Articles:

Bindhu V. Karanam, Christopher J. Welch, Vijay G. Reddy, Jennifer Chilenski, Mirlinda Biba, and Stella Vincent

SPECIES DIFFERENTIAL STEREOSELECTIVE OXIDATION OF A METHYLSULFIDE METABOLITE OF MK-0767 [(±)-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL)PHENYL]METHYL]BENZAMIDE], A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DUAL AGONIST
Drug Metab Dispos 2004 32: 1061-1068. Published online June 30, 2004; 10.1124/dmd.104.000224 [Abstract] [Full Text] [PDF]  

Koji Nishi, Naoko Fukunaga, and Masaki Otagiri

CONSTRUCTION OF EXPRESSION SYSTEM FOR HUMAN ₁-ACID GLYCOPROTEIN IN PICHIA PASTORIS AND EVALUATION OF ITS DRUG-BINDING PROPERTIES
Drug Metab Dispos 2004 32: 1069-1074. Published online June 30, 2004; 10.1124/dmd.104.000513 [Abstract] [Full Text] [PDF]  

Changcheng Zhou, Michelle M. Tabb, Asal Sadatrafiei, Felix Grün, and Bruce Blumberg

TOCOTRIENOLS ACTIVATE THE STEROID AND XENOBIOTIC RECEPTOR, SXR, AND SELECTIVELY REGULATE EXPRESSION OF ITS TARGET GENES
Drug Metab Dispos 2004 32: 1075-1082. Published online July 21, 2004; 10.1124/dmd.104.000299 [Abstract] [Full Text] [PDF]  

Donavon J. McConn, II, Yvonne S. Lin, Kyle Allen, Kent L. Kunze, and Kenneth E. Thummel

DIFFERENCES IN THE INHIBITION OF CYTOCHROMES P450 3A4 AND 3A5 BY METABOLITE-INHIBITOR COMPLEX-FORMING DRUGS
Drug Metab Dispos 2004 32: 1083-1091. [Abstract] [Full Text] [PDF]  

Suresh K. Balani, Ping Li, Joanne Nguyen, Kym Cardoza, Hang Zeng, Dun-Xue Mu, Jing-Tao Wu, Liang-Shang Gan, and Frank W. Lee

EFFECTIVE DOSING REGIMEN OF 1-AMINOBENZOTRIAZOLE FOR INHIBITION OF ANTIPYRINE CLEARANCE IN GUINEA PIGS AND MICE USING SERIAL SAMPLING
Drug Metab Dispos 2004 32: 1092-1095. Published online June 24, 2004; 10.1124/dmd.104.000349 [Abstract] [Full Text] [PDF]  

Tadashi Hashimoto, Shinichi Narikawa, Xiu-Lin Huang, Tsuyoshi Minematsu, Takashi Usui, Hidetaka Kamimura, and Hitoshi Endou

CHARACTERIZATION OF THE RENAL TUBULAR TRANSPORT OF ZONAMPANEL, A NOVEL -AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID RECEPTOR ANTAGONIST, BY HUMAN ORGANIC ANION TRANSPORTERS
Drug Metab Dispos 2004 32: 1096-1102. [Abstract] [Full Text] [PDF]  

Toshiki Tabata, Miki Katoh, Shogo Tokudome, Miki Nakajima, and Tsuyoshi Yokoi

IDENTIFICATION OF THE CYTOSOLIC CARBOXYLESTERASE CATALYZING THE 5'-DEOXY-5-FLUOROCYTIDINE FORMATION FROM CAPECITABINE IN HUMAN LIVER
Drug Metab Dispos 2004 32: 1103-1110. Published online July 21, 2004; 10.1124/dmd.104.000554 [Abstract] [Full Text] [PDF]  

Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey A. Ivashchenko, Nikolay P. Savchuk, and Tatiana Nikolskaya

QUANTITATIVE STRUCTURE-METABOLISM RELATIONSHIP MODELING OF METABOLIC N-DEALKYLATION REACTION RATES
Drug Metab Dispos 2004 32: 1111-1120. Published online July 21, 2004; 10.1124/dmd.104.000364 [Abstract] [Full Text] [PDF]  

Nina Isoherranen, Kent L. Kunze, Kyle E. Allen, Wendel L. Nelson, and Kenneth E. Thummel

ROLE OF ITRACONAZOLE METABOLITES IN CYP3A4 INHIBITION
Drug Metab Dispos 2004 32: 1121-1131. Published online July 8, 2004; 10.1124/dmd.104.000315 [Abstract] [Full Text] [PDF]  

L. Sanderson, G. W. Taylor, E. O. Aboagye, J. P. Alao, J. R. Latigo, R. C. Coombes, and D. M. Vigushin

PLASMA PHARMACOKINETICS AND METABOLISM OF THE HISTONE DEACETYLASE INHIBITOR TRICHOSTATIN A AFTER INTRAPERITONEAL ADMINISTRATION TO MICE
Drug Metab Dispos 2004 32: 1132-1138. Published online July 21, 2004; 10.1124/dmd.104.000638 [Abstract] [Full Text] [PDF]  

