Noab BioDiscoveries - Shaping Drug Discovery

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February 2003; 31 (2)   [Index by Author]  [Cover Caption]
       Articles
       Short Communications
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Articles:

Tyra M. Leazer and Curtis D. Klaassen
The Presence of Xenobiotic Transporters in Rat Placenta
Drug Metab Dispos 2003 31: 153-167. [Abstract] [Full Text] [PDF]  

Daniel Zalko, Rémi Costagliola, Céline Dorio, Estelle Rathahao, and Jean-Pierre Cravedi
In Vivo Metabolic Fate of the Xeno-Estrogen 4-n-Nonylphenol in Wistar Rats
Drug Metab Dispos 2003 31: 168-178. [Abstract] [Full Text] [PDF]  

Shigeyuki Kitamura, Tomoharu Suzuki, Tomoko Kadota, Mayumi Yoshida, Koji Ohashi, and Shigeru Ohta
In Vitro Metabolism of Fenthion and Fenthion Sulfoxide by Liver Preparations of Sea Bream, Goldfish, and Rats
Drug Metab Dispos 2003 31: 179-186. [Abstract] [Full Text] [PDF]  

Bjarte Furnes, Jinong Feng, Steve S. Sommer, and Daniel Schlenk
Identification of Novel Variants of the Flavin-Containing Monooxygenase Gene Family in African Americans
Drug Metab Dispos 2003 31: 187-193. [Abstract] [Full Text] [PDF]  

Eun J. Kim, Ae K. Lee, So H. Kim, Sang G. Kim, and Myung G. Lee
Pharmacokinetics and Pharmacodynamics of Intravenous Azosemide in Mutant Nagase Analbuminemic Rats
Drug Metab Dispos 2003 31: 194-201. [Abstract] [Full Text] [PDF]  

Jeremy T. Gamble, Kanji Nakatsu, and Gerald S. Marks
Comparison of the Formation of N-Alkylprotoporphyrin IX after Interaction of Porphyrinogenic Xenobiotics with Single cDNA-Expressed Human P450 Enzymes in Microsomes Prepared from Baculovirus-Infected Insect Cells and Human Lymphoblastoid Cell Lines+
Drug Metab Dispos 2003 31: 202-205. [Abstract] [Full Text] [PDF]  

Sudarsanan Varaprath, Joan M. McMahon, and Kathleen P. Plotzke
Metabolites of Hexamethyldisiloxane and Decamethylcyclopentasiloxane in Fischer 344 Rat Urine---A Comparison of a Linear and a Cyclic Siloxane
Drug Metab Dispos 2003 31: 206-214. [Abstract] [Full Text] [PDF]  

Wenji Yin, George A. Doss, Ralph A. Stearns, Ashok G. Chaudhary, Cornelis E. Hop, Ronald B. Franklin, and Sanjeev Kumar
A Novel P450-Catalyzed Transformation of the 2,2,6,6-Tetramethyl Piperidine Moiety to a 2,2-Dimethyl Pyrrolidine in Human Liver Microsomes: Characterization by High Resolution Quadrupole-Time-of-Flight Mass Spectrometry and 1H-NMR
Drug Metab Dispos 2003 31: 215-223. [Abstract] [Full Text] [PDF]  

A. David Rodrigues, Rita A. Halpin, Leslie A. Geer, Donghui Cui, Eric J. Woolf, Catherine Z. Matthews, Keith M. Gottesdiener, Patrick J. Larson, Kenneth C. Lasseter, and Nancy G. B. Agrawal
Absorption, Metabolism, and Excretion of Etoricoxib, a Potent and Selective Cyclooxygenase-2 Inhibitor, in Healthy Male Volunteers
Drug Metab Dispos 2003 31: 224-232. [Abstract] [Full Text] [PDF]  

Linda Bergander, Niklas Wahlström, Tomas Alsberg, Jan Bergman, Agneta Rannug, and Ulf Rannug
Characterization of in Vitro Metabolites of the Aryl Hydrocarbon Receptor Ligand 6-Formylindolo[3,2-b]carbazole by Liquid Chromatography-Mass Spectrometry and NMR.
Drug Metab Dispos 2003 31: 233-241. [Abstract] [Full Text] [PDF]  

Short Communications:

Mary E. Trudeau-Lame, Amit S. Kalgutkar, and Michael LaFontaine
Pharmacokinetics and Metabolism of the Reactive Oxygen Scavenger alpha -Phenyl-N-tert-butylnitrone in the Male Sprague-Dawley Rat
Drug Metab Dispos 2003 31: 147-152. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

Metabolism of PBN in male rat liver microsomes. See the article by Trudeau-Lame et al. on page 147 of this issue.



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