Articles:

Andrew L. Hong, Dezheng Huo, Hee-Jin Kim, Qun Niu, Donna L. Fackenthal, Shelly A. Cummings, Esther M. John, Dee W. West, Alice S. Whittemore, Soma Das, and Olufunmilayo I. Olopade

UDP-Glucuronosyltransferase 1A1 Gene Polymorphisms and Total Bilirubin Levels in an Ethnically Diverse Cohort of Women
Drug Metab Dispos 2007 35: 1254-1261. Published online May 3, 2007; 10.1124/dmd.106.014183 [Abstract] [Full Text] [PDF]  

Gary Williamson, Isabelle Aeberli, Laurence Miguet, Ziding Zhang, M.-Belen Sanchez, Vanessa Crespy, Denis Barron, Paul Needs, Paul A. Kroon, H. Glavinas, Peter Krajcsi, and Martin Grigorov

Interaction of Positional Isomers of Quercetin Glucuronides with the Transporter ABCC2 (cMOAT, MRP2)
Drug Metab Dispos 2007 35: 1262-1268. Published online May 3, 2007; 10.1124/dmd.106.014241 [Abstract] [Full Text] [PDF]  

Xiaoyun Ye, Amber M. Bishop, Larry L. Needham, and Antonia M. Calafat

Identification of Metabolites of 4-Nonylphenol Isomer 4-(3',6'-Dimethyl-3'-Heptyl) Phenol by Rat and Human Liver Microsomes
Drug Metab Dispos 2007 35: 1269-1274. Published online April 25, 2007; 10.1124/dmd.107.015578 [Abstract] [Full Text] [PDF]  

Tomohiro Nishimura, Nobuyuki Amano, Yoshiyuki Kubo, Midori Ono, Yukio Kato, Hisashi Fujita, Yoshiaki Kimura, and Akira Tsuji

Asymmetric Intestinal First-Pass Metabolism Causes Minimal Oral Bioavailability of Midazolam in Cynomolgus Monkey
Drug Metab Dispos 2007 35: 1275-1284. Published online April 30, 2007; 10.1124/dmd.106.013037 [Abstract] [Full Text] [PDF]  

Sam C.S. Au-Yeung, K. Wayne Riggs, Nancy Gruber, and Dan W. Rurak

The Use of Microdialysis for the Study of Drug Kinetics: Central Nervous System Pharmacokinetics of Diphenhydramine in Fetal, Newborn, and Adult Sheep
Drug Metab Dispos 2007 35: 1285-1291. Published online May 7, 2007; 10.1124/dmd.106.013995 [Abstract] [Full Text] [PDF]  

Hongwu Shen, Minxia M. He, Houfu Liu, Steven A. Wrighton, Li Wang, Bin Guo, and Chuan Li

Comparative Metabolic Capabilities and Inhibitory Profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17
Drug Metab Dispos 2007 35: 1292-1300. Published online April 30, 2007; 10.1124/dmd.107.015354 [Abstract] [Full Text] [PDF]  

Bennett Ma, Stacey L. Polsky-Fisher, Stanley Vickers, Donghui Cui, and A. David Rodrigues

Cytochrome P450 3A-Dependent Metabolism of a Potent and Selective -Aminobutyric Acid_A2/3 Receptor Agonist in Vitro: Involvement of Cytochrome P450 3A5 Displaying Biphasic Kinetics
Drug Metab Dispos 2007 35: 1301-1307. Published online April 25, 2007; 10.1124/dmd.107.014753 [Abstract] [Full Text] [PDF]  

Johannes Noé, Renée Portmann, Marie-Elise Brun, and Christoph Funk

Substrate-Dependent Drug-Drug Interactions between Gemfibrozil, Fluvastatin and Other Organic Anion-Transporting Peptide (OATP) Substrates on OATP1B1, OATP2B1, and OATP1B3
Drug Metab Dispos 2007 35: 1308-1314. Published online April 30, 2007; 10.1124/dmd.106.012930 [Abstract] [Full Text] [PDF]  