Phillip M. Gerk, Wei Li, and Mary Vore

ESTRADIOL 3-GLUCURONIDE IS TRANSPORTED BY THE MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 2 BUT DOES NOT ACTIVATE THE ALLOSTERIC SITE BOUND BY ESTRADIOL 17-GLUCURONIDE
Drug Metab Dispos 2004 32: 1139-1145. Published online July 27, 2004; 10.1124/dmd.104.000372 [Abstract] [Full Text] [PDF]  

Mary F. Paine, Anne B. Criss, and Paul B. Watkins

TWO MAJOR GRAPEFRUIT JUICE COMPONENTS DIFFER IN INTESTINAL CYP3A4 INHIBITION KINETIC AND BINDING PROPERTIES
Drug Metab Dispos 2004 32: 1146-1153. Published online July 21, 2004; 10.1124/dmd.104.000547 [Abstract] [Full Text] [PDF]  

Vijay Bhasker G. Reddy, George A. Doss, Mellissa Creighton, Christopher J. Kochansky, Stella H. Vincent, Ronald B. Franklin, and Bindhu V. Karanam

IDENTIFICATION AND METABOLISM OF A NOVEL DIHYDROHYDROXY-S-GLUTATHIONYL CONJUGATE OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONIST, MK-0767 [(±)-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL) PHENYL]METHYL]BENZAMIDE], IN RATS
Drug Metab Dispos 2004 32: 1154-1161. Published online June 30, 2004; 10.1124/dmd.104.000240 [Abstract] [Full Text] [PDF]  

Li-Quan Wang, Charles N. Falany, and Margaret O. James

TRICLOSAN AS A SUBSTRATE AND INHIBITOR OF 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE-SULFOTRANSFERASE AND UDP-GLUCURONOSYL TRANSFERASE IN HUMAN LIVER FRACTIONS
Drug Metab Dispos 2004 32: 1162-1169. Published online July 21, 2004; 10.1124/dmd.104.000273 [Abstract] [Full Text] [PDF]  

Tomomi Furihata, Masakiyo Hosokawa, Nao Koyano, Takahiro Nakamura, Tetsuo Satoh, and Kan Chiba

IDENTIFICATION OF DI-(2-ETHYLHEXYL) PHTHALATE-INDUCED CARBOXYLESTERASE 1 IN C57BL/6 MOUSE LIVER MICROSOMES: PURIFICATION, CDNA CLONING, AND BACULOVIRUS-MEDIATED EXPRESSION
Drug Metab Dispos 2004 32: 1170-1177. Published online July 21, 2004; 10.1124/dmd.104.000620 [Abstract] [Full Text] [PDF]  

Daigo Murata, Yoshio Endo, Tohru Obata, Kazuki Sakamoto, Yasuhiro Syouji, Masakazu Kadohira, Akira Matsuda, and Takuma Sasaki

A CRUCIAL ROLE OF URIDINE/CYTIDINE KINASE 2 IN ANTITUMOR ACTIVITY OF 3'-ETHYNYL NUCLEOSIDES
Drug Metab Dispos 2004 32: 1178-1182. Published online July 27, 2004; 10.1124/dmd.104.000737 [Abstract] [Full Text] [PDF]  

Konstantin V. Balakin, Sean Ekins, Andrey Bugrim, Yan A. Ivanenkov, Dmitry Korolev, Yuri V. Nikolsky, Andrey V. Skorenko, Andrey A. Ivashchenko, Nikolay P. Savchuk, and Tatiana Nikolskaya

KOHONEN MAPS FOR PREDICTION OF BINDING TO HUMAN CYTOCHROME P450 3A4
Drug Metab Dispos 2004 32: 1183-1189. Published online July 1, 2004; 10.1124/dmd.104.000356 [Abstract] [Full Text] [PDF]  

Michael J. Potchoiba and Mark R. Nocerini

UTILITY OF WHOLE-BODY AUTORADIOLUMINOGRAPHY IN DRUG DISCOVERY FOR THE QUANTIFICATION OF TRITIUM-LABELED DRUG CANDIDATES
Drug Metab Dispos 2004 32: 1190-1198. [Abstract] [Full Text] [PDF]  

Short Communications:

Yuji Ishii, Aya Miyoshi, Daisuke Maji, Hideyuki Yamada, and Kazuta Oguri

SIMULTANEOUS EXPRESSION OF GUINEA PIG UDP-GLUCURONOSYLTRANSFERASE 2B21 (UGT2B21) AND 2B22 IN COS-7 CELLS ENHANCES UGT2B21-CATALYZED CHLORAMPHENICOL GLUCURONIDATION
Drug Metab Dispos 2004 32: 1057-1060. [Abstract] [Full Text] [PDF]  

Errata:

CORRECTION TO "COMPARISON OF PREDICTION METHODS FOR IN VIVO CLEARANCE OF (S,S)-3-[3-(METHYLSULFONYL)PHENYL]-1-PROPYLPIPERIDINE HYDROCHLORIDE, A DOPAMINE D2 RECEPTOR ANTAGONIST, IN HUMANS"
Drug Metab Dispos 2004 32: 1199. [Full Text] [PDF]  

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