Articles:

Barbro N. Melgert, Peter Olinga, Betty Weert, Maarten J. H. Slooff, Dirk K. F. Meijer, Klaas Poelstra, and Geny M. M. Groothuis

Cellular Distribution and Handling of Liver-Targeting Preparations in Human Livers Studied by a Liver Lobe Perfusion
Drug Metab Dispos 2001 29: 361-367. [Abstract] [Full Text] [PDF]  

Yuh Lin, Ping Lu, Cuyue Tang, Qin Mei, Grit Sandig, A. David Rodrigues, Thomas H. Rushmore, and Magang Shou

Substrate Inhibition Kinetics for Cytochrome P450-Catalyzed Reactions
Drug Metab Dispos 2001 29: 368-374. [Abstract] [Full Text] [PDF]  

Rasmus W. Mortensen, Olivia Corcoran, Claus Cornett, Ulla G. Sidelmann, John C. Lindon, Jeremy K. Nicholson, and Steen Honoré Hansen

S-Naproxen--1-O-acyl Glucuronide Degradation Kinetic Studies by Stopped-Flow High-Performance Liquid Chromatography-¹H NMR and High-Performance Liquid Chromatography-UV
Drug Metab Dispos 2001 29: 375-380. [Abstract] [Full Text] [PDF]  

Min-Sun Baek, Ji-Yeon Kim, Seung-Woon Myung, Yong Hyeon Yim, Jin-Hyun Jeong, and Dong-Hyun Kim

Metabolism of Dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate (DDB) by Human Liver Microsomes: Characterization of Metabolic Pathways and of Cytochrome P450 Isoforms Involved
Drug Metab Dispos 2001 29: 381-388. [Abstract] [Full Text] [PDF]  

Young Jin Chun, Shi Yong Ryu, Tae Cheon Jeong, and Mie Young Kim

Mechanism-Based Inhibition of Human Cytochrome P450 1A1 by Rhapontigenin
Drug Metab Dispos 2001 29: 389-393. [Abstract] [Full Text] [PDF]  

Yong-Hae Han, Yukio Kato, Yuka Watanabe, Kimio Terao, Yoshinori Asoh, and Yuichi Sugiyama

Carrier-Mediated Hepatobiliary Transport of a Novel Antifolate, N-[4-[(2,4-Diamminopteridine-6-yl)methyl]-3,4-dihydro-2H-1,4-benzothiazin-7-yl]carbonyl-L-Homoglutamic Acid, in Rats
Drug Metab Dispos 2001 29: 394-400. [Abstract] [Full Text] [PDF]  

Terry V. Zenser, Vijaya M. Lakshmi, Fong Fu Hsu, and Bernard B. Davis

Methemoglobin Oxidation of N-Acetylbenzidine to Form a Sulfinamide
Drug Metab Dispos 2001 29: 401-406. [Abstract] [Full Text] [PDF]  

Birgit Hagenauer, Alexandra Salamon, Therese Thalhammer, Olaf Kunert, Ernst Haslinger, Paul Klingler, Adrian M. Senderowicz, Edward A. Sausville, and Walter Jäger

In Vitro Glucuronidation of the Cyclin-Dependent Kinase Inhibitor Flavopiridol by Rat and Human Liver Microsomes: Involvement of UDP-Glucuronosyltransferases 1A1 and 1A9
Drug Metab Dispos 2001 29: 407-414. [Abstract] [Full Text] [PDF]  

Margaret L. Weaver, Barbara A. Orwig, Lolita C. Rodriguez, Elizabeth D. Graham, Jefferson A. Chin, Michael J. Shapiro, James F. McLeod, and James B. Mangold

Pharmacokinetics and Metabolism of Nateglinide in Humans
Drug Metab Dispos 2001 29: 415-421. [Abstract] [Full Text] [PDF]  

P. M. Loadman, D. J. Swaine, M. C. Bibby, K. J. Welham, and L. H. Patterson

A Preclinical Pharmacokinetic Study of the Bioreductive Drug AQ4N
Drug Metab Dispos 2001 29: 422-426. [Abstract] [Full Text] [PDF]  

Hiroshi Yamazaki, Tomoko Komatsu, Kei Takemoto, Mayuko Saeki, Yoshinori Minami, Yasuro Kawaguchi, Noriaki Shimada, Miki Nakajima, and Tsuyoshi Yokoi

Decreases in Phenytoin Hydroxylation Activities Catalyzed by Liver Microsomal Cytochrome P450 Enzymes in Phenytoin-Treated Rats
Drug Metab Dispos 2001 29: 427-434. [Abstract] [Full Text] [PDF]  

J. V. Ramji, N. E. Austin, G. W. Boyle, M. H. Chalker, G. Duncan, A. J. Fairless, F. J. Hollis, D. F. McDonnell, T. J. Musick, and P. C. Shardlow

