Articles:

Franca M. Buratti, Alessandra D'Aniello, Maria Teresa Volpe, Annarita Meneguz, and Emanuela Testai

MALATHION BIOACTIVATION IN THE HUMAN LIVER: THE CONTRIBUTION OF DIFFERENT CYTOCHROME P450 ISOFORMS
Drug Metab Dispos 2005 33: 295-302. Published online November 22, 2004; 10.1124/dmd.104.001693 [Abstract] [Full Text] [PDF]  

Theresa Mariero Klees, Pamela Sheffels, Ola Dale, and Evan D. Kharasch

METABOLISM OF ALFENTANIL BY CYTOCHROME P4503A (CYP3A) ENZYMES
Drug Metab Dispos 2005 33: 303-311. Published online November 22, 2004; 10.1124/dmd.104.002709 [Abstract] [Full Text] [PDF]  

Erin E. Bessette, Michael J. Fasco, Brian T. Pentecost, and Laurence S. Kaminsky

MECHANISMS OF ARSENITE-MEDIATED DECREASES IN BENZO[K]FLUORANTHENE-INDUCED HUMAN CYTOCHROME P4501A1 LEVELS IN HEPG2 CELLS
Drug Metab Dispos 2005 33: 312-320. Published online December 2, 2004; 10.1124/dmd.104.002212 [Abstract] [Full Text] [PDF]  

Xiao-fei Zhou, Linping Zhang, Elaine Tseng, Elizabeth Scott-Ramsay, Jerome J. Schentag, Robert A. Coburn, and Marilyn E. Morris

NEW 4-ARYL-1,4-DIHYDROPYRIDINES AND 4-ARYLPYRIDINES AS P-GLYCOPROTEIN INHIBITORS
Drug Metab Dispos 2005 33: 321-328. Published online December 7, 2004; 10.1124/dmd.104.002089 [Abstract] [Full Text] [PDF]  

Hui Tian, Junhai Ou, Stephen C. Strom, and Raman Venkataramanan

PHARMACOKINETICS OF TACROLIMUS AND MYCOPHENOLIC ACID ARE ALTERED, BUT RECOVER AT DIFFERENT TIMES DURING HEPATIC REGENERATION IN RATS
Drug Metab Dispos 2005 33: 329-335. Published online November 2, 2004; 10.1124/dmd.104.002287 [Abstract] [Full Text] [PDF]  

Shou-Lin Wang, Xiao-Yang He, and Jun-Yan Hong

HUMAN CYTOCHROME P450 2S1: LACK OF ACTIVITY IN THE METABOLIC ACTIVATION OF SEVERAL CIGARETTE SMOKE CARCINOGENS AND IN THE METABOLISM OF NICOTINE
Drug Metab Dispos 2005 33: 336-340. Published online December 17, 2004; 10.1124/dmd.104.002923 [Abstract] [Full Text] [PDF]  

Shuzhong Zhang, Xiaodong Wang, Kazuko Sagawa, and Marilyn E. Morris

FLAVONOIDS CHRYSIN AND BENZOFLAVONE, POTENT BREAST CANCER RESISTANCE PROTEIN INHIBITORS, HAVE NO SIGNIFICANT EFFECT ON TOPOTECAN PHARMACOKINETICS IN RATS OR MDR1A/1B (–/–) MICE
Drug Metab Dispos 2005 33: 341-348. Published online December 17, 2004; 10.1124/dmd.104.002501 [Abstract] [Full Text] [PDF]  

Annalise Di Marco, Isabella Marcucci, Maria Verdirame, José Pérez, Manuel Sanchez, Fernando Peláez, Ashok Chaudhary, and Ralph Laufer

DEVELOPMENT AND VALIDATION OF A HIGH-THROUGHPUT RADIOMETRIC CYP3A4/5 INHIBITION ASSAY USING TRITIATED TESTOSTERONE
Drug Metab Dispos 2005 33: 349-358. Published online December 17, 2004; 10.1124/dmd.104.002873 [Abstract] [Full Text] [PDF]  

Annalise Di Marco, Isabella Marcucci, Ashok Chaudhary, Marina Taliani, and Ralph Laufer