Theunis C. Goosen, Jonathan N. Bauman, John A. Davis, Chongwoo Yu, Susan I. Hurst, J. Andrew Williams, and Cho-Ming Loi

Atorvastatin Glucuronidation Is Minimally and Nonselectively Inhibited by the Fibrates Gemfibrozil, Fenofibrate, and Fenofibric Acid
Drug Metab Dispos 2007 35: 1315-1324. Published online April 30, 2007; 10.1124/dmd.107.015230 [Abstract] [Full Text] [PDF]  

David Hallifax and J. Brian Houston

Saturable Uptake of Lipophilic Amine Drugs into Isolated Hepatocytes: Mechanisms and Consequences for Quantitative Clearance Prediction
Drug Metab Dispos 2007 35: 1325-1332. Published online April 30, 2007; 10.1124/dmd.107.015131 [Abstract] [Full Text] [PDF]  

Constanze Hilgendorf, Gustav Ahlin, Annick Seithel, Per Artursson, Anna-Lena Ungell, and Johan Karlsson

Expression of Thirty-six Drug Transporter Genes in Human Intestine, Liver, Kidney, and Organotypic Cell Lines
Drug Metab Dispos 2007 35: 1333-1340. Published online May 11, 2007; 10.1124/dmd.107.014902 [Abstract] [Full Text] [PDF]  

Karthik Venkatakrishnan, Elaine Tseng, Frederick R. Nelson, Hans Rollema, Jonathan L. French, Irina V. Kaplan, Weldon E. Horner, and Megan A. Gibbs

Central Nervous System Pharmacokinetics of the Mdr1 P-Glycoprotein Substrate CP-615,003: Intersite Differences and Implications for Human Receptor Occupancy Projections from Cerebrospinal Fluid Exposures
Drug Metab Dispos 2007 35: 1341-1349. Published online April 30, 2007; 10.1124/dmd.106.013953 [Abstract] [Full Text] [PDF]  

Chandra Prakash, Donghui Cui, Michael J. Potchoiba, and Todd Butler

Metabolism, Distribution and Excretion of a Selective N-Methyl-D-Aspartate Receptor Antagonist, Traxoprodil, in Rats and Dogs
Drug Metab Dispos 2007 35: 1350-1364. Published online May 11, 2007; 10.1124/dmd.107.016105 [Abstract] [Full Text] [PDF]  

Mohamad Shebley and Paul F. Hollenberg

Mutation of a Single Residue (K262R) in P450 2B6 Leads to Loss of Mechanism-Based Inactivation by Phencyclidine
Drug Metab Dispos 2007 35: 1365-1371. Published online April 25, 2007; 10.1124/dmd.107.014985 [Abstract] [Full Text] [PDF]  

Isabelle J. Létourneau, Andrew J. Slot, Roger G. Deeley, and Susan P. C. Cole

Mutational Analysis of a Highly Conserved Proline Residue in MRP1, MRP2, and MRP3 Reveals a Partially Conserved Function
Drug Metab Dispos 2007 35: 1372-1379. Published online May 9, 2007; 10.1124/dmd.107.015479 [Abstract] [Full Text] [PDF]  

Harvey Wong, Vincent Tong, K. Wayne Riggs, Dan W. Rurak, Frank S. Abbott, and Sanjeev Kumar

Kinetics of Valproic Acid Glucuronidation: Evidence for in Vivo Autoactivation
Drug Metab Dispos 2007 35: 1380-1386. Published online May 11, 2007; 10.1124/dmd.107.015719 [Abstract] [Full Text] [PDF]  

Harvey Wong, Randy C. Dockens, Lori Pajor, Suresh Yeola, James E. Grace, Jr., Arlene D. Stark, Rebecca A. Taub, Frank D. Yocca, Robert C. Zaczek, and Yu-Wen Li

6-Hydroxybuspirone Is a Major Active Metabolite of Buspirone: Assessment of Pharmacokinetics and 5-Hydroxytryptamine_1A Receptor Occupancy in Rats
Drug Metab Dispos 2007 35: 1387-1392. Published online May 9, 2007; 10.1124/dmd.107.015768 [Abstract] [Full Text] [PDF]  

