Articles:

Hisashi Suzuki, M. Byron Kneller, Robert L. Haining, William F. Trager, and Allan E. Rettie

(+)-N-3-Benzyl-Nirvanol and ()-N-3-Benzyl-Phenobarbital: New Potent and Selective in Vitro Inhibitors of CYP2C19
Drug Metab Dispos 2002 30: 235-239. [Abstract] [Full Text] [PDF]  

Nichole R. Vansell and Curtis D. Klaassen

Increase in Rat Liver UDP-Glucuronosyltransferase mRNA by Microsomal Enzyme Inducers that Enhance Thyroid Hormone Glucuronidation
Drug Metab Dispos 2002 30: 240-246. [Abstract] [Full Text] [PDF]  

Gwyn Pakenham, Jozsef Lango, Michael Buonarati, Dexter Morin, and Alan Buckpitt

Urinary Naphthalene Mercapturates as Biomarkers of Exposure and Stereoselectivity of Naphthalene Epoxidation
Drug Metab Dispos 2002 30: 247-253. [Abstract] [Full Text] [PDF]  

Chyan E. Lau and Lei Sun

The Pharmacokinetic Determinants of the Frequency and Pattern of Intravenous Cocaine Self-administration in Rats by Pharmacokinetic Modeling
Drug Metab Dispos 2002 30: 254-261. [Abstract] [Full Text] [PDF]  

David C. Spink, Barbara H. Katz, Mirza M. Hussain, Barbara C. Spink, Susan J. Wu, Ning Liu, Ronald Pause, and Laurence S. Kaminsky

Induction of CYP1A1 and CYP1B1 in T-47D Human Breast Cancer Cells by Benzo[a]pyrene Is Diminished by Arsenite
Drug Metab Dispos 2002 30: 262-269. [Abstract] [Full Text] [PDF]  

Michael B. Fisher, David Jackson, Andreas Kaerner, Steven A. Wrighton, and Anthony G. Borel

Characterization by Liquid Chromatography-Nuclear Magnetic Resonance Spectroscopy and Liquid Chromatography-Mass Spectrometry of Two Coupled Oxidative-Conjugative Metabolic Pathways for 7-Ethoxycoumarin in Human Liver Microsomes Treated with Alamethicin
Drug Metab Dispos 2002 30: 270-275. [Abstract] [Full Text] [PDF]  

Ivan Nestorov, Ivelina Gueorguieva, Hannah M. Jones, Brian Houston, and Malcolm Rowland

Incorporating Measures of Variability and Uncertainty into the Prediction of in Vivo Hepatic Clearance from in Vitro Data
Drug Metab Dispos 2002 30: 276-282. [Abstract] [Full Text] [PDF]  

Grace L. Guo, David R. Johnson, and Curtis D. Klaassen

Postnatal Expression and Induction by Pregnenolone-16-Carbonitrile of the Organic Anion-Transporting Polypeptide 2 in Rat Liver
Drug Metab Dispos 2002 30: 283-288. [Abstract] [Full Text] [PDF]  

Khawja A. Usmani, Randy L. Rose, Joyce A. Goldstein, Wesley G. Taylor, Alan A. Brimfield, and Ernest Hodgson

In Vitro Human Metabolism and Interactions of Repellent N,N-Diethyl-m-Toluamide
Drug Metab Dispos 2002 30: 289-294. [Abstract] [Full Text] [PDF]  

Sanna Kaivosaari, Jarmo S. Salonen, and Jyrki Taskinen

N-Glucuronidation of Some 4-Arylalkyl-1H-Imidazoles by Rat, Dog, and Human Liver Microsomes
Drug Metab Dispos 2002 30: 295-300. [Abstract] [Full Text] [PDF]  