The Disposition of Gemifloxacin, a New Fluoroquinolone Antibiotic, in Rats and Dogs
Drug Metab Dispos 2001 29: 435-442. [Abstract] [Full Text] [PDF]  

Katsuhiro Yamano, Koujirou Yamamoto, Masataka Katashima, Hajime Kotaki, Sayuri Takedomi, Hirotami Matsuo, Hisakazu Ohtani, Yasufumi Sawada, and Tatsuji Iga

Prediction of Midazolamcyp3a Inhibitors Interaction in the Human Liver from in Vivo/in Vitro Absorption, Distribution, and Metabolism Data
Drug Metab Dispos 2001 29: 443-452. [Abstract] [Full Text] [PDF]  

Raquel F. Reinoso, Brian A. Telfer, Beverley S. Brennan, and Malcolm Rowland

Uptake of Teicoplanin by Isolated Rat Hepatocytes: Comparison with in Vivo Hepatic Distribution
Drug Metab Dispos 2001 29: 453-459. [Abstract] [Full Text] [PDF]  

Tansel Kilicarslan, Robert L. Haining, Allan E. Rettie, Usanda Busto, Rachel F. Tyndale, and Edward M. Sellers

Flunitrazepam Metabolism by Cytochrome P450s 2C19 and 3A4
Drug Metab Dispos 2001 29: 460-465. [Abstract] [Full Text] [PDF]  

Wendell W. Weber and Robert L. Smith

Preface
Drug Metab Dispos 2001 29: 467. [Full Text] [PDF]  

Werner Kalow

Pharmacogenetics in Perspective
Drug Metab Dispos 2001 29: 468-470. [Full Text] [PDF]  

Ellen Buschman and Emil Skamene

From Bcg/Lsh/Ity to Nramp1: Three Decades of Search and Research
Drug Metab Dispos 2001 29: 471-473. [Full Text] [PDF]  

Bruce Beutler and Alexander Poltorak

The Sole Gateway to Endotoxin Response: How Lps Was Identified as Tlr4, and Its Role in Innate Immunity
Drug Metab Dispos 2001 29: 474-478. [Abstract] [Full Text] [PDF]  

Sandrine Marquet and Erwin Schurr

Genetics of Susceptibility to Infectious Diseases: Tuberculosis and Leprosy as Examples
Drug Metab Dispos 2001 29: 479-483. [Full Text] [PDF]  

Alain. J. Dessein, Christophe Chevillard, Sandrine Marquet, Sandrine Henri, Dominique Hillaire, and Helia Dessein

Genetics of Parasitic Infections
Drug Metab Dispos 2001 29: 484-488. [Abstract] [Full Text] [PDF]  

Marta Radel and David Goldman

Pharmacogenetics of Alcohol Response and Alcoholism: The Interplay of Genes and Environmental Factors in Thresholds for Alcoholism
Drug Metab Dispos 2001 29: 489-494. [Abstract] [Full Text] [PDF]  

Ernest Beutler, Vincent Felitti, Terri Gelbart, and Ngoc Ho

Genetics of Iron Storage and Hemochromatosis
Drug Metab Dispos 2001 29: 495-499. [Abstract] [Full Text] [PDF]  

Friedrich C. Luft

Molecular Genetics of Salt-Sensitivity and Hypertension
Drug Metab Dispos 2001 29: 500-504. [Abstract] [Full Text] [PDF]  

John A. Eisman

Pharmacogenetics of the Vitamin D Receptor and Osteoporosis
Drug Metab Dispos 2001 29: 505-512. [Abstract] [Full Text] [PDF]  

Dallas M. Swallow, Mark Poulter, and Edward J. Hollox

Intolerance to Lactose and Other Dietary Sugars
Drug Metab Dispos 2001 29: 513-516. [Abstract] [Full Text] [PDF]  

S. C. Mitchell and R. L. Smith

Trimethylaminuria: The Fish Malodor Syndrome
Drug Metab Dispos 2001 29: 517-521. [Abstract] [Full Text] [PDF]  

Michael W. H. Coughtrie and Laura E. Johnston

Interactions between Dietary Chemicals and Human SulfotransferasesMolecular Mechanisms and Clinical Significance
Drug Metab Dispos 2001 29: 522-528. [Abstract] [Full Text] [PDF]  

Nigel J. Gooderham, Stephen Murray, Anthony M. Lynch, Masoud Yadollahi-Farsani, Kaicun Zhao, Alan R. Boobis, and Donald S. Davies

Food-Derived Heterocyclic Amine Mutagens: Variable Metabolism and Significance to Humans
Drug Metab Dispos 2001 29: 529-534. [Abstract] [Full Text] [PDF]  