DEVELOPMENT AND VALIDATION OF A HIGH-THROUGHPUT RADIOMETRIC CYP2C9 INHIBITION ASSAY USING TRITIATED DICLOFENAC
Drug Metab Dispos 2005 33: 359-364. Published online December 17, 2004; 10.1124/dmd.104.002915 [Abstract] [Full Text] [PDF]  

Negar Gharavi and Ayman O. S. El-Kadi

tert-BUTYLHYDROQUINONE IS A NOVEL ARYL HYDROCARBON RECEPTOR LIGAND
Drug Metab Dispos 2005 33: 365-372. Published online December 17, 2004; 10.1124/dmd.104.002253 [Abstract] [Full Text] [PDF]  

Koichi Haraguchi, Nobuyuki Koga, and Yoshihisa Kato

COMPARATIVE METABOLISM OF POLYCHLORINATED BIPHENYLS AND TISSUE DISTRIBUTION OF PERSISTENT METABOLITES IN RATS, HAMSTERS, AND GUINEA PIGS
Drug Metab Dispos 2005 33: 373-380. Published online December 17, 2004; 10.1124/dmd.104.002444 [Abstract] [Full Text] [PDF]  

Makoto Inada, Yukihiro Hirao, Toshihisa Koga, Minoru Itose, Jun-ichi Kunizaki, Takefumi Shimizu, and Hitoshi Sato

RELATIONSHIPS AMONG PLASMA [2-¹³C]URACIL CONCENTRATIONS, BREATH ¹³CO₂ EXPIRATION, AND DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) ACTIVITY IN THE LIVER IN NORMAL AND DPD-DEFICIENT DOGS
Drug Metab Dispos 2005 33: 381-387. Published online December 22, 2004; 10.1124/dmd.104.001032 [Abstract] [Full Text] [PDF]  

Pieter P. Annaert and Kim L. R. Brouwer

ASSESSMENT OF DRUG INTERACTIONS IN HEPATOBILIARY TRANSPORT USING RHODAMINE 123 IN SANDWICH-CULTURED RAT HEPATOCYTES
Drug Metab Dispos 2005 33: 388-394. Published online December 17, 2004; 10.1124/dmd.104.001669 [Abstract] [Full Text] [PDF]  

Li-Heng Pao, Cheng-Huei Hsiong, Oliver Yoa-Pu Hu, Jhi-Jung Wang, and Shung-Tai Ho

IN VITRO AND IN VIVO EVALUATION OF THE METABOLISM AND PHARMACOKINETICS OF SEBACOYL DINALBUPHINE
Drug Metab Dispos 2005 33: 395-402. Published online December 17, 2004; 10.1124/dmd.104.002451 [Abstract] [Full Text] [PDF]  

Hidefumi Kaji and Toshiyuki Kume

REGIOSELECTIVE GLUCURONIDATION OF DENOPAMINE: MARKED SPECIES DIFFERENCES AND IDENTIFICATION OF HUMAN UDP-GLUCURONOSYLTRANSFERASE ISOFORM
Drug Metab Dispos 2005 33: 403-412. Published online December 17, 2004; 10.1124/dmd.104.002667 [Abstract] [Full Text] [PDF]  

Robert L. Walsky, R. Scott Obach, Emily A. Gaman, Jean-Paul R. Gleeson, and William R. Proctor

SELECTIVE INHIBITION OF HUMAN CYTOCHROME P4502C8 BY MONTELUKAST
Drug Metab Dispos 2005 33: 413-418. Published online December 17, 2004; 10.1124/dmd.104.002766 [Abstract] [Full Text] [PDF]  

Rupert P. Austin, Patrick Barton, Sarfraz Mohmed, and Robert J. Riley

THE BINDING OF DRUGS TO HEPATOCYTES AND ITS RELATIONSHIP TO PHYSICOCHEMICAL PROPERTIES
Drug Metab Dispos 2005 33: 419-425. Published online December 22, 2004; 10.1124/dmd.104.002436 [Abstract] [Full Text] [PDF]  

