Minireview:

Mikael Oscarson

Genetic Polymorphisms in the Cytochrome P450 2A6 (CYP2A6) Gene: Implications for Interindividual Differences in Nicotine Metabolism
Drug Metab Dispos 2001 29: 91-95. [Abstract] [Full Text] [PDF]  

Articles:

James T. Lin, Rashmi Sharma, James J. Grady, and Sanjay Awasthi

A Flow Cell Assay for Evaluation of Whole Cell Drug Efflux Kinetics: Analysis of Paclitaxel Efflux in CCRF-CEM Leukemia Cells Overexpressing P-Glycoprotein
Drug Metab Dispos 2001 29: 103-110. [Abstract] [Full Text] [PDF]  

Martha C. Garcia, Chellappagounder Thangavel, and Bernard H. Shapiro

Epidermal Growth Factor Regulation of Female-Dependent CYP2A1 and CYP2C12 in Primary Rat Hepatocyte Culture
Drug Metab Dispos 2001 29: 111-120. [Abstract] [Full Text] [PDF]  

Matthew G. Soars, Robert J. Riley, Karen A. B. Findlay, Marcus J. Coffey, and Brian Burchell

Evidence for Significant Differences in Microsomal Drug Glucuronidation by Canine and Human Liver and Kidney
Drug Metab Dispos 2001 29: 121-126. [Abstract] [Full Text] [PDF]  

M. Gennett Pike, Dennis C. Mays, David W. Macomber, and James J. Lipsky

Metabolism of a Disulfiram Metabolite, S-Methyl N,N-Diethyldithiocarbamate, by Flavin Monooxygenase in Human Renal Microsomes
Drug Metab Dispos 2001 29: 127-132. [Abstract] [Full Text] [PDF]  

Leah M. Hesse, Karthik Venkatakrishnan, Lisa L. von Moltke, Richard I. Shader, and David J. Greenblatt

CYP3A4 Is the Major CYP Isoform Mediating the in Vitro Hydroxylation and Demethylation of Flunitrazepam
Drug Metab Dispos 2001 29: 133-140. [Abstract] [Full Text] [PDF]  

Judy Easterbrook, Chuang Lu, Yumiko Sakai, and Albert P. Li

Effects of Organic Solvents on the Activities of Cytochrome P450 Isoforms, UDP-Dependent Glucuronyl Transferase, and Phenol Sulfotransferase in Human Hepatocytes
Drug Metab Dispos 2001 29: 141-144. [Abstract] [Full Text] [PDF]  

Ryoko Yumoto, Teruo Murakami, Maki Sanemasa, Reishi Nasu, Junya Nagai, and Mikihisa Takano

Pharmacokinetic Interaction of Cytochrome P450 3A-Related Compounds with Rhodamine 123, a P-Glycoprotein Substrate, in Rats Pretreated with Dexamethasone
Drug Metab Dispos 2001 29: 145-151. [Abstract] [Full Text] [PDF]  

Huy Riem Ha, Laurent Bigler, Martin Binder, Peter Kozlik, Bruno Stieger, Manfred Hesse, Hansruedi R. Altorfer, and Ferenc Follath

Metabolism of Amiodarone (Part I): Identification of a New Hydroxylated Metabolite of Amiodarone
Drug Metab Dispos 2001 29: 152-158. [Abstract] [Full Text] [PDF]  

Deborah A. Nicoll-Griffith, Jose M. Silva, Nathalie Chauret, Stephen Day, Yves Leblanc, Patrick Roy, James A. Yergey, Rakesh Dixit, and Darryl Patrick

Application of Rat Hepatocyte Culture to Predict in Vivo Metabolic Auto-Induction: Studies with DFP, a Cyclooxygenase-2 Inhibitor
Drug Metab Dispos 2001 29: 159-165. [Abstract] [Full Text] [PDF]  

Kristi S. De Costa, Sherry R. Black, Brian F. Thomas, Jason P. Burgess, and James M. Mathews

Metabolism and Disposition of -Methylstyrene in Rats
Drug Metab Dispos 2001 29: 166-171. [Abstract] [Full Text] [PDF]  

Zhen-Hua Xu, Thomas C. Wood, Araba A. Adjei, and Richard M. Weinshilboum

Human 3'-Phosphoadenosine 5'-Phosphosulfate Synthetase: Radiochemical Enzymatic Assay, Biochemical Properties, and Hepatic Variation
Drug Metab Dispos 2001 29: 172-178. [Abstract] [Full Text] [PDF]  

Susan M. Fontaine, Eugene A. Mash, Patricia B. Hoyer, and I. Glenn Sipes

Stereochemical Aspects of Vinylcyclohexene Bioactivation in Rodent Hepatic Microsomes and Purified Human Cytochrome P450 Enzyme Systems
Drug Metab Dispos 2001 29: 179-184. [Abstract] [Full Text] [PDF]  

Hequn Yin, Phi Tran, Gerald E. Greenberg, and Volker Fischer

Methanol Solvent May Cause Increased Apparent Metabolic Instability in in Vitro Assays
Drug Metab Dispos 2001 29: 185-193. [Abstract] [Full Text] [PDF]  

Bing-Bing Yuan, Ruy Tchao, Jeffrey M. Voigt, and Howard D. Colby

Maturational Changes in CYP2D16 Expression and Xenobiotic Metabolism in Adrenal Glands from Male and Female Guinea Pigs
Drug Metab Dispos 2001 29: 194-199. [Abstract] [Full Text] [PDF]  

Mitsuo Miyazawa, Masaki Shindo, and Tsutomu Shimada

Oxidation of 1,8-Cineole, the Monoterpene Cyclic Ether Originated From Eucalyptus Polybractea, by Cytochrome P450 3A Enzymes in Rat and Human Liver Microsomes
Drug Metab Dispos 2001 29: 200-205. [Abstract] [Full Text] [PDF]  

Short Communications:

Amita S. Joshi, Henry J. Pieniaszek, Jr., Everett E. Vokes, Nicholas J. Vogelzang, Anna F. Davidson, Lauren E. Richards, Min F. Chai, Michael Finizio, and Mark J. Ratain

Elimination Pathways of [¹⁴C]Losoxantrone in Four Cancer Patients
Drug Metab Dispos 2001 29: 96-99. [Abstract] [Full Text] [PDF]  

Leah M. Hesse, Lisa L. von Moltke, Richard I. Shader, and David J. Greenblatt

Ritonavir, Efavirenz, and Nelfinavir Inhibit CYP2B6 Activity in Vitro: Potential Drug Interactions with Bupropion
Drug Metab Dispos 2001 29: 100-102. [Abstract] [Full Text] [PDF]  

Errata:

Correction to "Identification of a New Human CYP2A Gene Fragment with Close Linkage to CYP2GP1"
Drug Metab Dispos 2001 29: 206. [Full Text] [PDF]  

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