Articles:

Jeffrey P. Jones, Michael Mysinger, and Kenneth Ray Korzekwa

Computational Models for Cytochrome P450: A Predictive Electronic Model for Aromatic Oxidation and Hydrogen Atom Abstraction
Drug Metab Dispos 2002 30: 7-12. [Abstract] [Full Text] [PDF]  

George Hill, Tomas Cihlar, Charles Oo, Edmund S. Ho, Ken Prior, Hugh Wiltshire, Jo Barrett, Baulian Liu, and Penny Ward

The Anti-Influenza Drug Oseltamivir Exhibits Low Potential to Induce Pharmacokinetic Drug Interactions via Renal SecretionCorrelation of in Vivo and in Vitro Studies
Drug Metab Dispos 2002 30: 13-19. [Abstract] [Full Text] [PDF]  

Ali Asghar, J. Christopher Gorski, Barbara Haehner-Daniels, and Stephen D. Hall

Induction of Multidrug Resistance-1 and Cytochrome P450 mRNAs in Human Mononuclear Cells by Rifampin
Drug Metab Dispos 2002 30: 20-26. [Abstract] [Full Text] [PDF]  

Jason T. Johnson, Edward L. Mattiuz, Sylvia H. Chay, Jennifer L. Herman, William J. Wheeler, Kelem Kassahun, Steven P. Swanson, and Diane L. Phillips

The Disposition, Metabolism, and Pharmacokinetics of a Selective Metabotropic Glutamate Receptor Agonist in Rats and Dogs
Drug Metab Dispos 2002 30: 27-33. [Abstract] [Full Text] [PDF]  

Sharon K. Krueger, Sarah R. Martin, Mei-Fei Yueh, Clifford B. Pereira, and David E. Williams

Identification of Active Flavin-Containing Monooxygenase Isoform 2 in Human Lung and Characterization of Expressed Protein
Drug Metab Dispos 2002 30: 34-41. [Abstract] [Full Text] [PDF]  

Tara E. Nicholson and Kenneth W. Renton

The Role of Cytokines in the Depression of CYP1A Activity Using Cultured Astrocytes as an in Vitro Model of Inflammation in the Central Nervous System
Drug Metab Dispos 2002 30: 42-46. [Abstract] [Full Text] [PDF]  

Mehran F. Moghaddam, Matthew S. Bogdanffy, Alethia Brown, Kim Ford, and Lamaat Shalaby

Plasma Pharmacokinetics and Tissue Distribution of a N-Pyrrolo- [1,2-c]Imidazolylphenyl Sulfonamide in Rats
Drug Metab Dispos 2002 30: 47-54. [Abstract] [Full Text] [PDF]  

Mark P. Grillo and Leslie Z. Benet

Studies on the Reactivity of Clofibryl-S-Acyl-CoA Thioester with Glutathione in Vitro
Drug Metab Dispos 2002 30: 55-62. [Abstract] [Full Text] [PDF]  

Masanori Kuroha, Akinori Azumano, Yoji Kuze, Minoru Shimoda, and Eiichi Kokue

Effect of Multiple Dosing of Ketoconazole on Pharmacokinetics of Midazolam, a Cytochrome P-450 3A Substrate in Beagle Dogs
Drug Metab Dispos 2002 30: 63-68. [Abstract] [Full Text] [PDF]  

Rui-Sheng Wang, Tamie Nakajima, Toshihiro Kawamoto, and Takeshi Honma

Effects of Aldehyde Dehydrogenase-2 Genetic Polymorphisms on Metabolism of Structurally Different Aldehydes in Human Liver
Drug Metab Dispos 2002 30: 69-73. [Abstract] [Full Text] [PDF]  

Fatih M. Uckun, Jason Thoen, Hao Chen, Elise Sudbeck, Chen Mao, Ravi Malaviya, Xing-Ping Liu, and Chun-Lin Chen

CYP1A-Mediated Metabolism of the Janus Kinase-3 Inhibitor 4-(4'-Hydroxyphenyl)-amino-6,7-dimethoxyquinazoline: Structural Basis for Inactivation by Regioselective O-Demethylation
Drug Metab Dispos 2002 30: 74-85. [Abstract] [Full Text] [PDF]  

Qinmi Wang and James R. Halpert

Combined Three-Dimensional Quantitative Structure-Activity Relationship Analysis of Cytochrome P450 2B6 Substrates and Protein Homology Modeling
Drug Metab Dispos 2002 30: 86-95. [Abstract] [Full Text] [PDF]  

Accelerated Communication:

Sean Ekins and Jon A. Erickson

A Pharmacophore for Human Pregnane X Receptor Ligands
Drug Metab Dispos 2002 30: 96-99. [Abstract] [Full Text] [PDF]  

Short Communications:

Espen Molden, Anders Åsberg, and Hege Christensen

Desacetyl-Diltiazem Displays Severalfold Higher Affinity to CYP2D6 Compared with CYP3A4
Drug Metab Dispos 2002 30: 1-3. [Abstract] [Full Text] [PDF]  

Tsutomu Nakamura, Toshiyuki Sakaeda, Nobuko Ohmoto, Takao Tamura, Nobuo Aoyama, Toshiro Shirakawa, Takashi Kamigaki, Takeshi Nakamura, Ke Ih Kim, Soo Ryang Kim, Yoshikazu Kuroda, Masafumi Matsuo, Masato Kasuga, and Katsuhiko Okumura

Real-Time Quantitative Polymerase Chain Reaction for MDR1, MRP1, MRP2, and CYP3A-mRNA Levels in Caco-2 Cell Lines, Human Duodenal Enterocytes, Normal Colorectal Tissues, and Colorectal Adenocarcinomas
Drug Metab Dispos 2002 30: 4-6. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Pavel Anzenbacher, Eva Anzenbacherová, Roman Zuber, Pavel Soucek, F. Peter Guengerich, Michael J. Myers, Dorothy E. Farrell, Karyn D. Howard, and Joseph C. Kawalek

Pig and Minipig Cytochromes P450
Drug Metab Dispos 2002 30: 100-102. [Full Text] [PDF]  

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