DMD -- Table of Contents (37 [11])

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):
Year:		Vol:		Page:

Receive this page by email each issue: [Sign up for eTOCs]

Other Issues:
November 2009; 37 (11)   [Index by Author] [Cover Caption]

       Articles

       Short Communications

Find articles in this issue containing these words:
[Search ALL Issues]

Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF) |

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Articles:

Akihito Ogasawara, Isao Negishi, Kazumasa Kozakai, and Toshiyuki Kume: In Vivo Evaluation of Drug-Drug Interaction via Mechanism-Based Inhibition by Macrolide Antibiotics in Cynomolgus Monkeys
Drug Metab Dispos 2009 37: 2127-2136. Published online August 24, 2009; 10.1124/dmd.109.028969 [Abstract] [Full Text] [PDF]

Ken-ichi Umehara, Naoyuki Nakada, Kiyoshi Noguchi, Takafumi Iwatsubo, Takashi Usui, and Hidetaka Kamimura: Investigation of Long-Term Retention of Unchanged (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide, A Novel "Funny" If Current Channel Inhibitor, and Its Metabolites in the Eyeball and Thoracic Aorta of Rats
Drug Metab Dispos 2009 37: 2137-2144. Published online August 24, 2009; 10.1124/dmd.109.027813 [Abstract] [Full Text] [PDF]

Katsunobu Hagihara, Miho Kazui, Atsushi Kurihara, Michiharu Yoshiike, Kokichi Honda, Osamu Okazaki, Nagy A. Farid, and Toshihiko Ikeda: A Possible Mechanism for the Differences in Efficiency and Variability of Active Metabolite Formation from Thienopyridine Antiplatelet Agents, Prasugrel and Clopidogrel
Drug Metab Dispos 2009 37: 2145-2152. Published online August 24, 2009; 10.1124/dmd.109.028498 [Abstract] [Full Text] [PDF]

Óscar J. Pozo, Peter Van Eenoo, Koen Deventer, Leen Lootens, Wim Van Thuyne, Maria K. Parr, Wilhelm Schänzer, Juan V. Sancho, Felix Hernández, Philip Meuleman, Geert Leroux-Roels, and Frans T. Delbeke: Detection and Characterization of a New Metabolite of 17 ${alpha}$ -Methyltestosterone
Drug Metab Dispos 2009 37: 2153-2162. Published online August 24, 2009; 10.1124/dmd.109.028373 [Abstract] [Full Text] [PDF]

Michael H. Baumann, Dorota Zolkowska, Insook Kim, Karl B. Scheidweiler, Richard B. Rothman, and Marilyn A. Huestis: Effects of Dose and Route of Administration on Pharmacokinetics of (±)-3,4-Methylenedioxymethamphetamine in the Rat
Drug Metab Dispos 2009 37: 2163-2170. Published online August 13, 2009; 10.1124/dmd.109.028506 [Abstract] [Full Text] [PDF]

G. A. Knudsen, Y. Cheng, R. K. Kuester, M. J. Hooth, and I. G. Sipes: Effects of Dose and Route on the Disposition and Kinetics of 1-Butyl-1-methylpyrrolidinium Chloride in Male F-344 Rats
Drug Metab Dispos 2009 37: 2171-2177. Published online August 24, 2009; 10.1124/dmd.109.029082 [Abstract] [Full Text] [PDF]

Xingguo Cheng and Curtis D. Klaassen: Tissue Distribution, Ontogeny, and Hormonal Regulation of Xenobiotic Transporters in Mouse Kidneys
Drug Metab Dispos 2009 37: 2178-2185. Published online August 13, 2009; 10.1124/dmd.109.027177 [Abstract] [Full Text] [PDF]

Helena Anna Thörn, Mikael Hedeland, Ulf Bondesson, Lars Knutson, Mohammed Yasin, Paul Dickinson, and Hans Lennernäs: Different Effects of Ketoconazole on the Stereoselective First-Pass Metabolism of R/S-Verapamil in the Intestine and the Liver: Important for the Mechanistic Understanding of First-Pass Drug-Drug Interactions
Drug Metab Dispos 2009 37: 2186-2196. Published online August 17, 2009; 10.1124/dmd.109.028027 [Abstract] [Full Text] [PDF]

Kazuaki Taguchi, Yukino Urata, Makoto Anraku, Hiroshi Watanabe, Daisuke Kadowaki, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Eishun Tsuchida, Toru Maruyama, and Masaki Otagiri: Hemoglobin Vesicles, Polyethylene Glycol (PEG)ylated Liposomes Developed as a Red Blood Cell Substitute, Do Not Induce the Accelerated Blood Clearance Phenomenon in Mice
Drug Metab Dispos 2009 37: 2197-2203. Published online August 13, 2009; 10.1124/dmd.109.028852 [Abstract] [Full Text] [PDF]