Qi Wang and Marilyn E. Morris

The Role of Monocarboxylate Transporter 2 and 4 in the Transport of -Hydroxybutyric Acid in Mammalian Cells
Drug Metab Dispos 2007 35: 1393-1399. Published online May 14, 2007; 10.1124/dmd.107.014852 [Abstract] [Full Text] [PDF]  

Alexander Treiber, Ralph Schneiter, Stephanie Häusler, and Bruno Stieger

Bosentan Is a Substrate of Human OATP1B1 and OATP1B3: Inhibition of Hepatic Uptake as the Common Mechanism of Its Interactions with Cyclosporin A, Rifampicin, and Sildenafil
Drug Metab Dispos 2007 35: 1400-1407. Published online May 11, 2007; 10.1124/dmd.106.013615 [Abstract] [Full Text] [PDF]  

Micaela C. Damsten, Jan N. M. Commandeur, Alex Fidder, Albert G. Hulst, Daan Touw, Daan Noort, and Nico P. E. Vermeulen

Liquid Chromatography/Tandem Mass Spectrometry Detection of Covalent Binding of Acetaminophen to Human Serum Albumin
Drug Metab Dispos 2007 35: 1408-1417. Published online May 17, 2007; 10.1124/dmd.106.014233 [Abstract] [Full Text] [PDF]  

Felix Waldmeier, Ulrike Glaenzel, Bernard Wirz, Lukas Oberer, Dietmar Schmid, Michael Seiberling, Jessica Valencia, Gilles-Jacques Riviere, Peter End, and Sujata Vaidyanathan

Absorption, Distribution, Metabolism, and Elimination of the Direct Renin Inhibitor Aliskiren in Healthy Volunteers
Drug Metab Dispos 2007 35: 1418-1428. Published online May 17, 2007; 10.1124/dmd.106.013797 [Abstract] [Full Text] [PDF]  

Naomi Mizuno, Tsuyoshi Takahashi, Yumiko Iwase, Hiroyuki Kusuhara, Takuro Niwa, and Yuichi Sugiyama

Human Organic Anion Transporters 1 (hOAT1/SLC22A6) and 3 (hOAT3/SLC22A8) Transport Edaravone (MCI-186; 3-methyl-1-phenyl-2-pyrazolin-5-one) and Its Sulfate Conjugate
Drug Metab Dispos 2007 35: 1429-1434. Published online May 14, 2007; 10.1124/dmd.106.013912 [Abstract] [Full Text] [PDF]  

Alison Betts, Fidelma Atkinson, Iain Gardner, David Fox, Rob Webster, Kevin Beaumont, and Paul Morgan

Impact of Physicochemical and Structural Properties on the Pharmacokinetics of a Series of 1_L-Adrenoceptor Antagonists
Drug Metab Dispos 2007 35: 1435-1445. Published online May 14, 2007; 10.1124/dmd.107.015180 [Abstract] [Full Text] [PDF]  

Short Communications:

Kathrin Klein, Stephan Tatzel, Sebastian Raimundo, Tanja Saussele, Elisabeth Hustert, Jürgen Pleiss, Michel Eichelbaum, and Ulrich M. Zanger

A Natural Variant of the Heme-Binding Signature (R441C) Resulting in Complete Loss of Function of CYP2D6
Drug Metab Dispos 2007 35: 1247-1250. Published online April 25, 2007; 10.1124/dmd.107.015149 [Abstract] [Full Text] [PDF] [Data Supplement]   

Anahita Bhathena, Toby Mueller, David R. Grimm, Ken Idler, Alan Tsurutani, Brian B. Spear, and David A. Katz

Frequency of the Frame-Shifting CYP2D7 138delT Polymorphism in a Large, Ethnically Diverse Sample Population
Drug Metab Dispos 2007 35: 1251-1253. Published online May 9, 2007; 10.1124/dmd.107.014993 [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.