Articles:

Ken-ichi Nezasa, Kazutaka Higaki, Tadahiko Matsumura, Kazuhiro Inazawa, Hiroshi Hasegawa, Masayuki Nakano, and Masahiro Koike

Liver-Specific Distribution of Rosuvastatin in Rats: Comparison with Pravastatin and Simvastatin
Drug Metab Dispos 2002 30: 1158-1163. [Abstract] [Full Text] [PDF]  

Eric G. Solon, Suresh K. Balani, Gang Luo, Tian J. Yang, Paula J. Haines, Lifei Wang, Tonya Demond, Sharon Diamond, David D. Christ, Liang-Shang Gan, and Frank W. Lee

Interaction of Ritonavir on Tissue Distribution of a [¹⁴C]L-Valinamide, a Potent Human Immunodeficiency Virus-1 Protease Inhibitor, in Rats Using Quantitative Whole-Body Autoradiography
Drug Metab Dispos 2002 30: 1164-1169. [Abstract] [Full Text] [PDF]  

Robin E. Pearce, Gangadhara R. Vakkalagadda, and J. Steven Leeder

Pathways of Carbamazepine Bioactivation in Vitro I. Characterization of Human Cytochromes P450 Responsible for the Formation of 2- and 3-Hydroxylated Metabolites
Drug Metab Dispos 2002 30: 1170-1179. [Abstract] [Full Text] [PDF]  

J. J. Pritchett, R. K. Kuester, and I. G. Sipes

Metabolism of Bisphenol A in Primary Cultured Hepatocytes from Mice, Rats, and Humans
Drug Metab Dispos 2002 30: 1180-1185. [Abstract] [Full Text] [PDF]  

Laura Romero, Marnie A. Higgins, James Gilmore, Kim Boudreau, Ann Maslen, Heather J. Barker, and Gordon M. Kirby

Down-Regulation of Alpha Class Glutathione S-Transferase by Interleukin-1 in Human Intestinal Epithelial Cells (Caco-2) in Culture
Drug Metab Dispos 2002 30: 1186-1193. [Abstract] [Full Text] [PDF]  

J. Matthew Hutzler, Dhanashri Kolwankar, Matthew A. Hummel, and Timothy S. Tracy

Activation of CYP2C9-Mediated Metabolism by a Series of Dapsone Analogs: Kinetics and Structural Requirements
Drug Metab Dispos 2002 30: 1194-1200. [Abstract] [Full Text] [PDF]  

Tomoko Shiraishi, Masakiyo Hosokawa, Kaoru Kobayashi, Hitoshi Tainaka, Yoshiyuki Yamaura, Miwo Taguchi, and Kan Chiba

Effects of G169R and P34S Substitutions Produced by Mutations of CYP2D6*14 on the Functional Properties of CYP2D6 Expressed in V79 Cells
Drug Metab Dispos 2002 30: 1201-1205. [Abstract] [Full Text] [PDF]  

Richard A. Graham, April Downey, Dan Mudra, Linda Krueger, Kathy Carroll, Christopher Chengelis, Ajay Madan, and Andrew Parkinson

In Vivo and in Vitro Induction of Cytochrome P450 Enzymes in Beagle Dogs
Drug Metab Dispos 2002 30: 1206-1213. [Abstract] [Full Text] [PDF]  

Hee Han, Sang-Geon Kim, Myung-Gull Lee, Chang-Koo Shim, and Suk-Jae Chung

Mechanism of the Reduced Elimination Clearance of Benzylpenicillin from Cerebrospinal Fluid in Rats with Intracisternal Administration of Lipopolysaccharide
Drug Metab Dispos 2002 30: 1214-1220. [Abstract] [Full Text] [PDF]  

Franck Desmoulin, Véronique Gilard, Myriam Malet-Martino, and Robert Martino

Metabolism of Capecitabine, an Oral Fluorouracil Prodrug: ¹⁹F NMR Studies in Animal Models and Human Urine
Drug Metab Dispos 2002 30: 1221-1229. [Abstract] [Full Text] [PDF]  

Q. A. McKellar, C. Gokbulut, K. Muzandu, and H. Benchaoui

Fenbendazole Pharmacokinetics, Metabolism, and Potentiation in Horses
Drug Metab Dispos 2002 30: 1230-1239. [Abstract] [Full Text] [PDF]  

