Articles:

Terrilyn A. Richardson, Melanie Sherman, Leposava Antonovic, Sean S. Kardar, Henry W. Strobel, Daniel Kalman, and Edward T. Morgan

HEPATIC AND RENAL CYTOCHROME P450 GENE REGULATION DURING CITROBACTER RODENTIUM INFECTION IN WILD-TYPE AND TOLL-LIKE RECEPTOR 4 MUTANT MICE
Drug Metab Dispos 2006 34: 354-360. Published online December 8, 2005; 10.1124/dmd.105.007393 [Abstract] [Full Text] [PDF]  

Josie L. Falany, Daniel E. Pilloff, Thomas S. Leyh, and Charles N. Falany

SULFATION OF RALOXIFENE AND 4-HYDROXYTAMOXIFEN BY HUMAN CYTOSOLIC SULFOTRANSFERASES
Drug Metab Dispos 2006 34: 361-368. Published online December 28, 2005; 10.1124/dmd.105.006551 [Abstract] [Full Text] [PDF] [Data Supplement]   

Masato Nakamura, Yasunori Kawakita, Akito Yasuhara, Yoshiki Fukasawa, Koji Yoshida, Kazunari Sakagami, and Atsuro Nakazato

IN VITRO AND IN VIVO EVALUATION OF THE METABOLISM AND BIOAVAILABILITY OF ESTER PRODRUGS OF MGS0039 (3-(3,4-DICHLOROBENZYLOXY)-2-AMINO-6-FLUOROBICYCLO[3.1.0]HEXANE-2,6-DICARBOXYLIC ACID), A POTENT METABOTROPIC GLUTAMATE RECEPTOR ANTAGONIST
Drug Metab Dispos 2006 34: 369-374. Published online December 2, 2005; 10.1124/dmd.105.006213 [Abstract] [Full Text] [PDF]  

Mohamad Shebley, Monica I. Jushchyshyn, and Paul F. Hollenberg

SELECTIVE PATHWAYS FOR THE METABOLISM OF PHENCYCLIDINE BY CYTOCHROME P450 2B ENZYMES: IDENTIFICATION OF ELECTROPHILIC METABOLITES, GLUTATHIONE, AND N-ACETYL CYSTEINE ADDUCTS
Drug Metab Dispos 2006 34: 375-383. Published online December 2, 2005; 10.1124/dmd.105.007047 [Abstract] [Full Text] [PDF]  

Suresh K. Balani, Nelamangala V. Nagaraja, Mark G. Qian, Arnaldo O. Costa, J. Scott Daniels, Hua Yang, Prakash R. Shimoga, Jing-Tao Wu, Liang-Shang Gan, Frank W. Lee, and Gerald T. Miwa

EVALUATION OF MICRODOSING TO ASSESS PHARMACOKINETIC LINEARITY IN RATS USING LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY
Drug Metab Dispos 2006 34: 384-388. Published online December 2, 2005; 10.1124/dmd.105.007195 [Abstract] [Full Text] [PDF]  

Sathanandam S. Anand, Kyu-Bong Kim, Stephanie Padilla, Srinivasa Muralidhara, Hyo J. Kim, Jeffrey W. Fisher, and James V. Bruckner

ONTOGENY OF HEPATIC AND PLASMA METABOLISM OF DELTAMETHRIN IN VITRO: ROLE IN AGE-DEPENDENT ACUTE NEUROTOXICITY
Drug Metab Dispos 2006 34: 389-397. Published online December 2, 2005; 10.1124/dmd.105.007807 [Abstract] [Full Text] [PDF]  

Kenji Masaki, Megumi Taketani, and Teruko Imai

FIRST-PASS HYDROLYSIS OF A PROPRANOLOL ESTER DERIVATIVE IN RAT SMALL INTESTINE
Drug Metab Dispos 2006 34: 398-404. Published online December 2, 2005; 10.1124/dmd.105.007682 [Abstract] [Full Text] [PDF]  

Alexander Anapolsky, Shirley Teng, Santosh Dixit, and Micheline Piquette-Miller

THE ROLE OF PREGNANE X RECEPTOR IN 2-ACETYLAMINOFLUORENE-MEDIATED INDUCTION OF DRUG TRANSPORT AND -METABOLIZING ENZYMES IN MICE
Drug Metab Dispos 2006 34: 405-409. Published online December 28, 2005; 10.1124/dmd.105.006197 [Abstract] [Full Text] [PDF]  

