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Future Table of Contents: October 2008; 36 (10)

CENTENNIAL PERSPECTIVE

SHORT COMMUNICATION

ARTICLES

CENTENNIAL PERSPECTIVE

Patrick Murphy

The Development of Drug Metabolism Research as Expressed in the Publications of ASPET Part 3, 1984-2008 (Fast Forward 17 July 2008)

SHORT COMMUNICATION

Abhinav Nath, and William M. Atkins

Principal Component Analysis of CYP2C9 and CYP3A4 Probe Substrate/Inhibitor Panels (Fast Forward 19 June 2008)

ARTICLES

Anand K Deo, and Stelvio M Bandiera

Identification of Human Hepatic Cytochrome P450 Enzymes Involved in the Biotransformation of Cholic and Chenodeoxycholic Acid (Fast Forward 26 June 2008)

Guoying Tai, Leslie Dickmann, Nicholas Matovic, James DeVoss, Elizabeth Gillam, and Allan Rettie

Re-Engineering of CYP2C9 to Probe Acid-Base Substrate Selectivity (Fast Forward 7 July 2008)

Vadim Mozhaev, Lyudmila Mozhaeva, Peter Michels, and Yuri Khmelnitsky

Extractive Biotransformation for Production of Metabolites of Poorly Soluble Compounds. Synthesis of 32-Hydroxy-Rifalazil (Fast Forward 7 July 2008)

Takashi Okura, Asami Hattori, Yusuke Takano, Takenori Sato, Margareta Hammarlund-Udenaes, Tetsuya Terasaki, and Yoshiharu Deguchi

Involvement of the Pyrilamine Transporter, a Putative Organic Cation Transporter, in Blood-Brain Barrier Transport of Oxycodone (Fast Forward 7 July 2008)

Hua Gao, Lili Yao, Heather W Mathieu, Ying Zhang, Tristan S Maurer, Matthew D Troutman, Dennis O Scott, Roger B Ruggeri, and Jing Lin

In Silico Modeling of Non-specific Binding to Human Liver Microsomes (Fast Forward 7 July 2008)

Satoshi Kitamura, Kazuya Maeda, Yi Wang, and Yuichi Sugiyama

Involvement of multiple transporters in the hepatobiliary transport of rosuvastatin (Fast Forward 10 July 2008)

Zaineb Fadhel Albayati, Linda P Dwoskin, and Peter Anthony Crooks

Pharmacokinetics of the novel nicotinic receptor antagonist, N,N’-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB) (Fast Forward 10 July 2008)

Nancy M. Jackson, and Thomas A. Kocarek

Suppression of CYP2B Induction by Alendronate-Mediated Farnesyl Diphosphate Synthase Inhibition in Primary Cultured Rat Hepatocytes (Fast Forward 10 July 2008)

Kazuhiko Hanada, Yasutaka Ikemi, Kazutaka Kukita, Kiyoshi Mihara, and Hiroyasu Ogata

Stereoselective First-Pass Metabolism of Verapamil in the Small Intestine and Liver in Rats (Fast Forward 10 July 2008)

Melanie Grondin, Francine Hamel, Fathey Sarhan, and Diana Averill-Bates

Metabolic Activity of Cytochrome P450 Isoforms in Hepatocytes Cryopreserved with Wheat Protein Extract (Fast Forward 10 July 2008)

H Markus Weiss, Ulrike Pfaar, Alain Schweitzer, Hansjorg Wiegand, Andrej Skerjanec, and Horst Schran

Biodistribution and Plasma Protein Binding of Zoledronic Acid (Fast Forward 14 July 2008)

Nina Kassner, Klaus Huse, Hans-Jorg Martin, Ute Godtel-Armbrust, Annegret Metzger, Ingolf Meineke, Jurgen Brockmoller, Kathrin Klein, Ulrich M Zanger, Edmund Maser, and Leszek Wojnowski

CBR1 Is a Predominant Doxorubicin Reductase in the Human Liver (Fast Forward 17 July 2008)

Wenchang Guo, Philip Reigan, David Siegel, and David Ross

Enzymatic Reduction and Glutathione Conjugation of Benzoquinone Ansamycin Hsp90 Inhibitors: Relevance for Toxicity and Mechanism of Action (Fast Forward 17 July 2008)

Yury Kapelyukh, Mark J. Paine, Jean-Didier Marechal, Michael J Sutcliffe, C. Roland Wolf, and Gordon Roberts

Multiple Substrate Binding by Cytochrome P450 3A4: Estimation of the Number of Bound Substrate Molecules (Fast Forward 21 July 2008)

Tsutomu Matsubara, Kouichi Yoshinari, Kazunobu Aoyama, Mika Sugawara, Yuji Sekiya, Kiyoshi Nagata, and Yasushi Yamazoe

Role of Vitamin D Receptor in the Lithocholic Acid-Mediated CYP3A Induction in Vitro and In Vivo (Fast Forward 21 July 2008)

Chandra Prakash, Chen Weichao, Michelle Rossulek, Kim Johnson, Chenghong Zhang, Thomas O'Connell, Michael Potchoiba, and Deepak Dalvie

Metabolism, Pharmacokinetics, and Excretion of a Cholesteryl Ester Transfer Protein Inhibitor, Torcetrapib, in Rats, Monkeys, and Mice: Characterization of Unusual and Novel Metabolites by High Resolution LC-MS/MS and 1H NMR (Fast Forward 24 July 2008)

Tomohiro Nishimura, Yoshiaki Seki, Kazuko Sato, Takuya Chishu, Noriko Kose, Tetsuya Terasaki, Young-sook Kang, Yoshimichi Sai, and Emi Nakashima

Enhancement of Zidovudine Uptake by Dehydroepiandrosterone Sulfate in Rat Syncytiotrophoblast Cell Line TR-TBT 18d-1 (Fast Forward 24 July 2008)

Kristina K. Wolf, Kenneth R. Brouwer, Gary M. Pollack, and Kim LR Brouwer

Effect of Albumin on the Biliary Clearance of Compounds in Sandwich-Cultured Rat Hepatocytes (Fast Forward 24 July 2008)

Chandra Prakash, Weiwei wang, Thomas O'Connell, and Kim Johnson

CYP2C8 and CYP3A Mediated C-Demethylation of (3-{[4-Tert-Butyl-Benzyl)-(Pyridine-3- Sulfonyl)-Amino]-Methyl}-Phenoxy)Acetic Acid (CP-533,536), an EP2 Receptor-Selective Prostaglandin E2 Agonist: Characterization of Metabolites by High Resolution LC-MS/MS and LC/MS-NMR (Fast Forward 24 July 2008)

Jian Guo, Ang Liu, Hongmei Cao, Yan Luo, John M. Pezzuto, and Richard B. van Breemen

Biotransformation of the Chemopreventive Agent Isoliquiritigenin by UDP-Glucuronosyltransferases (Fast Forward 24 July 2008)