Shigeki Matsumoto, Tomoe Hirama, Tsutomu Matsubara, Kiyoshi Nagata, and Yasushi Yamazoe

Involvement of CYP2J2 on the Intestinal First-Pass Metabolism of Antihistamine Drug, Astemizole
Drug Metab Dispos 2002 30: 1240-1245. [Abstract] [Full Text] [PDF]  

Yan Cai, Nathan D. Anavy, and H-H. Sherry Chow

Contribution of Presystemic Hepatic Extraction to the Low Oral Bioavailability of Green Tea Catechins in Rats
Drug Metab Dispos 2002 30: 1246-1249. [Abstract] [Full Text] [PDF]  

Miki Nakajima, Nozomi Sakata, Noriko Ohashi, Toshiyuki Kume, and Tsuyoshi Yokoi

Involvement of Multiple UDP-glucuronosyltransferase 1A Isoforms in Glucuronidation of 5-(4'-hydroxyphenyl)-5-phenylhydantoin in Human Liver Microsomes
Drug Metab Dispos 2002 30: 1250-1256. [Abstract] [Full Text] [PDF]  

Michael H. Court, Su X. Duan, Chantal Guillemette, Kim Journault, Soundararajan Krishnaswamy, Lisa L. von Moltke, and David J. Greenblatt

Stereoselective Conjugation of Oxazepam by Human UDP-Glucuronosyltransferases (UGTs): S-Oxazepam Is Glucuronidated by UGT2B15, While R-Oxazepam Is Glucuronidated by UGT2B7 and UGT1A9
Drug Metab Dispos 2002 30: 1257-1265. [Abstract] [Full Text] [PDF]  

J. Andrew Williams, Barbara J. Ring, Varon E. Cantrell, Kristina Campanale, David R. Jones, Stephen D. Hall, and Steven A. Wrighton

Differential Modulation of UDP-Glucuronosyltransferase 1A1 (UGT1A1)-Catalyzed Estradiol-3-glucuronidation by the Addition of UGT1A1 Substrates and Other Compounds to Human Liver Microsomes
Drug Metab Dispos 2002 30: 1266-1273. [Abstract] [Full Text] [PDF]  

Joanna D. Moody, James P. Freeman, Peter P. Fu, and Carl E. Cerniglia

Biotransformation of Mirtazapine by Cunninghamella Elegans
Drug Metab Dispos 2002 30: 1274-1279. [Abstract] [Full Text] [PDF]  

Thomayant Prueksaritanont, Cuyue Tang, Yue Qiu, Lillian Mu, Raju Subramanian, and Jiunn H. Lin

Effects of Fibrates on Metabolism of Statins in Human Hepatocytes
Drug Metab Dispos 2002 30: 1280-1287. [Abstract] [Full Text] [PDF]  

Jean-Marie Pereillo, Mohamed Maftouh, Alain Andrieu, Marie-Francoise Uzabiaga, Olivier Fedeli, Pierre Savi, Marc Pascal, Jean-Marc Herbert, Jean-Pierre Maffrand, and Claudine Picard

Structure and Stereochemistry of the Active Metabolite of Clopidogrel
Drug Metab Dispos 2002 30: 1288-1295. [Abstract] [Full Text] [PDF]  

Short Communications:

Bruno Bournique and Audrey Lemarié

Docetaxel (Taxotere) Is Not Metabolized by Recombinant Human CYP1B1 in Vitro, but Acts as an Effector of This Isozyme.
Drug Metab Dispos 2002 30: 1149-1152. [Abstract] [Full Text] [PDF]  

James M. Mathews, Amy S. Etheridge, and Sherry R. Black

Inhibition of Human Cytochrome P450 Activities by Kava Extract and Kavalactones
Drug Metab Dispos 2002 30: 1153-1157. [Abstract] [Full Text] [PDF]  

Erratum:

Correction to "The Multiple Indicator-Dilution Method for the Study of Enzyme Heterogeneity in Liver: Theoretical Basis"
Drug Metab Dispos 2002 30: 1296. [Full Text] [PDF]  

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