Chellappagounder Thangavel, Wojciech Dworakowski, and Bernard H. Shapiro

INDUCIBILITY OF MALE-SPECIFIC ISOFORMS OF CYTOCHROME P450 BY SEX-DEPENDENT GROWTH HORMONE PROFILES IN HEPATOCYTE CULTURES FROM MALE BUT NOT FEMALE RATS
Drug Metab Dispos 2006 34: 410-419. Published online December 8, 2005; 10.1124/dmd.105.007716 [Abstract] [Full Text] [PDF]  

Jie Ling, Kim A. Johnson, Zhuang Miao, Ashok Rakhit, Michael P. Pantze, Marta Hamilton, Bert L. Lum, and Chandra Prakash

METABOLISM AND EXCRETION OF ERLOTINIB, A SMALL MOLECULE INHIBITOR OF EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE, IN HEALTHY MALE VOLUNTEERS
Drug Metab Dispos 2006 34: 420-426. Published online December 28, 2005; 10.1124/dmd.105.007765 [Abstract] [Full Text] [PDF]  

Lifei Wang, Donglu Zhang, Arun Swaminathan, Yongjun Xue, Peter T. Cheng, Shung Wu, Rogelio Mosqueda-Garcia, Catherine Aurang, Donald W. Everett, and W. Griffith Humphreys

GLUCURONIDATION AS A MAJOR METABOLIC CLEARANCE PATHWAY OF ¹⁴C-LABELED MURAGLITAZAR IN HUMANS: METABOLIC PROFILES IN SUBJECTS WITH OR WITHOUT BILE COLLECTION
Drug Metab Dispos 2006 34: 427-439. Published online December 28, 2005; 10.1124/dmd.105.007617 [Abstract] [Full Text] [PDF]  

Yan Chang, David E. Moody, and Elinore F. McCance-Katz

NOVEL METABOLITES OF BUPRENORPHINE DETECTED IN HUMAN LIVER MICROSOMES AND HUMAN URINE
Drug Metab Dispos 2006 34: 440-448. Published online December 28, 2005; 10.1124/dmd.105.006148 [Abstract] [Full Text] [PDF]  

Verawan Uchaipichat, Peter I. Mackenzie, David J. Elliot, and John O. Miners

SELECTIVITY OF SUBSTRATE (TRIFLUOPERAZINE) AND INHIBITOR (AMITRIPTYLINE, ANDROSTERONE, CANRENOIC ACID, HECOGENIN, PHENYLBUTAZONE, QUINIDINE, QUININE, AND SULFINPYRAZONE) "PROBES" FOR HUMAN UDP-GLUCURONOSYLTRANSFERASES
Drug Metab Dispos 2006 34: 449-456. Published online December 28, 2005; 10.1124/dmd.105.007369 [Abstract] [Full Text] [PDF]  

M. Ballent, A. Lifschitz, G. Virkel, J. Sallovitz, and C. Lanusse

MODULATION OF THE P-GLYCOPROTEIN-MEDIATED INTESTINAL SECRETION OF IVERMECTIN: IN VITRO AND IN VIVO ASSESSMENTS
Drug Metab Dispos 2006 34: 457-463. Published online December 28, 2005; 10.1124/dmd.105.007757 [Abstract] [Full Text] [PDF]  

Hans-Jörg Martin, Ursula Breyer-Pfaff, Vladimir Wsol, Simone Venz, Simone Block, and Edmund Maser

PURIFICATION AND CHARACTERIZATION OF AKR1B10 FROM HUMAN LIVER: ROLE IN CARBONYL REDUCTION OF XENOBIOTICS
Drug Metab Dispos 2006 34: 464-470. Published online December 28, 2005; 10.1124/dmd.105.007971 [Abstract] [Full Text] [PDF]  

Jacek Wójcikowski, Patrick Maurel, and Wladyslawa A. Daniel

CHARACTERIZATION OF HUMAN CYTOCHROME P450 ENZYMES INVOLVED IN THE METABOLISM OF THE PIPERIDINE-TYPE PHENOTHIAZINE NEUROLEPTIC THIORIDAZINE
Drug Metab Dispos 2006 34: 471-476. Published online November 4, 2005; 10.1124/dmd.105.006445 [Abstract] [Full Text] [PDF]  

Yazen Alnouti, Jay S. Petrick, and Curtis D. Klaassen

TISSUE DISTRIBUTION AND ONTOGENY OF ORGANIC CATION TRANSPORTERS IN MICE
Drug Metab Dispos 2006 34: 477-482. Published online December 28, 2005; 10.1124/dmd.105.006932 [Abstract] [Full Text] [PDF]  

