Noab BioDiscoveries - Shaping Drug Discovery

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Other Issues:
August 2001; 29 (8)   [Index by Author]  [Cover Caption]
       Editorial
       Articles
       Errata
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Editorial:

James R. Halpert

Drug Metab Dispos 2001 29: 1073. [Full Text] [PDF]  

Articles:

Scott W. Allen, Lisa Mueller, Susanne N. Williams, Linda C. Quattrochi, and Judy Raucy
The Use of a High-Volume Screening Procedure to Assess the Effects of Dietary Flavonoids on Human CYP1A1 Expression
Drug Metab Dispos 2001 29: 1074-1079. [Abstract] [Full Text] [PDF]  

Er-jia Wang, Christopher N. Casciano, Robert P. Clement, and William W. Johnson
Evaluation of the Interaction of Loratadine and desloratadine with P-glycoprotein
Drug Metab Dispos 2001 29: 1080-1083. [Abstract] [Full Text] [PDF]  

Hiroki Inoue, Hiroshi Yokota, Tsunehisa Makino, Akira Yuasa, and Seiyu Kato
Bisphenol A Glucuronide, a Major Metabolite in Rat Bile after Liver Perfusion
Drug Metab Dispos 2001 29: 1084-1087. [Abstract] [Full Text] [PDF]  

Shashi K. Ramaiah, Udayan Apte, and Harihara M. Mehendale
Cytochrome P4502E1 Induction Increases Thioacetamide Liver Injury in Diet-Restricted Rats
Drug Metab Dispos 2001 29: 1088-1095. [Abstract] [Full Text] [PDF]  

Leena Luukkanen, Jouni Mikkola, Tarja Forsman, Päivi Taavitsainen, Jyrki Taskinen, and Eivor Elovaara
Glucuronidation of 1-Hydroxypyrene by Human Liver Microsomes and Human UDP-Glucuronosyltransferases UGT1A6, UGT1A7, and UGT1A9: Development of a High-Sensitivity Glucuronidation Assay for Human Tissue
Drug Metab Dispos 2001 29: 1096-1101. [Abstract] [Full Text] [PDF]  

Lisa L. von Moltke, David J. Greenblatt, Gina M. Giancarlo, Brian W. Granda, Jerold S. Harmatz, and Richard I. Shader
Escitalopram (S-Citalopram) and Its Metabolites in Vitro: Cytochromes Mediating Biotransformation, Inhibitory Effects, and Comparison to R-Citalopram
Drug Metab Dispos 2001 29: 1102-1109. [Abstract] [Full Text] [PDF]  

Miki Nakajima, Ryoko Yoshida, Noriaki Shimada, Hiroshi Yamazaki, and Tsuyoshi Yokoi
Inhibition and Inactivation of Human Cytochrome P450 Isoforms by Phenethyl Isothiocyanate
Drug Metab Dispos 2001 29: 1110-1113. [Abstract] [Full Text] [PDF]  

Alana L. Upthagrove and Wendel L. Nelson
Carbinolamines, Imines, and Oxazolidines from Fluorinated Propranolol Analogs. 19F NMR and Mass Spectral Characterization and Evidence for Formation as Intermediates in Cytochrome P450-Catalyzed N-Dealkylation
Drug Metab Dispos 2001 29: 1114-1122. [Abstract] [Full Text] [PDF]  

Stephanie R. Faucette, Roy L. Hawke, Stacy S. Shord, Edward L. Lecluyse, and Celeste M. Lindley
Evaluation of the Contribution of Cytochrome P450 3A4 to Human Liver Microsomal Bupropion Hydroxylation
Drug Metab Dispos 2001 29: 1123-1129. [Abstract] [Full Text] [PDF]  

Zhengbo Duanmu, Thomas A. Kocarek, and Melissa Runge-Morris
Transcriptional Regulation of Rat Hepatic Aryl Sulfotransferase (SULT1A1) Gene Expression by Glucocorticoids
Drug Metab Dispos 2001 29: 1130-1135. [Abstract] [Full Text] [PDF]  

J. G. Slatter, D. J. Stalker, K. L. Feenstra, I. R. Welshman, J. B. Bruss, J. P. Sams, M. G. Johnson, P. E. Sanders, M. J. Hauer, P. E. Fagerness, R. P. Stryd, G. W. Peng, and E. M. Shobe
Pharmacokinetics, Metabolism, and Excretion of Linezolid following an Oral Dose of [14C]Linezolid to Healthy Human Subjects
Drug Metab Dispos 2001 29: 1136-1145. [Abstract] [Full Text] [PDF]  

Vangala Subrahmanyam, Anthony B. Renwick, David G. Walters, Philip J. Young, Roger J. Price, Alfred P. Tonelli, and Brian G. Lake
Identification of Cytochrome P-450 Isoforms Responsible for cis-Tramadol Metabolism in Human Liver Microsomes
Drug Metab Dispos 2001 29: 1146-1155. [Abstract] [Full Text] [PDF]  

L. E. Dyck and B. A. Davis
Inhibition of Rat Liver Microsomal CYP1A2 and CYP2B1 Activity by N-(2-Heptyl)-N-methyl-propargylamine and by N-(2-Heptyl)-propargylamine
Drug Metab Dispos 2001 29: 1156-1161. [Abstract] [Full Text] [PDF]  

Mehran F. Moghaddam, Alethia Brown, Boiana O. Budevska, Zamas Lam, and William G. Payne
Biotransformation, Excretion Kinetics, and Tissue Distribution of an N-Pyrrolo[1,2-c]imidazolylphenyl Sulfonamide Herbicide in Rats
Drug Metab Dispos 2001 29: 1162-1170. [Abstract] [Full Text] [PDF]  

Errata:

Correction to "Dapsone Activation of CYP2C9-Mediated Metabolism: Evidence for Activation of Multiple Substrates and a Two-Site Model"
Drug Metab Dispos 2001 29: 1171. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the cover: Metabolism of pyrene in humans. See the article by Luukkanen et al. on page 1096 of this issue.



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