Adam Drewnowski, Susan Ahlstrom Henderson, and Anne Barratt-Fornell

Genetic Taste Markers and Food Preferences
Drug Metab Dispos 2001 29: 535-538. [Abstract] [Full Text] [PDF]  

S. C. Mitchell

Food Idiosyncrasies: Beetroot and Asparagus
Drug Metab Dispos 2001 29: 539-543. [Abstract] [Full Text] [PDF]  

P. G. Board, G. Chelvanayagam, L. S. Jermiin, N. Tetlow, H.-F. Tzeng, M. W. Anders, and A. C. Blackburn

Identification of Novel Glutathione Transferases and Polymorphic Variants by Expressed Sequence Tag Database Analysis
Drug Metab Dispos 2001 29: 544-547. [Abstract] [Full Text] [PDF]  

Rachel F. Tyndale and Edward M. Sellers

Variable CYP2A6-Mediated Nicotine Metabolism Alters Smoking Behavior and Risk
Drug Metab Dispos 2001 29: 548-552. [Abstract] [Full Text] [PDF]  

Yan Ru Su and Anil G. Menon

Epithelial Sodium Channels and Hypertension
Drug Metab Dispos 2001 29: 553-556. [Abstract] [Full Text] [PDF]  

Robert P. Erickson and Penelope E. Graves

Genetic Variation in -Adrenergic Receptors and Their Relationship to Susceptibility for Asthma and Therapeutic Response
Drug Metab Dispos 2001 29: 557-561. [Abstract] [Full Text] [PDF]  

D. Gail McCarver

ADH2 and CYP2E1 Genetic Polymorphisms: Risk Factors for Alcohol-Related Birth Defects
Drug Metab Dispos 2001 29: 562-565. [Abstract] [Full Text] [PDF]  

B. N. La Du, S. Billecke, C. Hsu, R. W. Haley, and C. A. Broomfield

Serum Paraoxonase (PON1) Isozymes: The Quantitative Analysis of Isozymes Affecting Individual Sensitivity to Environmental Chemicals
Drug Metab Dispos 2001 29: 566-569. [Abstract] [Full Text] [PDF]  

Magnus Ingelman-Sundberg

Implications of Polymorphic Cytochrome P450-Dependent Drug Metabolism for Drug Development
Drug Metab Dispos 2001 29: 570-573. [Abstract] [Full Text] [PDF]  

Jeffrey A. Towbin, Zhiqing Wang, and Hua Li

Genotype and Severity of Long QT Syndrome
Drug Metab Dispos 2001 29: 574-579. [Abstract] [Full Text] [PDF]  

G. Alvan, L. Bertilsson, M.-L. Dahl, M. Ingelman-Sundberg, and F. Sjöqvist

Moving Toward Genetic Profiling in Patient Care: The Scope and Rationale of Pharmacogenetic/Ecogenetic Investigation
Drug Metab Dispos 2001 29: 580-585. [Full Text] [PDF]  

Maureen T. Cronin, Mylan Pho, Debjani Dutta, Felix Frueh, Leslie Schwarcz, and Thomas Brennan

Utilization of New Technologies in Drug Trials and Discovery
Drug Metab Dispos 2001 29: 586-590. [Abstract] [Full Text] [PDF]  

Michael M. Shi, Michael R. Bleavins, and Felix A. de la Iglesia

Pharmacogenetic Application in Drug Development and Clinical Trials
Drug Metab Dispos 2001 29: 591-595. [Abstract] [Full Text] [PDF]  

Federico Innocenti, Lalitha Iyer, and Mark J. Ratain

Pharmacogenetics of Anticancer Agents: Lessons from Amonafide and Irinotecan
Drug Metab Dispos 2001 29: 596-600. [Abstract] [Full Text] [PDF]  

Richard Weinshilboum

Thiopurine Pharmacogenetics: Clinical and Molecular Studies of Thiopurine Methyltransferase
Drug Metab Dispos 2001 29: 601-605. [Abstract] [Full Text] [PDF]  

D. A. P. Evans, H. L. McLeod, S. Pritchard, M. Tariq, and A. Mobarek

Interethnic Variability in Human Drug Responses
Drug Metab Dispos 2001 29: 606-610. [Abstract] [Full Text] [PDF]  

Gilbert S. Omenn

Prospects for Pharmacogenetics and Ecogenetics in the New Millennium
Drug Metab Dispos 2001 29: 611-614. [Abstract] [Full Text] [PDF]  

Errata:

Correction to "Human 3'-Phosphoadenosine 5'-Phosphosulfate Synthetase: Radiochemical Enzymatic Assay, Biochemical Properties, and Hepatic Variation"
Drug Metab Dispos 2001 29: 466. [Full Text] [PDF]  

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