Di Wu, Zengru Wu, Jun Yang, Vipin A. Nair, Duane D. Miller, and James T. Dalton

PHARMACOKINETICS AND METABOLISM OF A SELECTIVE ANDROGEN RECEPTOR MODULATOR IN RATS: IMPLICATION OF MOLECULAR PROPERTIES AND INTENSIVE METABOLIC PROFILE TO INVESTIGATE IDEAL PHARMACOKINETIC CHARACTERISTICS OF A PROPANAMIDE IN PRECLINICAL STUDY
Drug Metab Dispos 2006 34: 483-494. Published online December 28, 2005; 10.1124/dmd.105.006643 [Abstract] [Full Text] [PDF]  

Sean Ekins, Sergey Andreyev, Andy Ryabov, Eugene Kirillov, Eugene A. Rakhmatulin, Svetlana Sorokina, Andrej Bugrim, and Tatiana Nikolskaya

A COMBINED APPROACH TO DRUG METABOLISM AND TOXICITY ASSESSMENT
Drug Metab Dispos 2006 34: 495-503. Published online December 28, 2005; 10.1124/dmd.105.008458 [Abstract] [Full Text] [PDF] [Data Supplement]   

Short Communications:

Frank Pietruck, Markus Horbelt, Thorsten Feldkamp, Katrin Engeln, Stefan Herget-Rosenthal, Thomas Philipp, and Andreas Kribben

DIGITAL FLUORESCENCE IMAGING OF ORGANIC CATION TRANSPORT IN FRESHLY ISOLATED RAT PROXIMAL TUBULES
Drug Metab Dispos 2006 34: 339-342. Published online December 8, 2005; 10.1124/dmd.105.006403 [Abstract] [Full Text] [PDF]  

Muneaki Hidaka, Manabu Okumura, Tetsuya Ogikubo, Hirofumi Kai, Ken-Ichi Fujita, Tomomi Iwakiri, Keishi Yamasaki, Nao Setoguchi, Naoya Matsunaga, and Kazuhiko Arimori

TRANSIENT INHIBITION OF CYP3A IN RATS BY STAR FRUIT JUICE
Drug Metab Dispos 2006 34: 343-345. Published online December 2, 2005; 10.1124/dmd.105.006486 [Abstract] [Full Text] [PDF]  

Thomas Walle, U. Kristina Walle, David Sedmera, and Mitch Klausner

BENZO[A]PYRENE-INDUCED ORAL CARCINOGENESIS AND CHEMOPREVENTION: STUDIES IN BIOENGINEERED HUMAN TISSUE
Drug Metab Dispos 2006 34: 346-350. Published online December 28, 2005; 10.1124/dmd.105.007948 [Abstract] [Full Text] [PDF]  

Terrilyn A. Richardson, Melanie Sherman, Daniel Kalman, and Edward T. Morgan

EXPRESSION OF UDP-GLUCURONOSYLTRANSFERASE ISOFORM mRNAS DURING INFLAMMATION AND INFECTION IN MOUSE LIVER AND KIDNEY
Drug Metab Dispos 2006 34: 351-353. Published online December 8, 2005; 10.1124/dmd.105.007435 [Abstract] [Full Text] [PDF] [Data Supplement]   

Letters to the Editor:

Andrea Gaedigk and J. Steven Leeder

COMMENTS ON HOSKINS ET AL. [(2005) DRUG METAB DISPOS 33:1564–1565]
Drug Metab Dispos 2006 34: 504-505. [Full Text] [PDF]  

Harish V. Pai and Vijayalakshmi Ravindranath

RESPONSE TO COMMENTS ON HOSKINS ET AL. [(2005) DRUG METAB DISPOS 33:1564–1565]
Drug Metab Dispos 2006 34: 506. [Full Text] [PDF]  

Iftekhar Mahmood

COMMENTS ON "A MATHEMATICAL DESCRIPTION OF THE FUNCTIONALITY OF CORRECTION FACTORS USED IN ALLOMETRY FOR PREDICTING HUMAN DRUG CLEARANCE"
Drug Metab Dispos 2006 34: 507-509. [Abstract] [Full Text] [PDF]  

Huadong Tang and Michael Mayersohn

RESPONSE TO COMMENTS ON "A MATHEMATICAL DESCRIPTION OF THE FUNCTIONALITY OF CORRECTION FACTORS USED IN ALLOMETRY FOR PREDICTING HUMAN DRUG CLEARANCE"
Drug Metab Dispos 2006 34: 510-511. [Full Text] [PDF]  

Errata:

CORRECTION TO "METABOLISM OF THE PSYCHOTOMIMETIC TRYPTAMINE DERIVATIVE 5-METHOXY-N,N-DIISOPROPYLTRYPTAMINE IN HUMANS: IDENTIFICATION AND QUANTIFICATION OF ITS URINARY METABOLITES"
Drug Metab Dispos 2006 34: 512. [Full Text] [PDF]  

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