Mary F. Paine, Shana S. Ludington, Mei-Ling Chen, Paul W. Stewart, Shiew-Mei Huang, and Paul B. Watkins

DO MEN AND WOMEN DIFFER IN PROXIMAL SMALL INTESTINAL CYP3A OR P-GLYCOPROTEIN EXPRESSION?
Drug Metab Dispos 2005 33: 426-433. Published online December 17, 2004; 10.1124/dmd.104.002469 [Abstract] [Full Text] [PDF]  

Takashi Nozawa, Hironobu Minami, Shigeki Sugiura, Akira Tsuji, and Ikumi Tamai

ROLE OF ORGANIC ANION TRANSPORTER OATP1B1 (OATP-C) IN HEPATIC UPTAKE OF IRINOTECAN AND ITS ACTIVE METABOLITE, 7-ETHYL-10-HYDROXYCAMPTOTHECIN: IN VITRO EVIDENCE AND EFFECT OF SINGLE NUCLEOTIDE POLYMORPHISMS
Drug Metab Dispos 2005 33: 434-439. Published online December 17, 2004; 10.1124/dmd.104.001909 [Abstract] [Full Text] [PDF]  

Jong-Hyuk Sung, Kyung-Ha Yu, Jin-Sun Park, Takashi Tsuruo, Dae-Duk Kim, Chang-Koo Shim, and Suk-Jae Chung

SATURABLE DISTRIBUTION OF TACRINE INTO THE STRIATAL EXTRACELLULAR FLUID OF THE RAT: EVIDENCE OF INVOLVEMENT OF MULTIPLE ORGANIC CATION TRANSPORTERS IN THE TRANSPORT
Drug Metab Dispos 2005 33: 440-448. Published online November 16, 2004; 10.1124/dmd.104.002220 [Abstract] [Full Text] [PDF]  

Connie Cheung, Ai-Ming Yu, Jerrold M. Ward, Kristopher W. Krausz, Taro E. Akiyama, Lionel Feigenbaum, and Frank J. Gonzalez

THE CYP2E1-HUMANIZED TRANSGENIC MOUSE: ROLE OF CYP2E1 IN ACETAMINOPHEN HEPATOTOXICITY
Drug Metab Dispos 2005 33: 449-457. Published online December 2, 2004; 10.1124/dmd.104.002402 [Abstract] [Full Text] [PDF]  

Nahoko Kaniwa, Kouichi Kurose, Hideto Jinno, Toshiko Tanaka-Kagawa, Yoshiro Saito, Mayumi Saeki, Jun-ichi Sawada, Masahiro Tohkin, and Ryuichi Hasegawa

RACIAL VARIABILITY IN HAPLOTYPE FREQUENCIES OF UGT1A1 AND GLUCURONIDATION ACTIVITY OF A NOVEL SINGLE NUCLEOTIDE POLYMORPHISM 686C> T (P229L) FOUND IN AN AFRICAN-AMERICAN
Drug Metab Dispos 2005 33: 458-465. Published online November 30, 2004; 10.1124/dmd.104.001800 [Abstract] [Full Text] [PDF]  

M. Delaforge, A. Pruvost, L. Perrin, and F. André

CYTOCHROME P450-MEDIATED OXIDATION OF GLUCURONIDE DERIVATIVES: EXAMPLE OF ESTRADIOL-17ß-GLUCURONIDE OXIDATION TO 2-HYDROXY-ESTRADIOL-17ß-GLUCURONIDE BY CYP 2C8
Drug Metab Dispos 2005 33: 466-473. Published online December 17, 2004; 10.1124/dmd.104.002097 [Abstract] [Full Text] [PDF]  

Accelerated Communications:

Sean Ekins, Eugene Kirillov, Eugene A. Rakhmatulin, and Tatiana Nikolskaya

A NOVEL METHOD FOR VISUALIZING NUCLEAR HORMONE RECEPTOR NETWORKS RELEVANT TO DRUG METABOLISM
Drug Metab Dispos 2005 33: 474-481. Published online December 17, 2004; 10.1124/dmd.104.002717 [Abstract] [Full Text] [PDF]  

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