell Line Hep G2
Drug Metab Dispos 2000 28: 1077-1082. [Abstract] [Full Text] [PDF]  

Rosita J. Rodriguez and Cristobal L. Miranda

Isoform Specificity of N-Deacetyl Ketoconazole by Human and Rabbit Flavin-Containing Monooxygenases
Drug Metab Dispos 2000 28: 1083-1086. [Abstract] [Full Text] [PDF]  

Keishi Oikawa, Takashi Watanabe, and Saburou Higuchi

Comparison of Drug Disposition between Wild-Type and Novel Tissue-Type Plasminogen Activator Pamiteplase in Rats
Drug Metab Dispos 2000 28: 1087-1093. [Abstract] [Full Text] [PDF]  

Tanya Coleman, Ellen F. Spellman, Amin Rostami-Hodjegan, Martin S. Lennard, and Geoffrey T. Tucker

The 1'-Hydroxylation of rac-Bufuralol by Rat Brain Microsomes
Drug Metab Dispos 2000 28: 1094-1099. [Abstract] [Full Text] [PDF]  

I. A. M. de Graaf, D. van der Voort, J. H. F. G. Brits, and H. J. Koster

Increased Post-Thaw Viability and Phase I and II Biotransformation Activity in Cryopreserved Rat Liver Slices after Improvement of a Fast-Freezing Method
Drug Metab Dispos 2000 28: 1100-1106. [Abstract] [Full Text] [PDF]  

Catherine K. Yeung, Dieter H. Lang, Kenneth E. Thummel, and Allan E. Rettie

Immunoquantitation of FMO1 in Human Liver, Kidney, and Intestine
Drug Metab Dispos 2000 28: 1107-1111. [Abstract] [Full Text] [PDF]  

Ayman O. S. El-Kadi, Anne-Marie Bleau, Isabelle Dumont, Hélène Maurice, and Patrick du Souich

Role of Reactive Oxygen Intermediates in the Decrease of Hepatic Cytochrome P450 Activity by Serum of Humans and Rabbits with an Acute Inflammatory Reaction
Drug Metab Dispos 2000 28: 1112-1120. [Abstract] [Full Text] [PDF]  

Jiro Kajita, Takashi Kuwabara, Hiroyuki Kobayashi, and Satoshi Kobayashi

CYP3A4 Is Mainly Responsibile for the Metabolism of a New Vinca Alkaloid, Vinorelbine, in Human Liver Microsomes
Drug Metab Dispos 2000 28: 1121-1127. [Abstract] [Full Text] [PDF]  

Toshiro Niwa, Toshifumi Shiraga, Yasuyuki Mitani, Masato Terakawa, Yoji Tokuma, and Akira Kagayama

Stereoselective Metabolism of Cibenzoline, an Antiarrhythmic Drug, by Human and Rat Liver Microsomes: Possible Involvement of CYP2D and CYP3A
Drug Metab Dispos 2000 28: 1128-1134. [Abstract] [Full Text] [PDF]  

SHORT COMMUNICATION:

Sarvesh C. Vashishtha, Edward M. Hawes, Gordon McKay, and Denis J. McCann

Synthesis and Identification of the Quaternary Ammonium-Linked Glucuronide of 1-Phenylimidazole in Human Liver Microsomes and Investigation of the Human UDP-Glucuronosyltransferases Involved
Drug Metab Dispos 2000 28: 1009-1013. [Abstract] [Full Text] [PDF]  

Michael A. Wynalda, Michael J. Hauer, and Larry C. Wienkers

Oxidation of the Novel Oxazolidinone Antibiotic Linezolid in Human Liver Microsomes
Drug Metab Dispos 2000 28: 1014-1017. [Abstract] [Full Text] [PDF]  

Accelerated Communications:

Mark J. Dresser, Karin M. Gerstin, Andrew T. Gray, Donald D. F. Loo, and Kathleen M. Giacomini

Electrophysiological Analysis of the Substrate Selectivity of a Sodium-Coupled Nucleoside Transporter (rCNT1) Expressed in Xenopus laevis Oocytes
Drug Metab Dispos 2000 28: 1135-1140. [Abstract] [Full Text] [PDF]  

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