Yujiro Morioka, Makiko Otsu, Shinsaku Naito, and Teruko Imai

Phosphonate O-Deethylation of [4-(4-Bromo-2-Cyano-Phenylcarbamoyl) Benzyl]-Phosphonic Acid Diethyl Ester, a Lipoprotein Lipase-Promoting Agent, Catalyzed by Cytochrome P450 2C8 and 3A4 in Human Liver Microsomes
Drug Metab Dispos 2002 30: 301-306. [Abstract] [Full Text] [PDF]  

Bert Haenen, Cathy Rompelberg, Klaas van Twillert, Martin Hamzink, Jan Dormans, and Jan van Eijkeren

Utility of Rat Liver Slices to Estimate Hepatic Clearance for Application in Physiologically Based Pharmacokinetic Modeling: A Study with Tolbutamide, a Compound with Low Extraction Efficiency
Drug Metab Dispos 2002 30: 307-313. [Abstract] [Full Text] [PDF]  

Wenjiang Zhang, Yamini Ramamoorthy, Tansel Kilicarslan, Helma Nolte, Rachel F. Tyndale, and Edward M. Sellers

Inhibition of Cytochromes P450 by Antifungal Imidazole Derivatives
Drug Metab Dispos 2002 30: 314-318. [Abstract] [Full Text] [PDF]  

Barbara J. Ring, Jennifer S. Gillespie, James A. Eckstein, and Steven A. Wrighton

Identification of the Human Cytochromes P450 Responsible for Atomoxetine Metabolism
Drug Metab Dispos 2002 30: 319-323. [Abstract] [Full Text] [PDF]  

Fay K. Kessler, Marissa R. Kessler, Diana J. Auyeung, and Joseph K. Ritter

Glucuronidation of Acetaminophen Catalyzed by Multiple Rat Phenol UDP-Glucuronosyltransferases
Drug Metab Dispos 2002 30: 324-330. [Abstract] [Full Text] [PDF]  

Xiangming Guan, Brianna N. Hoffman, Douglas C. McFarland, Kysa K. Gilkerson, Chandradhar Dwivedi, Angela K. Erickson, Scott Bebensee, and Jill Pellegrini

Glutathione and Mercapturic Acid Conjugates of Sulofenur and Their Activity against a Human Colon Cancer Cell Line
Drug Metab Dispos 2002 30: 331-335. [Abstract] [Full Text] [PDF]  

Z. Desta, G. M. Wu, A. M. Morocho, and D. A. Flockhart

The Gastroprokinetic and Antiemetic Drug Metoclopramide Is a Substrate and Inhibitor of Cytochrome P450 2D6
Drug Metab Dispos 2002 30: 336-343. [Abstract] [Full Text] [PDF]  

Hui Zheng, Chun Jiang, Ming H. Chiu, Joseph M. Covey, and Kenneth K. Chan

Chiral Pharmacokinetics and Inversion of Enantiomers of a New Quinoxaline Topoisomerase II Poison in the Rat
Drug Metab Dispos 2002 30: 344-348. [Abstract] [Full Text] [PDF]  

Yune-Fang Ueng, Woan-Ching Jan, Lie-Chwen Lin, Ta-Liang Chen, F. Peter Guengerich, and Chieh-Fu Chen

The Alkaloid Rutaecarpine Is a Selective Inhibitor of Cytochrome P450 1A in Mouse and Human Liver Microsomes
Drug Metab Dispos 2002 30: 349-353. [Abstract] [Full Text] [PDF]  

Short Communications:

Raju Subramanian, Xiaojun Fang, and Thomayant Prueksaritanont

Structural Characterization of in Vivo Rat Glutathione Adducts and a Hydroxylated Metabolite of Simvastatin Hydroxy Acid
Drug Metab Dispos 2002 30: 225-230. [Abstract] [Full Text] [PDF]  

Abba J. Kastin, Melita B. Fasold, and James E. Zadina

Endomorphins, Met-Enkephalin, Tyr-MIF-1, and the P-glycoprotein Efflux System
Drug Metab Dispos 2002 30: 231-234. [Abstract] [Full Text] [PDF]  

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