Laura K. Chico, Heather A. Behanna, Wenhui Hu, Guifa Zhong, Saktimayee Mitra Roy, and D. Martin Watterson: Molecular Properties and CYP2D6 Substrates: Central Nervous System Therapeutics Case Study and Pattern Analysis of a Substrate Database
Drug Metab Dispos 2009 37: 2204-2211. Published online August 6, 2009; 10.1124/dmd.109.028134 [Abstract] [Full Text] [PDF] [Data Supplement]

Andrea E. Schwaninger, Markus R. Meyer, Josef Zapp, and Hans H. Maurer: The Role of Human UDP-Glucuronyltransferases on the Formation of the Methylenedioxymethamphetamine (Ecstasy) Phase II Metabolites R- and S-3-Methoxymethamphetamine 4-O-Glucuronides
Drug Metab Dispos 2009 37: 2212-2220. Published online August 10, 2009; 10.1124/dmd.109.029215 [Abstract] [Full Text] [PDF]

Taina Sten, Mika Kurkela, Tiia Kuuranne, Antti Leinonen, and Moshe Finel: UDP-Glucuronosyltransferases in Conjugation of 5 ${alpha}$ - and 5β-Androstane Steroids
Drug Metab Dispos 2009 37: 2221-2227. Published online August 6, 2009; 10.1124/dmd.109.029231 [Abstract] [Full Text] [PDF]

Marc Le Vee, Valérie Lecureur, Amélie Moreau, Bruno Stieger, and Olivier Fardel: Differential Regulation of Drug Transporter Expression by Hepatocyte Growth Factor in Primary Human Hepatocytes
Drug Metab Dispos 2009 37: 2228-2235. Published online August 6, 2009; 10.1124/dmd.109.028035 [Abstract] [Full Text] [PDF]

Jelena Tojcic, Marie-Odile Benoit-Biancamano, Michael H. Court, Robert J. Straka, Patrick Caron, and Chantal Guillemette: In Vitro Glucuronidation of Fenofibric Acid by Human UDP-Glucuronosyltransferases and Liver Microsomes
Drug Metab Dispos 2009 37: 2236-2243. Published online August 6, 2009; 10.1124/dmd.109.029058 [Abstract] [Full Text] [PDF]

Michiko Sugawara, Kiyoshi Okamoto, Tadashi Kadowaki, Kazutomi Kusano, Akiyoshi Fukamizu, and Tsutomu Yoshimura: Inoculation of Human Tumor Cells Alters the Basal Expression but Not the Inducibility of Cytochrome P450 Enzymes in Tumor-Bearing Mouse Liver
Drug Metab Dispos 2009 37: 2244-2254. Published online August 10, 2009; 10.1124/dmd.109.028571 [Abstract] [Full Text] [PDF] [Data Supplement]

Zoe Riches, Emma L. Stanley, Jackie C. Bloomer, and Michael W. H. Coughtrie: Quantitative Evaluation of the Expression and Activity of Five Major Sulfotransferases (SULTs) in Human Tissues: The SULT "Pie"
Drug Metab Dispos 2009 37: 2255-2261. Published online August 13, 2009; 10.1124/dmd.109.028399 [Abstract] [Full Text] [PDF]

Su-Jun Lee, Woo-Young Kim, Hyunmi Kim, Ji-Hong Shon, Sang Seop Lee, and Jae-Gook Shin: Identification of New CYP2C19 Variants Exhibiting Decreased Enzyme Activity in the Metabolism of S-Mephenytoin and Omeprazole
Drug Metab Dispos 2009 37: 2262-2269. Published online August 6, 2009; 10.1124/dmd.109.028175 [Abstract] [Full Text] [PDF]

Short Communications:

Mariko Nakano, Edward J. Kelly, and Allan E. Rettie: Expression and Characterization of CYP4V2 as a Fatty Acid ${omega}$ -Hydroxylase
Drug Metab Dispos 2009 37: 2119-2122. Published online August 6, 2009; 10.1124/dmd.109.028530 [Abstract] [Full Text] [PDF]

Kristin J. Metry, Jason R. Neale, Jean Bendaly, Ned B. Smith, William M. Pierce, Jr., and David W. Hein: Effect of N-Acetyltransferase 2 Polymorphism on Tumor Target Tissue DNA Adduct Levels in Rapid and Slow Acetylator Congenic Rats Administered 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-Amino-3,8-dimethylimidazo-[4,5-f]quinoxaline
Drug Metab Dispos 2009 37: 2123-2126. Published online August 10, 2009; 10.1124/dmd.109.029512 [Abstract] [Full Text] [PDF]

Cover Caption:

About the cover: The human sulfotransferase pies: The mean expression values for each enzyme are displayed as percentages of the total sum of immunoquantified SULTs (maximum 5 enzymes) present in each tissue. See article by Riches et al. on page 2255 of this issue.